| Patent Number |
Title Of Patent |
Date Issued |
| 7441894 |
Pseudo-accommodative IOL having diffractive zones with varying areas |
October 28, 2008 |
| In one aspect of the invention, a trifocal ophthalmic lens is disclosed that includes an optic having at least one optical surface, and a plurality of diffractive zones that are disposed on a portion of that surface about an optical axis of the optic. At least two of those diffractiv |
| 7400752 |
Video overlay system for surgical apparatus |
July 15, 2008 |
| An improved computer based surgical video overlay system that allows relevant surgical data from a surgical apparatus to be combined as a graphic image with the video image of a surgical procedure in which the data from the surgical apparatus is sent wireless to the video overlay con |
| 7285553 |
Serotonergic 5HT.sub.7 receptor compounds for treating ocular and CNS disorders |
October 23, 2007 |
| Compounds with 5HT.sub.7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, |
| 7220546 |
Methods for diagnosing glaucoma and discovering anti-glaucoma drugs |
May 22, 2007 |
| Methods for diagnosing glaucoma and for screening therapeutic agents for their usefulness in treating glaucoma are disclosed. |
| 7169767 |
Ophthalmic compositions containing galactomannan polymers and borate |
January 30, 2007 |
| The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic |
| 7060704 |
Serotonergic 5HT.sub.7 receptor compounds for treating ocular and CNS disorders |
June 13, 2006 |
| Compounds with 5HT.sub.7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, |
| 7045095 |
Use of low molecular weight amino alcohols in ophthalmic compositions |
May 16, 2006 |
| The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives. |
| 7005446 |
Use of AP-1 activators to treat glaucoma and ocular hypertension |
February 28, 2006 |
| Compositions comprising AP-1 activators and methods of use for treating glaucoma and ocular hypertension are disclosed. |
| 6960579 |
Serotonergic 5HT.sub.7 receptor compounds for treating ocular and CNS disorders |
November 1, 2005 |
| Compounds with 5HT.sub.7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, |
| 6949218 |
Use of low molecular weight amino alcohols in ophthalmic compositions |
September 27, 2005 |
| The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives. |
| 6916958 |
Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical comp |
July 12, 2005 |
| Aminobiguanides and the use of same as antimicrobial agents in pharmaceutical compositions are disclosed. The aminobiguanides are useful in the preservation of pharmaceutical compositions, particularly ophthalmic pharmaceutical compositions and compositions for treating contact lense |
| 6906077 |
Use of neurotrophic factor stimulators for the treatment of ophthalmic neurodegenerative disease |
June 14, 2005 |
| Compositions and methods for the treatment of retina and optic nerve head neuropathy are disclosed. The compositions and methods are particularly directed to the use of neurotrophic factor stimulators, such as AIT-082 (neotrofin), in the treatment of glaucomatous neuropathy. |
| 6860868 |
Surgical handpiece |
March 1, 2005 |
| A surgical handpiece having at least two lumens or tubes mounted to a body. At least one tube is used for aspiration and at least one other tube is used to inject heated surgical fluid for liquefying a cataractous lens. A portion of the second tube is enlarged to form a pumping chamber. |
| 6849253 |
Use of borate-polyol complexes in ophthalmic compositions |
February 1, 2005 |
| Water-soluble borate-polyol complexes are useful as buffers and/or antimicrobials in aqueous ophthalmic compositions, including those containing polyvinyl alcohol. These compositions have greater antimicrobial activity than comparable compositions containing typical borate buffers an |
| 6838449 |
Ophthalmic compositions containing galactomannan polymers and borate |
January 4, 2005 |
| The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic |
| 6723748 |
Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension |
April 20, 2004 |
| Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor. |
| 6680339 |
15-fluoro prostaglandins as ocular hypotensives |
January 20, 2004 |
| 15-fluoro substituted analogs of PGF.sub.2.alpha. and methods of their use in treating glaucoma and ocular hypertension are disclosed. |
| 6676628 |
Pumping chamber for a liquefracture handpiece |
January 13, 2004 |
| A surgical handpiece having at least two lumens or tubes mounted to a body. At least one tube is used for aspiration and at least one other tube is used to inject heated surgical fluid for liquefying a cataractous lens. A portion of the second tube is enlarged to form a pumping chamber. |
| 6664294 |
Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical comp |
December 16, 2003 |
