| Patent Number |
Title Of Patent |
Date Issued |
| RE39031 |
RNA amplification method requiring only one manipulation step |
March 21, 2006 |
| An RNA amplification method is particularly useful for diagnosing bacterial or viral infections or genetic disorders and for cell typing. The method includes the steps of denaturing a solution containing RNA, synthesizing a first cDNA strand from a suitable primer in the presence of |
| D578654 |
Petri dish |
October 14, 2008 |
|
| 7626018 |
Enzymatic substrates derived from phenoxazinone and their use as developer in detection of micro |
December 1, 2009 |
| Novel enzymatic substrates of the general formula below: ##STR00001## reaction media containing the same and their use for detecting and/or identifying and/or quantifying microorganisms expressing at least one peptidase activity. |
| 7622249 |
Method for diagnosing and/or predicting of a septic syndrome |
November 24, 2009 |
| The present invention relates to a method for diagnosing and/or predicting a septic syndrome, wherein: a. a biological sample from the patient is made available and biological material is extracted from the biological sample b. at least four specific reagents which are selected from th |
| 7618790 |
Method for NGF assay for in vitro diagnosis of breast cancer and therapeutic use |
November 17, 2009 |
| The present invention concerns a method for the in vitro diagnosis of breast cancer which consists in determining the presence of NGF in a biological sample derived from a patient suspected of suffering from breast cancer. Said method may be used both in early diagnosis, screening, t |
| 7595180 |
RNA-dependent RNA polymerase functioning preferably on a RNA matrix and promoter-dependent trans |
September 29, 2009 |
| RNA may be transcribed using a nucleotide reagent as the promoter. The reagent may enable RNA to be transcribed without sequence specification and without protein cofactors, by means of an RNA polymerase that is known to be DNA-dependent such as the RNA polymerase of the phage T7, or |
| 7588909 |
Method for detecting Streptococcus agalactiae using .alpha.-glucosidase activity |
September 15, 2009 |
| The present invention concerns a method for specifically detecting and identifying Streptococcus agalactiae, using a reaction medium comprising at least one .alpha.-glucosidase enzymatic substrate. |
| 7587977 |
Pyrotechnic microsystem and method for fabricating a microsystem |
September 15, 2009 |
| The invention relates to a microsystem and a method for fabricating a microsystem. The pyrotechnic microsystem (7, 1') comprises a substrate having at least two separate electrical initiation zones, each of which provides separate electrical initiation of a pyrotechnic material depos |
| 7566530 |
Method for detecting PrP using at least one positive charge and/or at least one glycosidic bond |
July 28, 2009 |
| The invention relates to a method for detecting PrP in a biological human or animal sample that may contain PrP. The inventive method is characterised in that it uses a molecule containing at least one positive charge and/or at least one osidic bond and a ligand other than a proteini |
| 7553621 |
Reading, detection or quantification method, hybrids or complexes used in said method and the bi |
June 30, 2009 |
| The invention relates to a method of reading, detecting or quantifying at least one biological reaction, on a support, between either a recognition molecule and a labeled target molecule or between a target molecule and a labeled detection molecule. The inventive method comprises treatin |
| 7497135 |
Method for placing a receptacle containing a liquid in a device for sampling the liquid and samp |
March 3, 2009 |
| A method for placing a receptacle in a device for sampling liquid is described. It utilizes a device for sampling a liquid present in the receptacle, enabling the method of placing said receptacle to be applied. This method includes placing the receptacle, such as a bottle, having an |
| 7449341 |
Method and device for isolation and/or determination of an analyte |
November 11, 2008 |
| The invention concerns a method for isolating an analyte from an initial sample containing same, on a reactive surface in contact with all or part of the initial sample, characterized in that it comprises the following steps which consist in: 1) forming and/or maintaining a reaction volu |
| 7446186 |
Pyrroles substituted by oligonucleotides |
November 4, 2008 |
| The invention relates to novel pyrrole derivatives of the formula (I) which make it possible to immobilize and address oligonucleotides by electropolymerization. Said invention also relates to thus produced electroactive polymers and to methods for using them for detecting, identifyi |
| 7442550 |
