| Patent Number |
Title Of Patent |
Date Issued |
| 7612880 |
Advanced polarization imaging method, apparatus, and computer program product for retinal imagin |
November 3, 2009 |
| A method, apparatus, and computer program product for identifying features in a sample by analyzing Mueller matrices to calculate an average degree of polarization, a weighted average degree of polarization, a degree of polarization map, a degree of polarization surface. Also, a method, |
| 7580582 |
Methods for decoding corrupt JPEG2000 codestreams |
August 25, 2009 |
| The present invention provides a method for decoding corrupt codestreams for encoded digital imagery and video and, in particular, JPEG2000 codestreams with improved error resilience properties. The decoding techniques apply to a class of coding algorithms in which the data from unde |
| 7492535 |
Multimodal miniature microscope |
February 17, 2009 |
| Apparatus for receiving and positioning optical components. The apparatus includes a substrate, one or more mounting slots, and one or more springs. The one or more mounting slots are formed in the substrate, and each mounting slot includes a mounting slot wall. At least one of the m |
| 7420682 |
Sensor device for interference and plasmon-waveguide/interference spectroscopy |
September 2, 2008 |
| Methods for measuring a property of a sample material present at an interface of an emerging medium in a spectroscopic device include a sensor (10) featuring at least one dielectric member (14) disposed upon a entrant medium (12), with the dielectric member being of an optical thickn |
| 7405041 |
Methods for regulating transcription by targeting quadruplex DNA |
July 29, 2008 |
| Among the different intrastrand quadruplex structures that can arise from duplex DNA, it has been discovered that the nucleotide sequences (GGA).sub.4 (SEQ ID NO: 1) and (GGA).sub.3GG (SEQ ID NO: 2) form biologically significant quadruplex structures. Thus, provided herein are method |
| 7335679 |
Wortmannin analogs and methods of using same |
February 26, 2008 |
| Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well as tumor formation in a subject are described herein. |
| 7335662 |
Substituted tricyclic compounds as protein kinase inhibitors |
February 26, 2008 |
| Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: ##STR00001## including steroisomers, prodrugs and pharmaceutically acceptable salts |
| 7326713 |
Substituted tricyclic compound as protein kinase inhibitors |
February 5, 2008 |
| Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: ##STR00001## including steroisomers, prodrugs and pharmaceutically acceptable salts |
| 7326712 |
Substituted tricyclic compounds as protein kinase inhibitors |
February 5, 2008 |
| Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: ##STR00001## including steroisomers, prodrugs and pharmaceutically acceptable salts |
| 7323174 |
Modulation of immune response and methods based thereon |
January 29, 2008 |
| The present invention relates to methods for the prevention and/or treatment of cardiovascular and allergic diseases and disorders, methods for inhibiting the growth of, or reducing the volume of, a solid tumor, as well as methods for preventing progression to AIDS in an HIV-infected |
| 7312226 |
Substituted tricyclic compounds as protein kinase inhibitors |
December 25, 2007 |
| Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure: ##STR00001## including steroisomers, prodrugs and pharmaceutically acceptable salts |
| 7256280 |
Cell cycle nucleic acids, polypeptides and uses thereof |
August 14, 2007 |
| The invention provides isolated nucleic acids and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and c |
| 7238800 |
Peptides and DNA encoding the peptides useful for immunizations against Coccidioides spp. infect |
July 3, 2007 |
| The present invention provides compositions of peptides and polynucleotides encoding the peptides, which peptides are useful for generating an immunological response in an individual and in therapeutic and diagnostic applications of infections due to pathogenic Coccidioides spp. fung |
| 7217739 |
Method for inducing cell death with carbonyl scavengers |
May 15, 2007 |
| Carbonyl scavengers, which have been recognized for their ability to react with reactive carbonyl species, have been implicated as agents that can accelerate or induce the death of abnormal cells without having a parallel effect on normal cells. As such, they are useful therapeutic a |
| 7153843 |
Inhibitors of phosphatidyl myo-inositol cycle |
December 26, 2006 |
| The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as anti-tumor 5 agents which effect |
| 7029838 |
Prevascularized contructs for implantation to provide blood perfusion |
April 18, 2006 |
| This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. T |
| 7022712 |
Solubilization of weak bases |
April 4, 2006 |
| A pharmaceutical composition for administration to mammals comprising: a weak base compound having a compound pKa below about 7; an acidic buffer with a buffer pKa below 7; and optional pharmaceutically acceptable additives, wherein the composition has a pH below about 4 is provided. |
| 6989153 |
Radiation sensitive liposomes |
