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American Red Cross Patents
Assignee:
American Red Cross
Address:
Rockville, MD
No. of patents:
10
Patents:












Patent Number Title Of Patent Date Issued
7419948 Treatment of hemophilia with human Factor IX produced in mammary tissue of transgenic mammals September 2, 2008
Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention. Transgenic animals of the present invention are produced by introducing into develo
6984772 Transgenic non-human mammals producing fibrinogen in their milk January 10, 2006
A transgenic, non-human mammalian animal is capable of expressing a heterologous gene for human or other recombinant physiologically functional fibrinogen holoprotein or individual subunit chain polypeptides thereof or a modified or fusion fibrinogen in mammary glands of the animals
6838281 Cells expressing fusion proteins of immunoglobulins January 4, 2005
The invention provides methods and compositions for inducing and maintaining tolerance to epitopes or antigens containing the epitopes. The compositions include expression cassettes and vectors including DNA sequences coding for a fusion immunoglobulin operably linked to transcriptio
6344596 Expression of active human factor IX in mammary tissue and of milk non human transgenic mammals February 5, 2002
Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention. Transgenic animals of the present invention are produced by introducing into develo
6262336 Expression of a heterologous protein C in mammary tissue of transgenic animals using a long whey July 17, 2001
An isolated DNA sequence which regulates the expression of a heterologous gene composed of a mouse whey acidic protein promoter having a length of greater than about 2.4 kb extending upstream from the unique KpnI site in the mouse whey acidic protein gene is disclosed. Specifically a mou
6191260 Brain-associated inhibitor of tissue-type plasminogen activator February 20, 2001
The present invention relates to a novel BAIT protein which is a member of serpin superfamily which is expressed primarily in brain tissue. In particular, isolated nucleic acid molecules are provided encoding the human BAIT protein. BAIT polypeptides are also provided as are vectors,
5965789 Engineering protein posttranslational modification by PACE/furin in transgenic non-human mammals October 12, 1999
The invention relates to transgenic non-human multicellular organisms that contain polynucleotides for expressing proteins that alter posttranslational modification. In particular, the invention provides multiply-transgenic animals in which a first transgene encodes a first protein,
5589604 Expression of human protein C in mammary tissue of transgenic mammals December 31, 1996
Recombinant protein C characterized by a high percentage of active protein can be obtained in the milk of transgenic mammals that incorporate DNAs according to the present invention. Transgenic mammals of the present invention are produced by introducing into developing embryos DNA that
4961928 Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets October 9, 1990
The invention is a sterile, plasma-free storage medium for blood components including red blood cells and for platelets processed separately or together. The red cell storage medium includes a physiologically compatible, aqueous electrolyte solution. In one liter of this electrolyte
4695460 Synthetic, plasma-free, transfusible platelet storage medium September 22, 1987
The invention is a sterile, plasma-free platelet storage medium. The platelet storage medium includes a physiologically compatible, aqueous electrolyte solution. In one liter of this electrolyte solution there is between about 3.0 grams and about 7.5 grams of dextrose, between about 3.0

 
 
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