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Altana Pharma AG Patents
Assignee:
Altana Pharma AG
Address:
Konstanz, DE
No. of patents:
82
Patents:


1 2


Patent Number Title Of Patent Date Issued
6846821 Tetrahydrothiopy ranphthalazinone derivatives as PDE4 inhibitors January 25, 2005
The compounds of formula (I) in which R1, R2, A and Ar have the meanings as given in the description are novel effective PDE4 inhibitors. ##STR1##
6818651 (Dihydro) isoquinoline derivatives as phosphodiesterase inhibitors November 16, 2004
3,4-Dihydroisoquinoline and isoquinoline compounds of formula I, in which Ar represents a phenyl raidcal of the formulae IIa, IIb or IIc are novel effective PDE7 inhibitors.
6818642 Benzylaminopyrimidines November 16, 2004
Benzylaminopyrimidine compounds of a certain general formula I, in which the substituents and symbols are as defined in the description, are suitable for controlling Helicobacter bacteria.
6815557 Tryptase inhibitors November 9, 2004
Compounds of formula (I), in which M, A1, A2, K1 and K2 have the meanings as indicated in the description are novel active tryptase inhibitors.
6812349 Process and intermediates for the preparation of imidazopyridines November 2, 2004
The invention relates to compounds of formula (2) in which R1, R2, R3 and R4 have the meanings indicated in the description, their preparation and their further reaction to give compounds of formula (1), in which A.sub.1, A.sub.2 and R4 have the meanings indicated in the description. The
6787533 Process for R-epimer enrichment of 16,17-acetal derivatives of 21-acyloxy pregna,4-dien-11.beta. September 7, 2004
R-epimer enrichment of 16,17-acetal derivatives of 21-acyloxy pregna-1,4-dien-11beta,16alpha,17alpha-triol-3,20-dione derivatives is effected by fractional crystallization.
6780881 Freeze-dried pantoprazole preparation and pantoprazole injection August 24, 2004
Lyophilized pantoprazole preparations which are obtainable by freeze-drying of an aqueous solution of pantoprazole, ethylenediamine tetraacetic acid and/or a suitable salt thereof, and sodium hydroxide and/or sodium carbonate are disclosed. The preparations have advantageous properties
6767901 Ciclesonide contained pharmaceutical composition for application to mucosa July 27, 2004
The present invention provides a pharmaceutical composition for application to the mucosa to be used in drug therapy comprising a water-insoluble and/or water-low soluble substance, ciclesonide, and an aqueous medium, and having an osmotic pressure of less than 290 mOsm. This composition
6756371 Phthalazinone derivatives as PDE4 inhibitors June 29, 2004
The compounds of formula (I) in which R1, R2, A, B and Ar have the meanings as given in the description are novel effective PDe4 inhibitors ##STR1##
6737243 Determination of the hydrophobic pulmonary surfactant protein SP-C May 18, 2004
Methods for determining the strongly hydrophobic pulmonary surfactant protein SP-C, SP-C specific antibody and a reagent kit for carrying out the methods are described.
6716990 Process and intermediates for the preparation of imidazopyridines April 6, 2004
The invention relates to compounds of formula (2) in which R1, R2, R3 and R4 have the meanings indicated in the description, their preparation and their further reaction to give compounds of formula (1), in which A.sub.1, A.sub.2 and R4 have the meanings indicated in the description. The
6696461 Tricyclic imidazopyridines February 24, 2004
Compounds of formula (I) in which the substituents as defined in the description are useful for preventing and treating gastrointestinal disorders. ##STR1##
6686379 Salt form of pantoprazole February 3, 2004
The invention relates to the dihydrate of the magnesium salt of pantoprazole.
6673786 Tryptase inhibitors January 6, 2004
A compound of formula I ##STR1##in which M, A1, A2, A3, A4, A5, A6, B1, B2, B3, B4, B5, B6, K1, and K2 are defined herein and are novel effective tryptase-inhibitors.
