| Patent Number |
Title Of Patent |
Date Issued |
| 7118853 |
Methods of classifying, diagnosing, stratifying and treating cancer patients and their tumors |
October 10, 2006 |
| The invention provides a variety of reagents for use in the diagnosis and management of breast cancer. The invention utilizes cDNA microarray technology to identify genes whose expression profile across a large group of tumor samples correlates with that of cytokeratin 5 and cytokera |
| 7091324 |
Prevention and treatment of HCV infection employing antibodies directed against conformational e |
August 15, 2006 |
| Conformational epitopes of the envelope protein E2 of the Hepatitis C virus (HCV) have been identified and characterized using a panel of monoclonal antibodies derived from patients infected with HCV. These conformational epitopes have been determined to be important in the immune re |
| 6972193 |
Regulated transcription of targeted genes and other biological events |
December 6, 2005 |
| Dimerization and oligomerization of proteins are general biological control mechanisms that contribute to the activation of cell membrane receptors, transcription factors, vesicle fusion proteins, and other classes of intra- and extracellular proteins. We have developed a general procedu |
| 6316418 |
Regulated apoptosis |
November 13, 2001 |
| We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered |
| 6130337 |
Enantiomerically enriched .alpha.,.alpha.-distributed amino acids and method |
October 10, 2000 |
| Compositions and methods for the preparation of enantiomerically enriched .alpha.,.alpha.-disubstituted amino acid precursors are presented. Briefly, allylic electrophiles are alkylated with oxazolones in the presence of a base and catalytic quantities of a transition metal complex i |
| 5292977 |
Palladium catalyzed alkylative cyclization useful in synthesis of vitamin D and analogues |
March 8, 1994 |
| An alkylative cycloaddition method is provided that is particularly useful for the synthesis of many of the Vitamin D analogues with differing side chains. Thus, a preferred synthesis is of Vitamin D analogues having a side chain R.sub.1 where a substantially geometrically pure first |
| 4292227 |
Stable supersaturated solutions of sparingly soluble salts |
September 29, 1981 |
| Method and compositions are provided concerning stable supersaturated aqueous solutions of sparingly soluble inorganic salts. The method involves exceeding the solubility level of a sparingly soluable inorganic salt in water at ambient temperatures in the presence of polyanionic poly |
| 4052129 |
Method of and apparatus for measuring the wavelength of a source of radiant energy |
October 4, 1977 |
| A method of and apparatus for measuring the wavelength of a source of radiant energy which includes passing split beams generated by such source along the same paths as those from a source of known wavelength and then comparing the number of interference fringes developed by the two sour |