January 24, 2006 |
| The present invention relates to a radiation sensitive liposome, and the use of this liposome as carrier for therapeutic and diagnostic agent(s). In particular, the invention encompasses a liposomal delivery system, comprising a stable liposome-forming lipid and a polymerizable colipid, |
| 6703414 |
Device and method for treating restenosis |
March 9, 2004 |
| A method of inhibiting restenosis in a subject following coronary angioplasty, atherectomy, or arterial bypass graft surgery comprised of administering wortmannin analogs of the present invention is described herein. |
| 6667340 |
Inhibitors of phosphatidyl myo-inositol cycle |
December 23, 2003 |
| The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as anti-tumor 5 agents which effect |
| 6653421 |
Photorefractive composition |
November 25, 2003 |
| A photorefractive compositions of the present invention includes a copolymer component that provides both photoconductive (charge transport) ability and non-linear optical ability, and optionally sensitizer and plasticizer components. Both of the photoconductive and non-linear optical |
| 6610809 |
Polymer, producing method thereof, and photorefractive composition |
August 26, 2003 |
| A photorefractive composition comprising a polymer prepared by living radical polymerization, wherein: the living radical polymerization is carried out using a monomer, a polymerization initiator, transition metal catalyst and a ligand capable of reversibly forming a complex with the |
| 6577584 |
Method and apparatus for detecting light from a multilayered object |
June 10, 2003 |
| An apparatus and method for reproducing signals from a multi-layer structured recording object wherein a linearly polarized laser beam illuminate the multi-layer structured object, such as a phase change recording medium via an objective lens system having an effective numerical aper |
| 6525466 |
Cathode including a mixture of a metal and an insulator for organic devices and method of making |
February 25, 2003 |
| An organic device including an organic layer of organic material; and a cathode in contact with the organic layer and including a mixture of a metal and an insulator. The mixture can be an alloy or a composite of the metal and insulator, and can be for example a mixture of Al:LiF or Al:C |
| 6323020 |
Neutralization-sensitive epitopes of Cryptosporidium parvum |
November 27, 2001 |
| DNA sequences encoding epitopes to which sporozoite-neutralizing antibodies are directed are provided. Recombinant proteins and synthetic peptides containing Cryptosporidium parvum epitopes for inducing, an antigenic response are described. |
| 6303311 |
Tethered function assay for protein function |
October 16, 2001 |
| A method for determining the function of a test protein is disclosed. In a preferred embodiment, this method comprises the steps of fusing a test protein to an RNA-binding protein and exposing the fusion protein to recombinant reporter mRNA molecule that comprises a binding site for the |
| 6087563 |
Cloned arabidopsis p-hydroxyphenyl pyruvic acid dioxygenase DNA |
July 11, 2000 |
| A cDNA clone from Arabidopsis thaliana, pHPP1.5, SEQ ID NO:1, which encodes the enzyme p-hydroxyphenyl pyruvic acid dioxygenase, is disclosed. A vector and microbial host containing a DNA sequence coding for the expression of Arabidopsis thaliana p-hydroxyphenyl pyruvic acid dioxygen |
| 5965267 |
Method for producing encapsulated nanoparticles and carbon nanotubes using catalytic disproporti |
October 12, 1999 |
| A method for the production of carbon encapsulated nanoparticles, carbon nanotubes and other closed carbon structures, including contacting a catalyst of a transition metal, or a compound or alloy thereof, with a gas mixture containing carbon monoxide, and an amount of available molecula |
| 5957972 |
Implants possessing a surface of endothelial cells genetically-modified to inhibit intimal thick |
September 28, 1999 |
| Autologous and synthetic vascular implants that possess an external monolayer of endothelial cells genetically modified to express at least one of a number of therapeutic agents useful for the inhibition of smooth muscle cell proliferation are provided. In the preferred embodiment of |
| 5928143 |
Implantable multi-electrode microdrive array |
July 27, 1999 |
| An apparatus is provided for use in neurophysiological research in general, and, in particular, for use on conscious, freely moving animals and on in vitro tissue samples. An array of elongated guide cannulae have lower ends which are parallel with and adjacent each other and upper ends |
| 5911990 |
T-cell receptor peptides and methods for preventing the progression to AIDS in an animal model |
June 15, 1999 |
| A novel peptide from the T-cell receptor is shown to be effective in preventing the progression to AIDS in an animal model. Methods for delaying the progression to AIDS and restoring normal immunological responses in an animal model following infection are shown and comprise administ |
| 5906984 |
Methods of using aminothiols to promote hematopoietic progenitor cell growth |
May 25, 1999 |