Method for detecting the expression of an envelope protein of a human endogenous retrovirus and |
October 28, 2008 |
| A method for detecting the expression of a polypeptide in cells and for detecting the interaction between a polypeptide and cells, ex vivo or in vitro, wherein the polypeptide is selected from the group consisting of: a peptide comprising the cyt domain of the envelope protein of the hum |
| 7420054 |
Phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of |
September 2, 2008 |
| The present invention relates to novel enzymatic substrates with the following general formula: ##STR00001## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, A and X are as defined in claim 1, the reaction media comprising the same and the use thereof for the detection an |
| 7381817 |
LTR region of MSRV-1 and the proteins it encodes, and probes and methods for detecting MSRV-1 re |
June 3, 2008 |
| The invention relates to: a nucleotide fragment of an MSRV-1 LTR-RU5 region, comprising a nucleotide sequence encoding the expression of a protein, wherein the protein comprises a peptide sequence selected from the group consisting of: SEQ ID NO: 2, SEQ ID NO: 3, and SEQ ID NO: 4; co |
| 7368287 |
Use of L-.alpha.-lysophosphatidylcholine to obtain the differentiation of monocytes into mature |
May 6, 2008 |
| The present invention relates to the use of L-.alpha.-lysophosphatidylcholine and/or an equivalent compound for the differentiation of monocytes into mature denditric cell.The present invention also relates to a method for differentiation monocytes into mature denditric cells accordi |
| 7338805 |
Labeling reagents, methods for synthesizing such reagents and methods for detecting biological m |
March 4, 2008 |
| The present invention relates to a temperature-stable labeling reagent of formula: ##STR00001## in which R.sup.1 represents H or an alkyl, aryl or substituted aryl group, R.sup.2 represents a detectable marker or at least two detectable markers linked together by at least one multimer |
| 7335472 |
Method for simultaneously detecting hybridization reactions and immuno-reactions, and its uses i |
February 26, 2008 |
| The present invention relates to a method for simultaneously detecting hybridization reactions and immunoreactions in a sample which may contain target analytes consisting of at least one nucleic acid and of at least one other ligand that is different in nature, characterized in that it |
| 7301041 |
Bi-functional metallocenes, preparation process and use in the labeling or biological molecules |
November 27, 2007 |
| The invention relates to bi-functionalised metallocenes of general formula (I) where Me=a transition metal, preferably chosen from Fe, Ru and Os, Y and Z, when identical are selected from --(CH.sub.2).sub.n--O--, (CH.sub.2)--O--[(CH.sub.2).sub.2--O].sub.P-- and --(CH.sub.2).sub.q--CO |
| 7270059 |
Device for the electrical initiation of a pyrotechnic microcharge, and microsystem using such a |
September 18, 2007 |
| The invention relates to a device for the electrical initiation of at least one pyrotechnic microcharge (3), this device being characterized in that it comprises a support element having at least one conductive finger (6) connected to a first terminal of a central control unit (8), a sec |
| 7259021 |
Method for using a test card |
August 21, 2007 |
| The present invention relates to a method for using a test card (1) comprising at least one fluid circuit, constituting a network of channels (3) and/or of compartments (17), for transferring at least one biological liquid from at least one inlet (2) to at least one outlet (6, 17), and a |
| 7259012 |
Use of oxidized lipoproteins for differentiation of precursor cells into mature dendritic cells |
August 21, 2007 |
| The invention concerns a method for differentiating precursor cells into mature dendritic cells, comprising placing the precursor cells in a medium suitable for their differentiation and adding to the medium, in a predetermined amount, at least one fraction of oxidized lipoproteins s |
| 7235379 |
Method and medium for the detection/identification of microorgranisms with esterase activity |
June 26, 2007 |
| The invention relates to a method and a medium for microbiological analysis by biochemical means involving chromogenic or fluorogenic substrates that react with enzymes (esterases) specific for the target strains.One object of the invention is to improve the sensitivity, initial tran |
| 7226537 |
Method, device and apparatus for the wet separation of magnetic microparticles |
June 5, 2007 |
| Method for the wet dynamic separation of a suspension in liquid phase, comprising microparticles comprising a magnetic material and a liquid medium in which said microparticles are in suspension, in which method: a) the suspension is confined in a chamber having a volume defined by at |