| Aminobiguanides and the use of same as antimicrobial agents in pharmaceutical compositions are disclosed. The aminobiguanides are useful in the preservation of pharmaceutical compositions, particularly ophthalmic pharmaceutical compositions and compositions for treating contact lense |
| 6664286 |
Serotonergic 5ht2 agonists for treating glaucoma |
December 16, 2003 |
| Compounds with 5HT.sub.2 receptor agonist activity useful for treating glaucoma, including lowering intraocular pressure. Compositions and methods for their use are also disclosed. |
| 6649655 |
11.beta.-fluoro 15.beta.-hydroxy PGF2.alpha. analogs as FP receptor antagonists |
November 18, 2003 |
| Methods and compositions for the antagonism of FP receptor-mediated biological responses are disclosed. |
| 6649653 |
15-fluoro prostaglandins as ocular hypotensives |
November 18, 2003 |
| 15-Fluoro substituted analogs of PGF.sub.2.alpha. and methods of their use in treating glaucoma and ocular hypertension are disclosed. |
| 6648847 |
Method of operating a liquefracture handpiece |
November 18, 2003 |
| A surgical handpiece having at least two lumens or tubes mounted to a body. At least one tube is used for aspiration and at least one other tube is used to inject heated surgical fluid for liquefying a cataractous lens. A portion of the second tube is enlarged to form a pumping chamber. |
| 6646001 |
Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agon |
November 11, 2003 |
| Disclosed are methods and compositions for the treatment of glaucoma and ocular hypertension, comprising the administration of a prostaglandin FP receptor agonist and a prostaglandin synthesis inhibitor. |
| 6589204 |
Method of operating a liquefracture handpiece |
July 8, 2003 |
| A surgical handpiece having two coaxial tubes or channels mounted within a body. The first tube is used for aspiration and is smaller in diameter than the second tube so as to great an annular passage between the first and second tube. The annular passage communicates with a pumping cham |
| 6589201 |
Liquefracture handpiece tip |
July 8, 2003 |
| A surgical handpiece having two coaxial tubes or channels mounted within a body. The first tube is used for aspiration and is smaller in diameter than the second tube so as to create an annular passage between the first and second tube. The annular passage communicates with a pumping cha |
| 6583124 |
Ophthalmic compositions containing galactomannan polymers and borate |
June 24, 2003 |
| The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic |
| 6579270 |
Liquefracture handpiece tip |
June 17, 2003 |
| A surgical handpiece and tip having two coaxial tubes or channels mounted within a body. The first tube is used for aspiration and is smaller in diameter than the second tube so as to create an annular passage between the first and second tube. The annular passage communicates with a pum |
| 6575929 |
Pumping chamber for a liquefaction handpiece |
June 10, 2003 |
| A surgical handpiece having a tube used to inject heated surgical fluid for liquefying a cataractous lens. A portion of the tube is enlarged to form a pumping chamber. The pumping chamber works by boiling a small volume of the surgical fluid. As the fluid boils, it expands rapidly, there |
| 6545045 |
Prostaglandin E agonists for treatment of glaucoma |
April 8, 2003 |
| This application relates to compositions and methods for the treatment of glaucoma and/or ocular hypertension in mammals utilizing prostaglandin E receptor agonists. |
| 6541572 |
Method of making high refractive index ophthalmic device materials |
April 1, 2003 |
| Disclosed is a two-step method of making soft, high refractive index, acrylic ophthalmic device materials. In the first step, a copolymer containing pendant oxirane groups is formed by copolymerizing one or more aryl acrylic hydrophobic monomers with one or more compounds of the form |
| 6531614 |
Method of prostaglandin synthesis |
March 11, 2003 |
| Methods of synthesizing 9-Halo-13,14-dihydroprostaglandins useful in the treatment of glaucoma and ocular hypertension are disclosed. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins. |
| 6531480 |
Non-peptide bradykinin receptor antagonists for use in treating ophthalmic diseases and disorder |
March 11, 2003 |
| This invention relates to the topical ocular use of non-peptide bradykinin receptor antagonists for the treatment of human ocular pain, neovascularization, corneal haze, allergy and inflammatory diseases. |
| 6509327 |
Compositions and methods for treating otic, ophthalmic and nasal infections |
January 21, 2003 |
| Ophthalmic, otic and nasal compositions containing a new class of antibiotics (e.g., moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic, otic and nasal conditions by topicall |
| 6503497 |
Use of borate-polyol complexes in ophthalmic compositions |
January 7, 2003 |