| The present invention relates to methods of stimulating he growth of hematopoietic progenitor cells. In particular, it relates to the use of thiols and related compounds in stimulating the growth of hematopoietic progenitor cells in vitro and in vivo. Furthermore, the present invention |
| 5866338 |
Cell cycle checkpoint genes |
February 2, 1999 |
| Human checkpoint huCDC34, huRAD9.sub.compA, and huRAD9.sub.compB cDNAs shown in FIGS. 1, 2, and 3. A method for isolating a human checkpoint cDNA that is capable of restoring growth at a restrictive temperature in a yeast test cell, wherein the yeast test cell comprises a genome having a |
| 5846958 |
Methods of using aminothiols to promote hematopoietic progenitor cell growth |
December 8, 1998 |
| The present invention relates to methods of stimulating the growth of hematopoietic progenitor cells. In particular, it relates to the use of thiols and related compounds in stimulating the growth of hematopoietic progenitor cells in vitro and in vivo. Furthermore, the present invention |
| 5780101 |
Method for producing encapsulated nanoparticles and carbon nanotubes using catalytic disproporti |
July 14, 1998 |
| A method for the production of carbon encapsulated nanoparticles, carbon nanotubes and other closed carbon structures, including contacting a catalyst of a transition metal, or a compound or alloy thereof, with a gas mixture containing carbon monoxide, and an amount of available molecula |
| 5767090 |
Microbially produced rhamnolipids (biosurfactants) for the control of plant pathogenic zoosporic |
June 16, 1998 |
| Disclosed is the use of biosurfactants as biological control products. In particular, rhamnolipid biosurfactants produced by Pseudomonas spp. were demonstrated to rapidly kill zoospores by rupturing the plasma membrane of three representative zoosporic plant pathogenic microorganisms: Py |
| 5753228 |
Method of treating parasitosis by the enteral administration of hyperimmune hen egg yolk antibod |
May 19, 1998 |
| Egg yolks and egg yolk fractions containing effective therapeutic concentrations of avian antibodies against parasitic antigen, and a method of providing passive immunization for the prevention or treatment of intestinal parasitosis by enteral administration of egg yolk antibodies ha |
| 5731408 |
Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
March 24, 1998 |
| Cyclic lactam peptides, seven amino acids in length, having D-2'-naphthylalanine (D-2'-Nal) or D-para-iodo-phenylalanine D-(p-I)Phe at position 4 of the peptide provided potent and specific antagonists of the two neural melanocortin receptors and of the peripheral receptor. In partic |
| 5674996 |
Cell cycle checkpoint genes |
October 7, 1997 |
| Human checkpoint huCDC34, huRAD9.sub.compA, and huRAD9.sub.compB cDNAs shown in SEQ ID Nos:7-9. A method for isolating a human checkpoint cDNA that is capable of restoring growth at a restrictive temperature in a yeast test cell, wherein the yeast test cell comprises a genome having a |
| 5651943 |
Apparatus and method for random polymer synthesis |
July 29, 1997 |
| An apparatus and method are provided for the synthesis of compounds, e.g., oligomers or polymers, by the repeated steps of coupling various subunits onto solid supports. The apparatus has for a first member a vessel having chambers opening to a surface of the member, and has for a second |
| 5648593 |
Stress tolerant pyrethrum plants |
July 15, 1997 |
| New and distinct varieties of Chrysanthemum cinerariaefolium plants exhibit environmental stress tolerance over a temperature range extending as low as about 17.degree. F. and as high as about 115.degree. F., and are also capable of producing flowers having an endogenous pyrethrin conten |
| 5637544 |
Reactive membrane for filtration and purification of gases of impurities and method utilizing th |
June 10, 1997 |
| A reactive membrane for removing impurities, such as water, oxygen and organic compounds, from a gas is provided. The reactive membrane includes a porous inorganic substrate having exposed surfaces and at least one carbon layer, which is modified to present active sites, deposited on the |
| 5635148 |
Reactive membrane for filtration and purification of gases of impurities and method utilizing th |
June 3, 1997 |
| A reactive membrane for removing impurities, such as water, oxygen and organic compounds, from a gas is provided. The reactive membrane includes a porous inorganic substrate having exposed surfaces and at least one carbon layer, which is modified to present active sites, deposited on the |
| 5339039 |
Langmuir probe system for radio frequency excited plasma processing system |
August 16, 1994 |
| A Langmuir probe system for measuring plasma internal discharge parameters in a radio frequency excited plasma processing system includes an electrically tuned resonant circuit. The electrically tuned resonant circuit includes a semiconductor variable capacitor. Specifically, an indu |
| 5326751 |
Enkephalin analogs |
July 5, 1994 |
| A new class of opioid receptor analogs is described based on an alanine substitution in the three position in the enkephalin analog DPDPE. The alanine-substituted analogs show increased selectivity for the delta type of opioid receptors over the mu type of receptors. |