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Biotechnology Research and Development Corporation Patents
Assignee:
Biotechnology Research and Development Corporation
Address:
Peoria, IL
No. of patents:
34
Patents:




Patent Number Title Of Patent Date Issued
RE38028 Molecular genetic construction of vaccine strains of pasteurellaceae March 11, 2003
Tools for genetically engineering Pasteurellaceae are provided. Replication-conditional plasmids which are useful for the Pasteurellaceae have been isolated and characterized. The plasmids can be utilized for delivery of DNA segments into the Pasteurellaceae in situations where contr
7402419 Phosphite dehydrogenase mutants for nicotinamide cofactor regeneration July 22, 2008
Phosphite dehydrogenase mutant enzymes were generated that provide relaxed cofactor specificity and increased thermostability over the wild type enzyme. The mutant enzymes are useful for nicotinamide cofactor regeneration.
7193072 Compositions to identify swine genetically resistant to F18 E. coli associated diseases March 20, 2007
The present invention provides non-invasive methods and compositions to differentiate, with a high level of sensitivity and specificity, swine that are genetically susceptible to diseases associated with F18 E. coli infection, from resistant swine. DNA polymorphisms in the swine alpha
6936262 LktA deletion mutant of P. haemolytica August 30, 2005
Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are
6632862 Biodegradable polymer compositions, methods for making same, and articles therefrom October 14, 2003
A polymer composition includes a first component being a hydroxy-functional polymer, a second component being a natural polymer and a third component being a thermoplastic polyester. The first component, second component and third component are compounded to form a polymer composition.
6630543 Method of making biodegradable polymer compositions October 7, 2003
A method of making a biodegradable polymer composition including the steps of providing a first component being either one of a thermoplastic poly(hydroxy ester ether) or a synthetic, hydroxy-functional polymer and providing a second component being a natural polymer. The method includes
6573093 Temperature sensitive plasmids of P. haemolytica June 3, 2003
Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are
6495145 LktA deletion mutant of P. haemolytica December 17, 2002
Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are
6423310 Biological coating with a protective and curative effect for the control of postharvest decay July 23, 2002
Novel methods and compositions are provided for the biocontrol of plant diseases by use of a biological coating that confers both a protective and a curative effect for the control of postharvest decay. The coating includes chitosan salts, an antagonistic microorganism, and a cation. A
6419922 Candida saitoana compositions for biocontrol of plant postharvest decay July 16, 2002
Novel methods and compositions are provided for the biocontrol of plant diseases, in particular diseases causing plant postharvest decay. The novel compositions are "biocontrol cocktails" that are combinations of antagonistic microorganisms and antifungal agents. Suitable microorganisms
6362256 Biodegradable polymer compositions, methods for making same and articles therefrom March 26, 2002
A polymer composition includes a first component being a hydroxy-functional polymer, a second component being a natural polymer and a third component being a thermoplastic polyester. The first component, second component and third component are compounded to form a polymer composition.
6355859 Interactions between genotype and diet in swine that prevent E. coli associated intestinal disea March 12, 2002
The present invention relates interactions between genotype and diet that are useful in the dietary control of intestinal disease. Compositions are related that are useful to differentiate, with a high level of sensitivity and specificity, swine that are genetically resistant to a reduce
6331303 LKTA deletion mutant of P. haemolytica December 18, 2001
Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are
6221661 Hairpin ribozymes April 24, 2001
A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an RNA catalyst according to the
6191196 Biodegradable polymer compositions, methods for making same and articles therefrom February 20, 2001
A polymer composition uncludes a first component being a hydroxy-functional polymer, a second component being a natural polymer and a third component being a thermoplastic polyester. The first component, second component and third component are compounded to form a polymer composition.
6054510 Biodegradable formed article April 25, 2000
Compositions of the invention include a hydroxy-functional polyester and a natural polymer. Articles can be made from such a composition so as to have sufficiently strong tensile strengths as to form disposable utensils or to have sufficient stretchability so as to form thin wrap films.
