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American Home Products, Corp. Patents |
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Assignee: American Home Products, Corp.
Address: New York, NY
No. of patents: 84
Patents:
| Patent Number |
Title Of Patent |
Date Issued |
| D275788 |
Diagnostic test device |
October 2, 1984 |
|
| D269949 |
Container for a liquid or a gel |
August 2, 1983 |
|
| D260607 |
Container for liquid |
September 8, 1981 |
|
| D259662 |
Tourniquet and vein delineator |
June 23, 1981 |
|
| D257171 |
Combined electric shocking device for personal protection and guard therefor or the like |
September 30, 1980 |
|
| D257126 |
Pharmaceutical dispensing container or the like |
September 30, 1980 |
|
| D254477 |
Combined bottle and squeegee |
March 18, 1980 |
|
| D253127 |
Necropsy board for small animals |
October 9, 1979 |
|
| D253126 |
Necropsy board for small animals |
October 9, 1979 |
|
| D252106 |
Necropsy board for large animals |
June 12, 1979 |
|
| D252105 |
Necropsy board for large animals |
June 12, 1979 |
|
| D249641 |
Dispensing container or the like |
September 26, 1978 |
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| D249157 |
Deodorant container or the like |
August 29, 1978 |
|
| 6787319 |
.beta.-amyloid peptide-binding proteins and polynucleotides encoding the same |
September 7, 2004 |
| Novel proteins which bind human .beta.-amyloid peptide, polynucleotides which encode these proteins, and methods for producing these proteins are provided. Diagnostic, therapeutic, and screening methods employing the polynucleotides and polypeptides of the present invention are also |
| 6559127 |
Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
May 6, 2003 |
| Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheime |
| 6492421 |
Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4 |
December 10, 2002 |
| Disclosed are compounds which bind VLA-4. Certain of these compounds aslo inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheime |
| 6423688 |
Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4 |
July 23, 2002 |
| Disclosed are compounds which bind VLA-4. Certain of these compounds aslo inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheime |
| 6403617 |
Diaminopyridine-containing thiourea inhibitors of herpes viruses |
June 11, 2002 |
| Compounds of the formula ##STR1##Useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, humanherpesviruses-6 and -7, and Kaposi herpesvirus. |
| 6369197 |
Potassium channel interactors and uses therefor |
April 9, 2002 |
| The invention provides isolated nucleic acids molecules, designated PCIP nucleic acid molecules, which encode proteins that bind potassium channels and modulate potassium channel mediated activities. The invention also provides antisense nucleic acid molecules, recombinant expression vec |
| 6333167 |
Methods and reagents for identifying inhibitors of proteolysis of membrane-associated proteins |
December 25, 2001 |
| The present disclosure provides DNA constructs, genetically modified host cells and methods for identifying inhibitors of proteolysis of membrane-associated protease substrates including, but not limited to, amyloid precursor protein, a Notch protein and sterol response element bindi |
| 6313126 |
Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression |
November 6, 2001 |
| Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise ##STR1##Wherein:R.sub.1, R.sub.2 and R.sub.3 are each, independently, hydrogen, halogen, CF.sub.3, alkyl, alkoxy, MeSO.sub.2, or together can form a 5-7 membered carb |
| 6313114 |
3,4-Dihydro-2H-benzo[1,4]oxazinyl-methyl)-[3-(1H-indol-3yl)-alkyl]- amines |
November 6, 2001 |
| Compounds are provided which have the following formula: ##STR1##wherein:R is hydrogen, alkyl of 1 to 6 carbon atoms, phenyl, or substituted phenyl;X and Y are each, independently, hydrogen, halogen, cyano, or alkoxy of 1 to 6 carbon atoms; andm is 1 to 5; ora pharmaceutically acceptable sal |
| 6310066 |
Antipsychotic indolyl derivatives |
October 30, 2001 |
| The present invention provides novel compounds of the general formula: ##STR1##wherein R.sub.1 and R.sub.2 are H, OH, F, Cl, Br, I, 1 to 6 carbon alkyl or alkenyl, 1 to 6 carbon alkoxy, aryl, OR.sub.5, nitro, amino, CF.sub.3 or R.sub.1 and R.sub.2 are taken together to form a fused ring |
| 6291683 |
N-arloxyethyl-alkylamines for the treatment of depression |
September 18, 2001 |
| Compounds useful for alleviating symptoms of depression are provided which have the following formula: ##STR1##wherein:R.sub.1 is hydrogen, lower alkyl or aryl;R.sub.2 is hydrogen, lower alkyl, phenyl or substituted phenyl;X and Y are each, independently, hydrogen, lower alkyl, lower alkoxy, |
