| Patent Number |
Title Of Patent |
Date Issued |
| D417264 |
Gutter guard |
November 30, 1999 |
|
| 7362815 |
Time-reversal block transmit diversity system for channels with intersymbol interference and met |
April 22, 2008 |
| A method for diversity transmission and reception for channels with intersymbol interference is created. With this method one can transmit from two or more antennas in such a way that a receiver with one or more antennas can benefit from the diversity offered by the difference in cha |
| 7336525 |
Nonvolatile memory for logic circuits |
February 26, 2008 |
| A memory circuit that retains stored data upon power down includes a volatile data storage circuit; and at least one nonvolatile memory coupled within the volatile data storage circuit, wherein the at least one nonvolatile memory includes a high resistive state and a low resistive st |
| 7332271 |
Apparatus and methods for parallel processing of micro-volume liquid reactions |
February 19, 2008 |
| Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers |
| 7288892 |
Plasma display panel with improved cell geometry |
October 30, 2007 |
| A cell geometry for a coplanar electrode plasma display panel consisting of two transparent plates, one with parallel sustain electrodes, and the other with address electrodes deposited on their surface. The electrodes are covered with a dielectric film. A protective MgO layer is deposit |
| 7272192 |
Time-reversal block transmit diversity system for channels with intersymbol interference and met |
September 18, 2007 |
| A method for diversity transmission and reception for channels with intersymbol interference is created. With this method one can transmit from two or more antennas in such a way that a receiver with one or more antennas can benefit from the diversity offered by the difference in cha |
| 7232842 |
Kinase inhibitors and associated pharmaceutical compositions and methods of use |
June 19, 2007 |
| The invention provides novel compounds useful as kinase inhibitors or as starting materials And/or intermediates in the synthesis of compounds useful as kinase inhibitors. The compounds have The general structure of formula (I) ##STR00001## wherein A is a 3- to 8-membered ring, opti |
| 7216123 |
Methods for ranking nodes in large directed graphs |
May 8, 2007 |
| Techniques for assigning ranks to nodes in a large linked database, such as world wide web or any other hypermedia database, partition the nodes so that the link matrix has a predominantly block-diagonal form. Within each block, a local rank is computed for nodes in the block, possibly b |
| 7185697 |
Electroosmotic microchannel cooling system |
March 6, 2007 |
| Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated |
| 7151116 |
Apoptolidin analogs and derivatives for inducing apoptosis in transformed cells |
December 19, 2006 |
| The invention provides novel apoptosis-inducing compounds that include isolated, purified isoapoptolidin, and selectively functionalized isoapoptolidin derivatives and stereoisomers thereof; selectively functionalized apoptolidin derivatives and stereoisomers thereof; and deglycosyla |
| 7130042 |
Dual axis fluorescence microscope with modulated input |
October 31, 2006 |
| A dual beam confocal microscope is provided. An optical source assembly provides two mutually coherent optical beams differing in frequency by a frequency difference .DELTA.f. The two beams are received by focusing assemblies that provide two focused beams to a sample. The focused beams |
| 7089787 |
Torsional harmonic cantilevers for detection of high frequency force components in atomic force |
August 15, 2006 |
| A cantilever for the use in atomic force microscopy includes a cantilever arm having a fixed end being attached to a base member and a free end where the cantilever arm has a first shape and an axis of torsion associated with the first shape, and a probe tip projecting from the canti |
| 7070780 |
Treatment of demyelinating autoimmune disease with ordered peptides |
July 4, 2006 |
| Compositions and methods are provided for the treatment of demyelinating autoimmune disease. Therapeutic doses are administered of an ordered peptide comprising a repeated motif {SEQ ID NO: 1} [.sup.1E.sup.2Y.sup.3Y.sup.4K].sub.n, where n is from 2 to 6. Some specific peptides of int |
| 7042920 |
Phased array gratings and tunable lasers using same |
May 9, 2006 |
| A tunable laser comprises multiple reflectors defining a resonant cavity, and an optical gain medium positioned within the resonant cavity. One of the reflectors is a programmable micromirror array that acts as a tunable blazed diffraction grating providing continuous tuning of a single |
| 6982082 |
Gene therapy by cell specific targeting |
January 3, 2006 |
| This invention is directed to a modified cyclosporin A and to a modified, genetically engineered version of its receptor, cyclophilin. This invention is further directed to a method for treating host versus graft disease following blood marrow transplantation by transfecting stem cells |
| 6939691 |
E. coli and Streptomyces host cells that contain MatBC genes or E. coli host cells that contain |
September 6, 2005 |
| The use of enzymes that catalyze the production of starter and extender units for polyketides in E. coli and Streptomyces is described; these enzymes include malonyl CoA decarboxylase (MatA), malonyl CoA synthetase (MatB), and a malonate transporter (MatC) as well as proprionyl CoA c |
| 6939533 |