| Water-soluble borate-polyol complexes are useful as buffers and/or antimicrobials in aqueous ophthalmic compositions, including those containing polyvinyl alcohol. These compositions have greater antimicrobial activity than comparable compositions containing typical borate buffers an |
| 6500831 |
Non-peptide bradykinin receptor antagonists for use in controlling intraocular pressure and trea |
December 31, 2002 |
| This invention relates to the topical ocular use of non-peptide bradykinin receptor antagonists to treat glaucoma and ocular hypertension. |
| 6495608 |
Methods of performing surgery with galactomannan polymers and borate |
December 17, 2002 |
| The present invention is directed to viscoelastic systems comprising a combination of a galactomannan polysaccharide containing composition and borate containing composition. The two compositions gel or partially gel upon combination. The present invention also discloses methods of using |
| 6492417 |
11-deoxy-16-fluoro-PGF2.alpha. analogs as FP receptor antagonists |
December 10, 2002 |
| Methods and compositions for the antagonism of FP receptor-mediated biological responses are disclosed. |
| 6491721 |
Toric intraocular lens material |
December 10, 2002 |
| A method of selecting an intraocular lens material for toric lenses is disclosed. The method comprises determining the tack of the material. |
| 6491661 |
Infusion control system |
December 10, 2002 |
| An infusion control system having a flexible, collapsible infusion container. The container can be compressed between rollers or plate so at to pressurize the container. Such a system allows for rapid pressure response rates without the need of venting devices or air filtering. The m |
| 6486215 |
Solutions for treating contact lenses |
November 26, 2002 |
| Contact lens care compositions for the treatment of hard contact lenses are disclosed. The compositions are useful for rinsing, cleaning, disinfecting and storing of hard contact lenses. The compositions contain an unique gelling system involving galactomannan polysaccharides and borates |
| 6486138 |
Ophthalmic compositions containing galactomannan polymers and borate |
November 26, 2002 |
| The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic |
| 6482230 |
Lens epithelial cell growth assay for intraocular lens materials |
November 19, 2002 |
| A method for determining the propensity of an intraocular lens material to prevent posterior capsule opacification is disclosed. The method involves contacting a sample of an IOL material having the shape of an IOL optic with collagen to form a contact area, incubating the sample in a li |
| 6462080 |
Prostaglandin E receptor agonists for treatment of dry eye |
October 8, 2002 |
| The present invention relates to use of prostaglandin E receptor agonists and partial agonists to stimulate mucin secretion to treat dry eye, keratoconjunctivitis, Sjogren's syndrome and related ocular surface diseases. |
| 6455318 |
Collagen IV adhesion assay for intraocular lens materials |
September 24, 2002 |
| A method for determining the propensity of an intraocular lens material to prevent posterior capsule opacification is disclosed. The method involves incubating replicate samples of an IOL material with collagen IV, washing off any loosely bound collagen IV. Following the washing step, on |
| 6444710 |
Use of certain fatty acid/amino acid soaps to enhance antimicrobial effectiveness of topically a |
September 3, 2002 |
| Fatty acid/amino acid soaps are used to enhance antimicrobial effectiveness in topically administrable pharmaceutical compositions containing at least one active ingredient, a cationic preservative and an anionic polyelectrolyte, such as a carboxyvinyl polymer, xanthan gum, polystyrene |
| 6441047 |
Combination therapy for treating glaucoma |
August 27, 2002 |
| Methods for treating persons with glaucoma or ocular hypertension with glutamate antagonists and IOP-lowering compounds are disclosed. |
| 6441033 |
11.beta.-fluoro 15.beta.-hydroxy PGF2.alpha. analogs as FP receptor antagonists |
August 27, 2002 |
| Methods and compositions for the antagonism of FP receptor-mediated biological responses are disclosed. |
| 6440964 |
Compositions and methods for treating ophthalmic and otic infections |
August 27, 2002 |
| Ophthalmic, otic and nasal compositions containing a new class of antibiotics (e.g., moxifloxacin) are disclosed. The compositions preferably also contain one or more anti-inflammatory agents. The compositions may be utilized to treat ophthalmic, otic and nasal conditions by topicall |
| 6433007 |
Methods for the prevention and treatment of post-surgical complications |
August 13, 2002 |
| Methods for treating post-surgical formation of cataracts or posterior capsule opacification are disclosed. The methods utilize compositions containing certain compounds having an anti-inflammatory and anti-oxidant moiety covalently linked by and amide and ester bond. |