| Patent Number |
Title Of Patent |
Date Issued |
| 7524973 |
Nitrate esters of phenylaminothiophenacetic acid derivatives |
April 28, 2009 |
| The compounds of formula I ##STR00001## in which R1, R2, R3, R4 and R5 have the meanings as given in the description are novel effective antiinflammatory compounds. |
| 7468377 |
Imidazopyridine-derivatives as inductible no-synthase inhibitors |
December 23, 2008 |
| The compounds of Formula (I) ##STR00001## in which R1, R2, R3, R4, R5 and A have the meanings as given in the description are novel effective iNOS inhibitors. |
| 7393860 |
Tetrahydropyridoethers |
July 1, 2008 |
| The compound (7R,8R,9R)-2,3-Dimethyl-8-hydroxy-7-(2-methoxyethoxy)-9-phenyl-7,8,9,10-t- etrahydro-imidazo-[1,2-h] [1,7] naphthyridine inhibits the secretion of gastric acid. |
| 7390819 |
Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors |
June 24, 2008 |
| The compounds of formula I ##STR00001## in which R1, R2, R3 and A have the meanings as given in the description are novel effective INOS inhibitors. |
| 7329677 |
Imidazo(4,5-b)pyridine-derivatives as inducible no-synthase inhibitors |
February 12, 2008 |
| The compounds of formula (I) ##STR00001## in which R1, R2, R3, R4 and R11 have the meanings as given in the description are novel effective iNOS inhibitors. |
| 7326784 |
Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives |
February 5, 2008 |
| The invention relates to compounds of the formula 1, ##STR00001## in which R1, R2, R3, Arom and PG have the meanings as indicated in the description. These compounds are valuable intermediates for the preparation of pharmaceutically active compounds. |
| 7326718 |
8-Substituted imidazopyridines |
February 5, 2008 |
| The present invention relates to 8-substituted imidazopyridines of a certain formula (1) ##STR00001## in which the substitutents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protectiv |
| 7317021 |
Aminopyridine-derivatives as inductible no-synthase inhibitors |
January 8, 2008 |
| The compounds of Formula (I) ##STR00001## in which R1, R2, R3 and R4 have the meanings as given in the description are novel effective iNOS inhibitors. |
| 7314935 |
Tricyclic n-acyl compounds |
January 1, 2008 |
| The invention relates to compounds of the formula (1) where the substituents and symbols are as defined in the description. The compounds are valuable intermediates for preparing active pharmaceutical ingredients. |
| 7307084 |
Cyclic benzimidazoles |
December 11, 2007 |
| The invention relates to cyclic benzimidazoles of formula 1, ##STR00001## in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties. |
| 7256293 |
Imidazopyridine intermediates |
August 14, 2007 |
| The invention relates to compounds of the formula 1, ##STR00001## in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceutical active compounds. |
| 7247317 |
Compositions comprising phenylaminothiophenacetic acid derivatives for the treatment of acute or |
July 24, 2007 |
| Novel compositions for the treatment of IRDS and ARDS are indicated which contain a compound of formula (I), in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt of this compound and lung surfactant ##STR00001## |
| 7238664 |
Composition comprising a pulmonary surfactant and a PDE5 inhibitor for the treatment of lung dis |
July 3, 2007 |
| The invention relates to the combined administration of a pulmonary surfactant and a PDE5 inhibitor for the treatment of a disease in which pulmonary surfactant malfunction and/or phosphodiesterase 5 (PDE5) activity is detrimental. |
| 7223771 |
Tricyclic imidazopyridines |
May 29, 2007 |
| The invention provides compounds of the formula (I), in which the substituents and symbols are as defined in the description. The compounds inhibit the secretion of gastric acid. ##STR00001## |
| 7220746 |
Pyrrolidinedione substituted piperidine-phthalazones as PDE4 inhibitors |
May 22, 2007 |
| The compounds of formula I ##STR00001## in which the substituents have the meanings as indicated in the description, are novel effective PDE4 inhibitors. |
| 7202055 |
Process for the production of proteins and the production of arrays of proteins |
April 10, 2007 |
| Described is a novel process for the production of at least one protein of interest by secretion of the protein of interest from a pro- or eukaryotic host cell in a compartment system, which host cell is stably expressing a secretion system and capable of heterologous secretion of th |