Non-invasive localization of a light-emitting conjugate in a mammal |
September 6, 2005 |
| Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disc |
| 6916462 |
Non-invasive localization of a light-emitting conjugate in a mammal |
July 12, 2005 |
| Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disc |
| 6913882 |
Methods of screening for B cell activity modulators |
July 5, 2005 |
| The invention provides for the identification of all genes, whether known or novel, which are differentially expressed within and among B cells, making possible the characterization of their temporal regulation and function in the B cell response and/or in B cell mediated disorders. |
| 6908605 |
Non-invasive localization of a light-emitting conjugate in a mammal |
June 21, 2005 |
| Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disc |
| 6891021 |
Regulated apoptosis |
May 10, 2005 |
| We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered |
| 6890515 |
Non-invasive localization of a light-emitting conjugate in a mammal |
May 10, 2005 |
| Methods an compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease state are disclosed, |
| 6801939 |
Method for evaluating quality of service of a digital network connection |
October 5, 2004 |
| A technique for measuring, evaluating, and presenting virtual network connection latency and virtual network connection stability information allows users to easily evaluate the quality of internet connections in real time. The technique uses audible sounds to represent the round trip |
| 6789426 |
Microfluidic channels with integrated ultrasonic transducers for temperature measurement and met |
September 14, 2004 |
| There is described a method and apparatus for measuring temperature of a fluid in a microchannel of the type having spaced walls. An ultrasonic transducer transmits ultrasonic waves transmitted from one wall to the opposite wall. A processor determines the time-of-flight of the ultrasoni |
| 6753173 |
Methods to mediate polyketide synthase module effectiveness |
June 22, 2004 |
| Linking sequences that modulate cross-talk between modules of Type I polyketide synthases have been identified and methods for their use are described. Arbitrarily chosen modules can be mixed and matched by supplying the appropriate linkers to facilitate transfer of a growing polyket |
| 6750040 |
Cell-free synthesis of polyketides |
June 15, 2004 |
| Cell-free systems which effect the production of polyketides employing modular polyketide synthases are described. Libraries of new and/or known polyketides may also be produced in cell-free systems employing aromatic PKS, modular PKS or both. |
| 6726895 |
Method of imaging cell death in vivo |
April 27, 2004 |
| A method of imaging apoptosis in vivo, using radiolabeled annexin, is described. Methods for tumor radiotherapy are also provided. |
| 6605115 |
Method and composition for inhibiting cardiovascular cell proliferation |
August 12, 2003 |
| Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a polymer consisting of from 6 to about 30 amino acid subunits, where at least 50% of the subunit |
| 6455247 |
Methods for screening for transdominant effector peptides and RNA molecules |
September 24, 2002 |
| Methods and compositons for screening for transdominant effector peptides and RNA molecules selected inside living cells from randomized pools are provided. |
| 6452387 |
Catalyzing the transient response in steady-state MRI sequences |
September 17, 2002 |
| A steady-state condition for tipped nuclear spins is accelerated or catalyzed by first determining magnetization magnitude of the steady state and the scaling magnetization along one axis (Mz) to at least approximate the determined magnetization magnitude. Then the scaled magnetization i |
| 6442566 |
Frame-based knowledge representation system and methods |
August 27, 2002 |
| A frame-based knowledge representation system is built on a relational database that is completely transparent to the user. A user at a client machine sends standard knowledge base queries across a distributed computer system and the system translates the queries into a language suit |
| 6388052 |
NF-AT polypeptides and polynucleotides |
May 14, 2002 |
| The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplification probes for detecting polynu |
| 6365891 |
Optical sensor array having multiple rungs between distribution and return buses and having ampl |
April 2, 2002 |
| The present invention significantly improves the signal to noise ratio (SNR) in a passive optical array comprising sensors located in rungs between a distribution bus and a return bus. Erbium-doped optical fiber amplifiers are included in the buses proximate to each rung coupling to |
| 6312899 |
NF-AT polypeptides and polynucleotides |
November 6, 2001 |
| The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplification probes for detecting polynu |
| 6307368 |
Linear combination steady-state free precession MRI |
October 23, 2001 |
| A fast, spectrally-selective steady-state free precession (SSFP) imaging method is presented. Combining k-space data from SSFP sequences with certain phase schedules of radiofrequency excitation pulses permits manipulation of the spectral selectivity of the image. For example, lipid |
| 6300626 |
Time-of-flight mass spectrometer and ion analysis |
October 9, 2001 |
| An ion beam supplied from a source is modulated so that ions at a constant flux is passed during on periods or portions thereof and are deflected or stopped during off periods according to a binary sequence in order to encode the ion beam with phase information of the sequence. The binar |