| 7223865 |
Chromogenic compounds, and use thereof as enzyme substrates |
May 29, 2007 |
| The present invention relates to novel chromogenic substrates which are used to detect aminopeptidase activity in microorganisms or to determine whether at least one bacterium belongs to the Gram-positive group or to the Gram-negative group according to the color thereof. The invention |
| 7217536 |
Medium and method for detecting/identifying microorganisms |
May 15, 2007 |
| A medium for biological analysis by biochemical means involving chromogenic or fluorogenic substrates that react with enzymes (esterases and/or osidases and/or peptidases and/or sulfatases and/or phosphatases) specific for the target strains is that is in a stable, ready-to-use liqui |
| 7217457 |
Composite particles, derived conjugates, preparation method and applications |
May 15, 2007 |
| The invention relates to composite particles comprising a hydrophobic polymer core and inorganic nanoparticles. Said hydrophobic polymer forms a polymer matrix inside which the inorganic nanoparticles are stabilized and distributed in a relatively homogenous manner. Said particles are at |
| 7205362 |
Method for controlled radical polymerization |
April 17, 2007 |
| The present invention relates to a process for controlled radical polymerization using an organosulfur reversible chain transfer agent which consists in preparing polymers having a molar weight of greater than 100 000 g/mol, with a polydispersity index of less than 1.2 for molar weig |
| 7199215 |
Pseudopeptide, synthesis method, reagent and applications |
April 3, 2007 |
| The invention concerns a pseudopeptide of at least 6 amino acids comprising at least a unit selected among the general formulae (I) and/or (II) wherein: R.sub.1, R.sub.2 and R.sub.3 each independently of one another represent a side-chain of amino acids and can be identical or differ |
| 7179636 |
Preparing a sample to be analyzed from a sample with very large volume |
February 20, 2007 |
| The invention concerns the use of filtering means comprising a housing (2) wherein are arranged parallel to one another a plurality of hollow fibers (3), whereof the porous wall (3a) of each defines an aperture (4), so that said means comprises a inner path and an outer path (B) corr |
| 7141658 |
Single stranded oligonucleotides, probes, primers and method for detecting spirochetes |
November 28, 2006 |
| The invention concerns single stranded oligonucleotides comprising a sequence of at least 12 consecutive nucleotide motifs contained in one of the sequences SEQ ID NO: 1 to SEQ ID NO: 4 wherein "n" represents an identical or different nucleotide selected among inosine or an equimolar |
| 7134445 |
Double-effect pyrotechnic microactuator for microsystem and microsystem using same |
November 14, 2006 |
| The invention concerns the technical field of micro-actuators used for mechanical, chemical, electrical or thermal functions in microsystems, for microelectronic applications such as chips, or biomedical functions such as microfluidics integrating cards. The invention concerns a micr |
| 7132269 |
Coupling agents, the active intermediates and the conjugates thereof and the use of said conjuga |
November 7, 2006 |
| The present invention concerns coupling agents having the following general formula: ##STR00001## activated intermediates consisting of a coupling agent such as defined above with either a molecule having on its surface at least one aldehyde and/or ketone function before conjugation, |
| 7060804 |
Method for isolating proteins or protein and nucleic acid associations, or particle and protein |
June 13, 2006 |
| The invention concerns a method for isolating proteins and/or protein and nucleic acid associations in a sample, comprising steps which consist in: contacting said sample and magnetic colloidal particles comprising a core and a coat wherein: the core is magnetic and is coated with at lea |
| 7060441 |
Method for fragmenting and labeling DNA involving abasic sites and phosphate labeling |
June 13, 2006 |
| A single- or double-stranded deoxyribonucleic acid (DNA) is fragmented and labeled by chemically fragmenting the DNA by creating at least one abasic site on the DNA, and attaching a marker to at least one of the fragments by means of a labeling reagent, the reagent covalently and predomi |
| 7060438 |
Method for analyzing a patient's genetic prediposition to at least one disease and amplification |
June 13, 2006 |
| A patient's genetic predisposition to a disease may be analyzed by placing, in the presence of probes, at least one type of amplicon, derived from the amplification of at least one polymorphic region of nucleic acid from the patient. The polymorphic region is a polymorphic region of |