| 7189736 |
Prodrugs of imidazopyridine derivatives |
March 13, 2007 |
| Compounds of formula 1, in which the substituents have the meanings mentioned in the description are suitable for the prevention and treatment of gastrointestinal diseases. ##STR00001## |
| 7186710 |
Phthalazinones |
March 6, 2007 |
| The compounds of formula I ##STR00001## in which R1, R2, R3, R4 and R5 have the meanings as given in the description are PDE4/7 inhibitors. |
| 7179810 |
Phthalazinone-piperidino-derivatives as PDE4 inhibitors |
February 20, 2007 |
| The compounds of formula I ##STR00001## in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors. |
| 7175854 |
Pharmaceutical preparation comprising an active dispersed on a matrix |
February 13, 2007 |
| The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation an active ingredient |
| 7173009 |
Surfactant protein C esters |
February 6, 2007 |
| Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described. |
| 7147869 |
Rapidly disintegrating tablet comprising an acid-labile active ingredient |
December 12, 2006 |
| A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutic |
| 7141567 |
Polysubstituted imidazopyridines as gastric secretion inhibitors |
November 28, 2006 |
| The invention relates to imidazopyridines of a certain formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion-inhibiting properties. |
| 7138399 |
Alkoxypyridine-derivatives |
November 21, 2006 |
| The compounds of formula I ##STR00001## in which R1 is 1 4C-alkoxy, A is 1 4C-alkylene, B represents 3H-imidazo[4,5-b]pyridin-2-yl, 3H-imidazo[4,5-b]pyridin-2-yl substituted by R2 and/or R3, 9H-purin-8-yl or 9H-purin-8-yl substituted by R4 and/or R5, are effective iNOS inhibitors. |
| 7135452 |
Recombinant SP-A for the treatment or prevention of pulmonary infection and inflammation |
November 14, 2006 |
| Recombinant surfactant protein A and pharmaceutical compositions based thereon are useful for the prevention or treatment of pulmonary infection and inflammation. |
| 7105676 |
Tetrahydropyridoethers |
September 12, 2006 |
| Compounds of formula (1) in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases. |
| 7101911 |
Tryptase inhibitors |
September 5, 2006 |
| Compounds of the formula I, in which M, A1, A2, K1 and K2 have the meanings given in the description are novel effective tryptase inhibitors. |
| 7060716 |
Tryptase inhibitors |
June 13, 2006 |
| Compounds of the formula (I), in which M is a central building block selected from the group below in which A1, A2, K1 and K2 are as defined in the description, are novel effective tryptase inhibitors. |
| 7056936 |
Synergistic combination |
June 6, 2006 |
| The invention relates to the combined administration of PDE inhibitors and .beta..sub.2 adrenoceptor agonists for the treatment of respiratory tract disorders. |
| 7053176 |
Combination of C1-INH and lung surfactant for the treatment of respiratory disorders |
May 30, 2006 |
| Pharmaceutical composition for the treatment of infant respiratory distress syndrome and acute lung injury (including adult respiratory distress syndrome) which contains C1 esterase inhibitor (C1-INH) and lung surfactant which comprises a lung surfactant protein. |
| 7041313 |
Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles |
May 9, 2006 |
| The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is provided with a film coating customary per se for sustained-release compositions. |
| 7034178 |
Process for the production of 3-phenylisoserine |
April 25, 2006 |
| This invention is drawn to a process for the production of (R,R)-phenylisoserine or a 1 4C-alkyl ester thereof. |
| 7022696 |
Piperazino-derivatives and their use as PDE4 inhibitor |
April 4, 2006 |
| The compounds of formula I ##STR00001## in which R1, R2, R3, A, X, s and R9 have the meanings as given in the description are novel effective PDE4 inhibitors. |
| 7022671 |
Surfactant protein C esters |
April 4, 2006 |
| Novel surfactant protein C esters suitable for preparing pharmaceutical compositions for the treatment of infant respiratory distress syndrome and adult respiratory distress syndrome are described. |
| 7015325 |
Tryptase inhibitors |
March 21, 2006 |
