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Boehringer Biochemia Robin S.p.A. Patents |
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Assignee: Boehringer Biochemia Robin S.p.A.
Address: Milan, IT
No. of patents: 21
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| 5162320 |
1,4-bis(alkylamino)-2,3-diaza-anthracene-9,10-diones |
November 10, 1992 |
| Compounds of formula I are described, ##STR1## wherein: R.sub.1 and R.sub.2, that can be the same or different, are hydrogen or acyl groups;R.sub.3 and R.sub.4, that can be the same or different, are hydrogen or optionally substituted alkyl groups.The compounds of formula I are prepa |
| 5145848 |
Amino anthracenediones-bis platinum complexes, useful as antitumoral agents |
September 8, 1992 |
| Compounds of the formula: ##STR1## are disclosed, such as 1,4-bis[2(3,6,9-trioxa)undecylamino-ethylamino]-5,8-dihydroxy anthraquinone 2HCl.These compounds exhibit antineoplastic activity and can be used to treat tumors. |
| 5145789 |
Device and method for pregnancy detection |
September 8, 1992 |
| A device to determine human chorionic gonadotropin (hCG) in urine is described. It includes:a) a first area, consisting of a material able to draw urine by capillarity, on which an hCG bioselective colored agent is absorbed, an end of said first area, to be dipped in urine, while the oth |
| 5081013 |
Immunodiagnostic device and method |
January 14, 1992 |
| A method of, and a device for performing immune enzyme analyses are described, wherein positiveness or negativeness of an analysis is evaluated by colorimetric comparison of a chromogen zone of determination with a chromogen zone of reference, on which zones reactions are occurring, |
| 5075324 |
Aralkyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical composition cont |
December 24, 1991 |
| 1,4-dihydropyridines of formula I ##STR1## wherein X is --CO.sub.2 R.sub.1, cyano, nitro, --COCH.sub.3 ; each of R and R.sub.1, which are the same or different, is a primary, secondary or tertiary, saturated or unsaturated, linear or branched C.sub.1 -C.sub.6 alkyl group optional |
| 5047414 |
2-(aminoalkylthio)methyl-1,4-dihydropyridine, a method for the preparation thereof and pharmaceu |
September 10, 1991 |
| Compounds of formula I, and pharmaceutical compositions containing compounds of formula I ##STR1## wherein: R.sub.1 is:(a) COCH.sub.3, COC.sub.6 H.sub.5, CN or NO.sub.2 ;(b) COORa wherein Ra is hydrogen, or optionally substituted C.sub.1 -C.sub.6 straight or branched alkyl;R.sub.2 is |
| 4999362 |
2-thiomethyl-substituted-1,4-dihydropyridines, method for their preparation and pharmaceutical c |
March 12, 1991 |
| Compounds of formula I ##STR1## wherein R.sub.1 is an alkoxycarbonyl group, acetyl, benzoyl, cyano, nitro or aminocarbonyl;R.sub.2 is an optionally substituted aryl or hetaryl group;R.sub.3 is an alkoxycarbonyl group;.phi. is a thio residue such as alkylthio, cycloalkylthio, arylthio, |
| 4988713 |
2-selenomethyl-1,4-dihydropyridines having calcium-antagonistic properties and pharmaceutical co |
January 29, 1991 |
| Compounds of formula I ##STR1## wherein R.sub.1 is a cyano, nitro, acetyl, benzoyl or alkoxycarbonyl group;R.sub.2 is an optionally substituted phenyl or heteroaryl group;R.sub.3 is an alkoxycarbonyl group;R.sub.4 is an alkyl group, optionally substituted by hydroxy, amino, phenyl, h |
| 4988701 |
Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical composi |
January 29, 1991 |
| Cyclic amino-thioacetal amides of formula I ##STR1## wherein X is O, S, p is 1 or 2, R and R.sub.1 are optionally esterified hydrogen or carboxy, A is a single bond, methylene or ethylene, m is zero or 1, n is an integer 1 to 7 and y is a imidazole or .beta.-pyridylmethyl residue |
| 4956369 |
2-dithioalkyl-dihydropyridines and pharmaceutical compositions containing them |
September 11, 1990 |
| Compounds of formula I ##STR1## wherein R.sub.1 and R.sub.3, which are the same or different, are alkoxycarbonyl, acetyl, cyano, nitro, benzoyl or amino-carbonyl groups,R.sub.2 is differently substituted aryl or heteroaryl group;R.sub.4 is a C.sub.1 -C.sub.12 alkyl group optionally subst |
| 4918087 |