| 6291927 |
Micromachined two dimensional array of piezoelectrically actuated flextensional transducers |
September 18, 2001 |
| A transducer suitable for ultrasonic applications, fluid drop ejection and scanning force microscopy. The transducer comprises a thin piezoelectric ring bonded to a thin fully supported clamped membrane. Voltages applied to said piezoelectric ring excite axisymmetric resonant modes in th |
| 6268728 |
Phase-sensitive method of radio-frequency field mapping for magnetic resonance imaging |
July 31, 2001 |
| Inhomogeneity of the radio-frequency (RF) field B.sub.1 interferes with imaging methods such as fat saturation which are sensitive to variations in the tip angle achieved by an RF pulse. In addition, in the common case in which the MR signal is received through the same coil used for |
| 6250161 |
Ultrasonic photoresist process monitor and method |
June 26, 2001 |
| There is provided a monitor and method for monitoring the condition of a photoresist film on a wafer in which the phase of high frequency ultrasonic pulses reflected from the wafer/photoresist interface provides an indication of the condition of the photoresist film. |
| 6242566 |
Ligand (ACT-4-L) to a receptor on the surface of activated CD4+ T-cells |
June 5, 2001 |
| The invention provides ligands and fragments thereof to a receptor on the surface of activated CD4.sup.+ T-cells. An exemplary ligand is designated ACT-4-L-h-1. Preferred fragments include purified extracellular domains of ligands. The invention also provides humanized and human antibodi |
| 6242163 |
Shape deposition manufacturing of microscopic ceramic and metallic parts using silicon molds |
June 5, 2001 |
| Micro-Mold Shape Deposition Manufacturing (.mu.-Mold SDM) is a method for fabricating complex, three-dimensional microstructures from layered silicon molds. Silicon wafers are etched using conventional silicon-processing techniques to produce wafers with surface patterns, some of whi |
| 6236738 |
Spatiotemporal finite element method for motion analysis with velocity data |
May 22, 2001 |
| Disclosed is a method for nonrigid cyclic motion analysis using a series of images covering the cycle, acquired, for example, from phase contrast magnetic resonance imaging. The method is based on fitting a global spatiotemporal finite element mesh model to motion data samples of an |
| 6219571 |
Magnetic resonance imaging using driven equilibrium fourier transform |
April 17, 2001 |
| A new technique for imaging a material with a high T2/T1 ratio such as articular cartilage uses driven equilibrium Fourier transform (DEFT), a method of enhancing signal strength without waiting for full T1 recovery. Compared to other methods, DEFT imaging provides a good combination of |
| 6215306 |
Magnetic resonance imaging using off-centered spiral trajectories |
April 10, 2001 |
| The quality of spiral images depends on whether actual k-space sampling points are at their nominal positions. Although newer gradient systems can provide more accurate gradient waveforms, timing mis-registration between data acquisition and gradient systems can significantly distort the |
| 6190752 |
Thin films having rock-salt-like structure deposited on amorphous surfaces |
February 20, 2001 |
| A thin film of material having a rock-salt-like structure is deposited on a smooth amorphous substrate surface by ion beam assisted deposition. |
| 6165977 |
Isozyme-specific activators of protein kinase C methods and compositions |
December 26, 2000 |
| Isozyme-specific agonists or activators of .epsilon.PKC are disclosed. The agonists include peptides corresponding to the region of .epsilon.PKC between about amino acids 85 and 92. Also disclosed are therapeutic methods employing such .epsilon.PKC-specific agonists to induce precond |
| 6150099 |
NF-AT polypeptides and polynucleotides |
November 21, 2000 |
| The invention provides novel polypeptides which are associated with the transcription complex NF-AT, polynucleotides encoding such polypeptides, antibodies which are reactive with such polypeptides, polynucleotide hybridization probes and PCR amplification probes for detecting polynu |
| 6144873 |
Method of efficient data encoding in dynamic magnetic resonance imaging |
November 7, 2000 |
| MRI is used to monitor the time behavior or an organ of interest. Images of such organ may change in time due to physiological motion, and/or due to contrast-agent accumulation. Dynamic applications generally involve acquiring data in a k-t space, which contains both temporal and spatial |
| 6135998 |
Method and apparatus for pulsed plasma-mediated electrosurgery in liquid media |
October 24, 2000 |
| A method for performing electrosurgery using sub-microsecond, high-power electrical pulses applied to an electrosurgical probe endface. The probe endface has an area of about 200-1000 microns.sup.2. The pulses have a duration less than 300 nanoseconds, and preferably have very fast r |
| 6107452 |
Thermally and/or photochemically crosslinked electroactive polymers in the manufacture of opto-e |
August 22, 2000 |
| Preparation of thermally and/or photochemically crosslinkable oligomeric precursors and the use of those oligomeric precursors in preparing crosslinked electroactive polymers are described. The oligomers, polymers, and synthetic methods find utility in the manufacture of opto-electronic |