| Compounds of the formula (I), in which M, A1, A2, K1 and K2 have the meanings indicated in the description are novel active tryptase inhibitors. |
| 6998410 |
Compositions |
February 14, 2006 |
| Novel compositions for the treatment of IRDS and ARDS are indicated which contain N-(3,5-dichloro-pyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethox- ybenzamide and/or its pharmacologically tolerable salts and lung surfactant. |
| 6988619 |
Medicinal product package for eradication therapy |
January 24, 2006 |
| The object of the present invention is to provide a medicinal product package which is suitable for microbe eradication therapy and with which the patient's compliance is increased and thus the result of therapy is improved. |
| 6982075 |
Use of pulmonary surfactant |
January 3, 2006 |
| The invention describes the novel use of pulmonary surfactant preparations in the artificial respiration of patents with toxic oxygen concentrations. |
| 6962941 |
Tryptase inhibitors |
November 8, 2005 |
| The compounds of formula I ##STR1##in which M, B1, B2, R1, R2, R6, R7, K1 and K2 have the meanings as indicated in the description are novel active tryptase inhibitors. |
| 6960588 |
Tryptase inhibitors |
November 1, 2005 |
| Compounds of formula (I) ##STR1##in which M, B1, B2, B3, B4, B5, B6, A1, A2, A3, A4, A5, A6, K1 and K2 have the meanings as indicated in the description, are novel effective tryptase inhibitors. |
| 6953853 |
Phthalazinone-piperidino-derivatives as PDE4 inhibitors |
October 11, 2005 |
| The compounds of a formula I, in which the given substituents have the meanings as given in the description, are novel effective PDE4 inhibitors ##STR1## |
| 6936623 |
Pyrano[2,3-C]imidazo[-1,2-A]pyridine derivatives for the treatment of gastrointestinal disorders |
August 30, 2005 |
| Compounds of the formula (I), in which the substituents have the meanings mentioned in the description, are suitable for the prevention and treatment of gastrointestinal diseases. |
| 6936622 |
6-phenylbenzonaphthyridines |
August 30, 2005 |
| Compounds of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in the description, are novel effective PDE3/4 Inhibitors. |
| 6927292 |
Tricyclic epoxides |
August 9, 2005 |
| The invention relates to compounds of Formula (1), in which the substituents and symbols have the meanings indicated in the description. The compounds are valuable intermediates for the preparation of pharmaceutical active compounds. |
| 6924305 |
Diazocine derivatives and their use as tryptase inhibitors |
August 2, 2005 |
| Compounds of the formula I, in which B1, B2, R1, R2, R6, R7, K1 and K2 are as defined in the description are novel effective tryp-tase inhibitors. |
| 6916825 |
Alkylated imidazopyridine derivatives |
July 12, 2005 |
| Compounds of the formula 1 ##STR1##in which the substituents have the meanings mentioned in the description are suitable for the prevention and treatment of gastrointestinal diseases. |
| 6897229 |
Synergistic combination comprising roflumilast and a PDE-3 inhibitor |
May 24, 2005 |
| The PDE.sub.4 inhibitor N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxy benzamide, a pharmacologically tolerable salt or N-oxide thereof, in combination with a PDE.sub.3 inhibitor is disclosed for use in inhibiting bronchospasms and treating acute obstructive bronch |
| 6884802 |
6-heteroarylphenanthridines |
April 26, 2005 |
| Compounds of formula 1, in which Het is an unsubstituted or R6- and/or R7-substituted pyrrolyl, furanyl, thiophenyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, thiadiazolyl, pyrimidinyl, pyrazinyl or pyradazinyl radical, or an unsubstituted or R6- and/or R7 |
| 6869949 |
Polysubstituted imidazopyridines as gastric secretion inhibitors |
March 22, 2005 |
| The invention relates to imidazopyridines of a certain formula 1, in which the substituents and symbols have the meanings indicated in the description. The compounds have gastric secretion-inhibiting properties. |
| 6858223 |
Compositions comprising phenylaminothiophenacetic acid derivatives for the treatment of acute or |
February 22, 2005 |
| A composition comprising a combination of a compound of formula I ##STR1##in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt thereof, and lung surfactant is useful for treating patients afflicted with IRDS or ARDS. |