2-thiomethyl-substituted-pyridine and -3,5-dicarboxylates having anti-hypertensive activity |
April 17, 1990 |
| Pyridines of formula I ##STR1## wherein R.sub.1 is acetyl, benzoyl, cyano, nitro, alkoxycarbonyl or aminocarbonyl groups; R.sub.2 is an optionally substituted aryl or a heterocyclic group; and .phi. is a sulphurated residue such as alkylthio, cycloakylthio, arylthio, heteroarylth |
| 4871528 |
Pharmaceutical compositions having antineoplastic activity |
October 3, 1989 |
| Pharmaceutical compositions containing unit or separate dosages of 2.5 to 5 grams of reduced glutathione (GSH) and known anti-tumor agents, to be used simultaneously, separately or sequentially in anti-tumor therapy.Compounds of the invention, that can be used both in mono- or polychemot |
| 4857643 |
Antitussive and mucus regulating 2-substituted thiazolidines |
August 15, 1989 |
| 2-Substituted thiazolidines compounds having formula I ##STR1## wherein X is a CH.sub.2, O or S, R is hydroxy or an acyloxy, alkyloxy, alkenyloxy or alkinyloxy group, R.sub.1 is hydrogen or a group of formula ##STR2## R.sub.2 is hydrogen or a free or esterified carboxy group, R.s |
| 4849437 |
2-sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions |
July 18, 1989 |
| Thiazolidines of formula I ##STR1## wherein R is H, C.sub.1 -C.sub.4 -alkyl, allyl or propargyl;X is O, CH.sub.2, S;R.sub.1 is C.sub.1 -C.sub.6 -linear or branched alkyl, phenyl, benzyl, or a group of formula CH.sub.2 --CH.sub.2 --O--(CH.sub.2 --CH.sub.2 --O).sub.n --Ra wherein n is |
| 4845113 |
2-substituted -1,4-dihydropyridines and pharmaceutical compositions containing them |
July 4, 1989 |
| Compounds of formula I ##STR1## wherein R is hydrogen or lower alkyl; R.sub.1 is acetyl, benzoyl, cyano, nitro, carboxy, alkoxycarbonyl or aminocarbonyl groups; R.sub.2 is an optionally substituted aryl or hetaryl residue; R.sub.3 is a carboxy or alkoxycarbonyl group; A is a cycl |
| 4842995 |
Diagnostic method for the evaluation of clinical parameters by direct collection of biological m |
June 27, 1989 |
| This invention relates to a device for the diagnostic evaluation of clinical parameters by direct collection of biological materials consisting of a solid support, of suited materials, shape and size, carrying fixed on its surface a pre-established quantity of an antibody, in the cas |
| 4839348 |
1,4-dihydropyridines |
June 13, 1989 |
| Dihydropyridines of formula I ##STR1## wherein R is hydrogen or lower alkyl; R.sub.1 is a CN, NO.sub.2, COCH.sub.3, COPh group, a carboalkoxy or carboamide group; R.sub.2 is an aromatic or heteroaromatic, mono- or bicyclic eventually substituted phenyl group; R.sub.3 is a carboal |
| 4798898 |
Antitussive and mucus regulating 2-substituted thiazolidines |
January 17, 1989 |
| 2-Substituted thiazolidines compounds having formula I ##STR1## wherein X is a CH.sub.2, O or S, R is hydroxy or an acyloxy, alkyloxy, alkenyloxy or alkinyloxy group, R.sub.1 is hydrogen or a group of formula ##STR2## R.sub.2 is hydrogen or a free or esterified carboxy group, R.s |
| 4749798 |
Fluoro coumarins as antilymphoedema agents |
June 7, 1988 |
| A compound of the formula ##STR1## wherein hydrogen, fluorine, chlorine or bromine; B is fluorine, or when A is fluorine B may be hydrogen;R is hydrogen, C.sub.1 -C.sub.8 branched or unbranched alkyl, CH.sub.2 BR, CH.sub.2 Cl or substituted or unsubstituted phenyl;X is hydrogen, chlo |
| 4732893 |
Amino-anthracenediones-platinum complexes useful as anticancer compounds |
March 22, 1988 |
| Platinum complex having formula (I)whereinm is 1 or 2;X and X', which are the same or different, are Cl, OH, CH.sub.3 SOCH.sub.3.Cl or CH.sub.3 SOCH.sub.3.H.sub.2 O;L is a bidentate ligand of formula II ##STR1## Solv. represents the crystallization solvents and m is zero, 0.5 or an i |
| 4692447 |
Tricyclic dihydropyridazinones and pharmaceutical compositions containing them |
September 8, 1987 |
| The tricyclic dihydropyridazinone derivatives having formula I ##STR1## are endowed with interesting hypotensive, vasodilating, antiaggregant, antithrombotic and cytoprotective properties and are therefore useful in human or veterinary medicine. |
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