| 6291453 |
4-amino-phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4 |
September 18, 2001 |
| Disclosed are compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g., human, such as asthma, Alzheime |
| 6291434 |
Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation |
September 18, 2001 |
| This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure ##STR1##whereinX is ##STR2##R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9 and R.sup.10, are each, independently, hydrogen, acyl of 2-7 carbon at |
| 6258784 |
Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation |
July 10, 2001 |
| This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure ##STR1##whereinW is S, SO, SO.sub.2, NR;Y is O, S, NR, or CH.sub.2 ;R is hydrogen or alkyl of 1-6 carbon atoms, perfluoroalkyl of 1-6 carbon atoms, acyl of 2-7 carbon atoms, perfluoroacy |
| 6245799 |
[(Indol-3-yl)-cycloalkyl]-3-substituted azetidines for the treatment of central nervous system d |
June 12, 2001 |
| This invention provides novel compounds and pharmaceutical compositions and methods of using the compounds in the treatment of central nervous system disorders, such as anxiety and depression, the compounds having the formula I: ##STR1##wherein:X is N--R, O, S(O).sub.m ; m is 0 to 2; |
| 6245780 |
Tetrahydroisoquinolinyl-indole derivatives for the treatment of depression |
June 12, 2001 |
| Compounds are provided which have the formula: ##STR1##wherein:R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are, independently, hydrogen, halogen, alkoxy, or carboxamide;R.sub.5 is hydrogen, halogen, CF.sub.3, CN, carbamide or alkoxy; andX is (CH.sub.2).sub.n or a 4-6 membered carbocyclic ring, wh |
| 6239134 |
Diazole derivatives as serotonergic agents |
May 29, 2001 |
| The present invention provides compounds of the general formula (1): ##STR1##wherein:two atoms of X, Y, or Z are nitrogen and the third atom is sulfur or oxygen;R is H, halogen, OH, SH, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, C.sub.1 -C.sub.6 thioalkyl, phenoxy, thiophenoxy, phe |
| 6228880 |
4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists |
May 8, 2001 |
| Compounds having dopaminegic activity are provided, having the formula: ##STR1##wherein R.sup.1 and R.sup.2 are each, independently, hydrogen, C.sub.1-10 alkyl, or (CH.sub.2).sub.m R.sup.4, wherein R.sup.4 is phenyl or naphthyl which may be substituted by one or two substituents selected |
| 6221863 |
3,4-dihydro-2H-benzo[1,4]oxazine derivatives |
April 24, 2001 |
| Compounds are provided having the following formula: ##STR1##wherein:R.sub.1 is hydrogen or halogen;R.sub.2 is hydrogen, alkoxy or carboximide;R.sub.3 is hydrogen, alkyl, alkylaryl, aryl or substituted aryl;R.sub.4 is hydrogen, CN, halogen, or carboximide; andX is CH or N; or pharmaceutically ac |
| 6200994 |
1,4-Disubstituted cyclohexane derivatives for the treatment of depression |
March 13, 2001 |
| Compounds useful for the treatment of disorders of the serotonin-affected neurological systems are provided which have the following formula: ##STR1##wherein:X is carbon or nitrogen;R.sub.1 and R.sub.2 are each, independently, hydrogen, halogen, CF.sub.3, alkyl, alkoxy, or MeSO2.sub.4 ;R |
| 6168918 |
Method of detecting foreign DNA integrated in eukaryotic chromosomes |
January 2, 2001 |
| Methods of detecting the presence of a plasmid DNA sequence integrated in a chromosomal DNA molecule of a eukaryotic cell in a sample that contains chromosomal DNA molecules of eukaryotic cells and free plasmid DNA molecules are disclosed. According to the invention, chromosomal DNA of |
| 6162803 |
Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression |
December 19, 2000 |
| Compounds effective in treating disorders of the serotonin-affected neurological symptoms are provided, such compounds having the following formula: ##STR1## wherein: R.sub.1 and R.sub.5 are each, independently, hydrogen, halogen, lower alkoxy, lower alkyl, cyano, or trifluoromet |
| 6150533 |
N-aryloxyethyl-indoly-alkylamines for the treatment of depression |
November 21, 2000 |
| Compounds effective in treating disorders of the serotonin-affected neurological systems are provided, such compounds having the following formula: ##STR1## wherein: R.sub.1 is hydrogen, lower alkyl, phenyl, or substituted phenyl;X and Y together complete a lactam, imidazole, imidazo |
| 6140485 |
Nucleic acid encoding human neuronal calcium channel subunits |
October 31, 2000 |
| Nucleic acids encoding each of three subunits, .alpha.1B, .alpha.2.delta., and .beta.3, of a calcium channel, are disclosed. Also disclosed are vectors containing the nucleic acids encoding the subunits; host cells containing the nucleic acids encoding the subunits; methods of isolating |