6653477 Imidazopyridin-8-ones November 25, 2003
Compounds of formula (I), in which the substituents have the meanings mentioned in the description, are valuable intermediates for preparing active compounds for the prevention and treatment of gastrointestinal diseases. ##STR1##
6630483 Phenanthridine-N-oxides October 7, 2003
N-oxides of the compounds of formula (I) in which R1 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy or completely or predominantly fluorine-substituted 1-4C-alkoxy, R2 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy or completely or predominantl
6624181 Synergistic combination September 23, 2003
The invention relates to the combined administration of PDE inhibitors and .beta..sub.2 adrenoceptor agonists for the treatment of respiratory tract disorders.
6613769 Tryptase inhibitors September 2, 2003
The invention relates to bifunctional tryptase inhibitors of formula (I) ##STR1##wherein H1 and H2 comprise a Q group and L is a linker of formula ##STR2##and the conformation of the H1, H2 and L groups is such that the groups are separated by a distance of from 20 to 45 .ANG.. Pharmaceu
6607742 Suppository composition which is a spray-dried suspension of an acid-labile proton pump inhibito August 19, 2003
Acid-labile active compounds are prepared in suppository form, particularly for rectal administration.
6599752 Process for separating and analyzing hydrophobic proteins using thin layer chromatography July 29, 2003
This-layer chromatography is used to separate, identify and quantity hydrophobic protein, hydrophobic protein fragment, hydrophobic modified protein and hydrophobic peptide. A method is thus provided for determination of proteins and peptides which, due to their low solubility in an
6569453 Administration form comprising an acid-labile active compound May 27, 2003
An administration form for acid-labile active compounds are described. The administration forms have no enteric layers and are suitable for oral administration.
6544993 Tetrahydrothiopyranphthalazinone derivatives as PDE4 inhibitors April 8, 2003
The compounds of formula (I) in which R1, R2, A and Ar have the meanings as given in the description are novel effective PDE4 inhibitors. ##STR1##
6544250 Blind clinical trial device April 8, 2003
The present invention relates to a device for blinding the administration of nonsolid pharmaceutical presentations. The device is in particular an opaque container which has at least two attachments, one of which is intended for connection to a dispenser for the pharmaceutical presen
6538005 Phenanthridine-N-oxides with PDE-IV inhibiting activity March 25, 2003
The N-oxides of the compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, arm novel active bronchial therapeutics. ##STR1##
6534519 Phenanthridine-N-oxides with PDE-IV inhibiting activity March 18, 2003
The N-oxides of the compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are novel active bronchial therapeutics. ##STR1##
6534518 Polysubstituted 6-phenylphenanthridines with PDE-IV inhibiting activity March 18, 2003
Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and R6 have the meanings indicated in the description, are novel active bronchial therapeutics. ##STR1##
6531493 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-dichloropyrid-4-yl)benzamide in the treatment of m March 11, 2003
The invention relates to the novel use of 3-cyclopropylmethoxy-4-difluoromethoxy-N-(3,5-dichloropyrid-4-yl)benzamide , a pharmacologically tolerable salt thereof or its N-oxide in the treatment of multiple sclerosis.
6503923 Haloalkoxy imidazonaphthyridines January 7, 2003
Compounds of formula I ##STR1##in which R1, R2, R3, R4a, R4b, R5a, R5b, R6 and R7 have the meanings indicated in the specification, and their pharmacologically tolerable salts are useful for preventing and/or treating gastrointestinal diseases.
6498173 Synergistic combination comprising roflumilast and a pde-3 inhibitor December 24, 2002
Combinations of N-(3,5-dichloropyrid)-3-cyclopropylmethoxy-4-difluoromethoxybenzamide, its pharmacologically tolerable salts or its N-oxide, with PDE.sub.3 inhibitors, and methods of use thereof, are disclosed for therapeutic purposes.
6479514 Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity November 12, 2002
Compounds of formula (I) in which the substituents and symbols have the meanings indicated in the description, are suitable for the control of Helicobacter bacteria. ##STR1##
6479505 6-arylphenanthridines with PDE-IV inhibiting activity November 12, 2002
Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51 and Ar have the meanings indicated in the description, are novel active bronchial therapeutics. ##STR1##
6476025 Phenylphennanthridines with PDE-IV inhibiting activity November 5, 2002
Compounds of formula (I), in which R1, R2, R3, R31, R4, R5, R51, R6, R13 and R20 have the meaning indicated in the description, are novel active bronchial therapeutics ##STR1##
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