| 7029886 |
Enzymatic substrate, synthesis method and uses |
April 18, 2006 |
| The invention concerns novel enzymatic substrates of general formula (I) wherein: X represents a nitrogen atom or a carbon atom substituted with a phenyl group, said phenyl group being optionally substituted in meta or para position: Y and Z represent a hydrogen atom when X represents a |
| 7001589 |
Composite nanospheres and their conjugates with biomolecules |
February 21, 2006 |
| The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting |
| 7001572 |
Analyzing device with biochip |
February 21, 2006 |
| The invention concerns a device for analyzing at least an analyte, comprising a container and a biochip defining together at least a section, attached to the container by a suitable adhesive. The biochip comprises a support, for example polyhedral, comprising an active face including |
| 6964852 |
Antigenic structural peptide, antigenic and immunogenic compounds, and uses for detecting, preve |
November 15, 2005 |
| The invention concerns a structural peptide, identified by antibodies directed against a polypeptide, comprising the 2-45 amino acid sequence of the N-terminal end of the Core or nucleocapsid (p21) protein of the hepatitis C virus (HCV), excluding any protein or peptide compound comp |
| 6933110 |
Trypanosoma cruzi antigen, gene encoding therefor and methods of detecting and treating chagas d |
August 23, 2005 |
| The nucleotide sequence of Tc100, a gene encoding PTc100, a new Trypanosoma antigen, and the amino acid sequence of PTc100 are described. Tc100 and PTc100, or fragments thereof, modified or otherwise, can be used directly or indirectly for the detection of Trypanosoma cruzi, or for the |
| 6929918 |
Method for diagnosing an adenocarcinoma or a benign prostate pathology |
August 16, 2005 |
| The invention concerns a method for diagnosing a prostate adenocarcinoma in a male human patient without performing a prostatic biopsy, using the PSA protein (prostate specific antigen) present in the patient's blood, serum, urine or seminal fluid that involves measuring the free PSA tot |
| 6929239 |
Microfluid system for reactions and transfers |
August 16, 2005 |
| The invention concerns a device for performing a reaction or at least two reactions in parallel or in series, and for transferring a fluid flow, consisting of. an upper surface (2) and a lower surface (3) mutually linked by an edge (4); at least a duct (5) wherein a fluid flow (F1) can |
| 6921640 |
Process for labeling a ribonucleic acid |
July 26, 2005 |
| The present invention relates to a process for labeling a synthetic or natural ribonucleic acid (RNA). It also relates to RNA fragments, which have been labeled by fragmenting the RNA to free a terminal phosphate of each fragment for further reaction, and labeling each fragment at the |
| 6921635 |
Culture and identification media specific of different species of Candida and analysis methods |
July 26, 2005 |
| The invention concerns a culture and identification medium specific of yeasts comprising a chromogenous or fluorigenous substrate, capable of being hydrolyzed by an enzyme of the hexosaminidase and optionally glucosidase group, and/or at least a compound selectively inhibiting the he |
| 6902891 |
Process for labeling a nucleic acid |
June 7, 2005 |
| A process of fragmenting and labeling a synthetic or natural nucleic acid, comprising the steps of providing a mixture containing a nucleic acid, a labeling agent containing a detectable label, and at least one multivalent metal cation in a substantially aqueous solution; chemically frag |
| 6890720 |
Antigens derived from filaggrin and their use for diagnosing rheumatoid polyarthritis |
May 10, 2005 |
| The invention concerns an artificial antigen specifically identified by the anti-filaggrin autoantibodies present in the serum of patients suffering from rheumatoid polyarthritis, and consisting of one polypeptide comprising all or part of the sequence of one filaggrin unit or of a r |
| 6875858 |
Functionalized polynucleotide compound, optionally marked and method for detecting a target nucl |
April 5, 2005 |
| The invention relates to a functionalized compound of general formula (I): ##STR1## in which W represents a nucleotide analog, L represents a linker arm comprising at least four atoms, R.sub.1 represents a linear or branched alkyl chain,A functionalized polynucleotide comprising at l |
| 6866838 |
Composite nanospheres and their conjugates with biomolecules |
March 15, 2005 |
| The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously between 100 and 200 nm plus or minus 5%, and comprising an essentially liquid core consisting |