| 6121307 |
N-aryloxyethyl-indoly-alkylamines for the treatment of depression |
September 19, 2000 |
| Compounds useful for alleviating symptoms of depression are provided which have the following formula: wherein:R.sub.1 is hydrogen, lower alkyl or aryl;R.sub.2 is hydrogen, lower alkyl, phenyl or substituted phenyl;X and Y are each, independently, hydrogen, lower alkyl, lower alkoxy, or halo |
| 6110956 |
N-aryloxyethylamine derivatives for the treatment of depression |
August 29, 2000 |
| Compounds effective in treating disorders of the serotonin-affected neurological systems are provided, such compounds having the following formula: ##STR1## wherein: R.sub.1 and R.sub.2 are each, independently, hydrogen, halogen, CF.sub.3, lower alkyl, lower alkoxy, MeSO.sub.2, o |
| 6049006 |
Elevation of HDL cholesterol by N-[2-[(aminothioxomethyl) hydrazono]-2-arylethyl]amides |
April 11, 2000 |
| This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of the formula ##STR1## wherein: R.sup.1, R.sup.2, and R.sup.3 are independently hydrogen, C.sub.1 -C.sub.6 alkyl or --(CH.sub.2).sub.0-6 Ph where Ph is |
| 5610154 |
Bicyclic carboxamides |
March 11, 1997 |
| Bicyclic carboxamides of formula I ##STR1## and the pharmaceutically acceptable acid addition salts are 5-HT.sub.1A binding agents, particularly 5-HT.sub.1A antagonists and may be used, for example, as anxiolytics. In the formulaX represents --CR.sup.2 .dbd.CR.sup.2 -- or --(CR.sup.2 |
| 5221745 |
Psychotropic piperidinylmethyl benzodioxans |
June 22, 1993 |
| The compounds ##STR1## in which Z is ##STR2## where R.sup.4 is -H or alkyl; q is one of the integers 0, 1 or 2; Y is H.sub.2 or O; or Z, taken with R.sup.1 forms ##STR3## R.sup.1 is hydrogen or alkyl or combined with Z as described above; R.sup.2 and R.sup.3 are, ind |
| 5010102 |
Anti-ulcer 5-(2-substituted ethenyl)-3(2H)-furanones |
April 23, 1991 |
| A compound of the formula: ##STR1## in which R is alkyl, phenyl or halophenyl; R.sup.2 is substituted phenyl having from 1 to 3 substiuents selected from halo, alkyl, alkylthio, alkylsulfonyl, cyano, trifluoromethyl, or R.sup.2 is pyridinyl, pyrazinyl, quinolinyl, N-alkylpyrrolyl |
| 4988814 |
Tertiary alkyl functionalized piperazine derivatives |
January 29, 1991 |
| Compounds of the formula: ##STR1## in which R.sup.1 is alkyl; R.sup.2 and R.sup.3 are alkyl or taken together they are polymethylene, R.sup.2 and R.sup.3 complete a 5-norbornen-2-yl moiety; X is --CO.sub.2 --, --OCO--, --OCO.sub.2 --, --N(R.sup.7)CO--, --NHNHCO--, --ON(R.sup.7)CO |
| 4957913 |
Antihypertensive polycyclic imides |
September 18, 1990 |
| Hypertension in the mammal is controlable by administration of a compound of the formula: ##STR1## wherein R is ##STR2## in which X is methylene, ethylene or ethylidene and Q is alkylene, alkylidene, or Q is a ##STR3## in which the dotted line represents optional uns |
| 4955481 |
Tablet package having alternative indicators and method of use |
September 11, 1990 |
| Packaging for a course of tablets comprises a base for a blister pack and a cover flap. Rub-off indicators are provided on the inner surface of the flap to permit indication of one of a range of alternatives related to the course. The indicators may be color keyed to particular doses of |
| 4933184 |
Menthol enhancement of transdermal drug delivery |
June 12, 1990 |
| Disclosed herein are compositions and methods for enhancing the transdermal delivery of physiologically active agents across mammalian skin or membranes and which comprise a percutaneous transfer enhancing amount of menthol and a drug. |
| 4931283 |
Menthol enhancement of transdermal drug delivery |
June 5, 1990 |
| Disclosed herein are compositions and methods for enhancing the transdermal delivery of physiologically active agents across mammalian skin or membranes and which comprise a percutaneous transfer enhancing amount of menthol and a drug. |
| 4904799 |
Preparation of tryptophols |
February 27, 1990 |
| Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1-, 4-, 5-, 6-, 7- and 8- are disclosed. The derivatives are useful anti-inflammatory and analgesic agents and methods for their preparation and |
| 4900739 |
Novel spirosuccinimides as aldose reductase inhibitors and antihyperglycemic agents |
February 13, 1990 |
| This invention relates to novel spirosuccinimide derivatives, to the processes for their preparation, to methods for using the compounds, and to pharmaceutical preparations thereof. The compounds have pharmaceutical properties which render them beneficial for the treatment of diabetes |
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