5955646 Chimeric regulatory regions and gene cassettes for expression of genes in plants September 21, 1999
Chimeric regulatory regions and gene cassettes based upon Agrobacterium tumefaciens opine sythase genes are provided for expressing foreign genes in plants. Various upstream activating sequences from opine synthase genes like the mannopine synthase and the octopine synthase genes are ope
5869339 HIV targeted hairpin ribozymes February 9, 1999
A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an RNA catalyst according to the
5866701 HIV targeted hairpin ribozymes February 2, 1999
A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an RNA catalyst according to the
5858785 HIV targeted ribozymes January 12, 1999
A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an RNA catalyst according to the
5858666 Apparatus and method of detection employing an AC frequency sensor array January 12, 1999
A transducer for detecting biomolecules comprises a bottom and a top unit. The bottom unit has a set of parallel electrically conductive transmission lines thereon and probes attached to selected locations along each transmission line for binding with the target molecule. The top unit ha
5856188 Hairpin ribozymes January 5, 1999
A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an RNA catalyst according to the
5824525 Construction of Pasteurella haemolytica vaccines October 20, 1998
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect
5693777 DNA encoding pasteurella haemolytica PhaI restriction endonuclease and methyltransterase December 2, 1997
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect
5683900 Pasteurella haemolytica PhaI restriction endonuclcape and methyltranstesase November 4, 1997
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect
5674733 Method and materials for introducing DNA into Prevotella ruminicola October 7, 1997
A method of introducing expressible heterologous DNA into Prevotella ruminicola is provided. The method involves conjugal transfer of a shuttle vector comprising the heterologous DNA operatively linked to a promoter functional in P. ruminicola. The invention also provides shuttle vectors
5587305 Pasteurella haemolytica transformants December 24, 1996
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect
5581193 Multiple source and detection frequencies in detecting threshold phenomena associated with and/o December 3, 1996
Multiple frequency sources are used to apply a time varying signal to a scanning tunneling microscope and a current or voltage passing between the electrodes of the microscope is measured by a microwave spectrum/network analyzer which detects simultaneously at the multiple input frequenc
5559328 Small cavity analytical instruments September 24, 1996
A sample and the tip portion of an alternating current scanning tunneling microscope are electrically enclosed within a cavity with electrically conductive walls. The dimensions of the cavity are smaller than the wavelength of a component of the AC signal applied by the probe to the
5523083 Sprayabale gluten-based formulation for pest control June 4, 1996
The present invention provides a process of formulating a pest control agent into a sprayable gluten-based formulation. A gluten-based formulation for use in pest control is also provided. The present invention also provides a process of decreasing the population of a pest of a livin
5434842 Reading and writing stored information by means of electrochemistry July 18, 1995
By applying a voltage or signal and withdrawing or injecting an electron or electrons to a layer of material, it is possible to write, erase or read data electrochemically. The layer of material has at least one portion that will reversibly change between charge states in response to the
5322784 Method and materials for introducing DNA into Prevotella ruminicola June 21, 1994
A method of introducing expressible heterologous DNA into Prevotella ruminicola is provided. The method involves conjugal transfer of a shuttle vector comprising the heterologous DNA operatively linked to a promoter functional in P. ruminicola. The invention also provides shuttle vectors
5252466 Fusion proteins having a site for in vivo post-translation modification and methods of making an October 12, 1993
A hybrid DNA sequence encoding a fusion protein comprising: a first DNA sequence which encodes an amino acid sequence that allows for post-translation modification of the fusion protein; and a second DNA sequence joined end to end with the first DNA sequence and in the same reading f
5240842 Aerosol beam microinjector August 31, 1993
The present invention uses aerosol beam technology to accelerate either wet or dry aerosol particles to speeds enabling the particles to penetrate living cells. Aerosol particles suspended in an inert gas are accelerated to a very high velocity during the jet expansion of the gas as it p

 
 
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