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Aktiebolaget Leo Patents
Assignee:
Aktiebolaget Leo
Address:
Helsingborg, SW
No. of patents:
24
Patents:




Patent Number Title Of Patent Date Issued
RE29202 Secondary phosphoric acid esters May 3, 1977
Novel symmetrical secondary phosphoric acid esters having the general formula ##STR1## wherein the substituent R is positioned in meta or para position relative to the phosphoric acid ester group; processes for the preparation of said esters; and compositions containing said este
RE29199 Certain steroid N-bis-(haloethyl)-carbamates May 3, 1977
.Iadd.Antitumor active mono and poly N-Bis-(B-haloethyl)-carbamic acid esters of certain estrogenic steroid hormones, especially estradiol; such compounds wherein all hydroxyl groups of the steroid molecule are not thus esterified; and organic and inorganic acid esters of such latter
4936687 Mixing apparatus and method June 26, 1990
An apparatus for performing mixing in thin liquid layers containing a suspension of a multiplicity of movable particles of magnetic material. The apparatus includes at least two magnets or magnet systems, of which at least one is an electromagnet. the magnets or magnet systems are arrang
4927423 Connector and a disposable assembly utilizing said connector May 22, 1990
A disposable assembly comprises a drug container (2) having at one end an opening which is surrounded by an outwardly directed flange (7). A connector (1) has a sleeve (13) which is closed (14) at one end and open at its opposite end to receive the flanged end of the drug container as a
4871543 Intravaginal devices October 3, 1989
The invention concerns an intravaginal device comprising a combination of 17 .beta.-estradiol and a supporting matrix for treating hypoestrogenic women. The device releases continuously 17 .beta.-estradiol at a rate of about 0.5 to about 25 .mu.g/24 h.The invention also comprises a metho
4824678 Controlled-release medical preparations April 25, 1989
The present invention concerns a novel pharmaceutical preparation having a biphasic release pattern. The preparation comprises a tablet core containing a drug. The tablet is coated with a coating essentially consisting of a film-forming water-insoluble polymer having fine water solub
4654197 Cuvette for sampling and analysis March 31, 1987
Disposable cuvette for essentially simultaneous sampling of a fluid and analyzing the sample. The new cuvette comprises a body member having at least one cavity defined by surrounding walls, into which cavity the sample is permitted to enter by capillary force through an inlet commun
4613695 N-nitroso compounds and compositions containing such compounds September 23, 1986
The invention concerns N-nitroso compounds having the general formula: ##STR1## wherein A is lower alkyl or halolower alkyl;B is hydrogen; lower alkenyl; lower alkynyl; 3-6 C cycloalkyl; --RSO.sub.2 NR.sup.3 R.sup.4, or lower alkyl optionally monosubstituted with lower alkoxy, or 3-6
4592869 Selective acylation process June 3, 1986
This invention relates to a selective acylation process for the preparation of phenolic N-disubstituted carbamate esters of steroids, comprising reacting in an inert solvent an acylating agent being a carbamoyl halogenide, a 4-(tertiary amino)-pyridine, or a complex thereof, optional
4579858 Smoking substitutes for nasal administration-I April 1, 1986
A smoking substitute composition for application directly into the nose, consisting essentially of an aqueous solution of nicotine or a physiologically acceptable acid addition salt thereof, having a pH value of 2 to 6, containing 10 to 0.5% w/v of nicotine calculated as the free bas
4547511 Heterocyclic carboxamides, compositions containing such compounds, processes for their preparati October 15, 1985
This invention relates to novel heterocyclic carboxamides which increase the activity of the immune system and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds and methods of treatment therewith.
4249003 Process for polycyclic amines February 3, 1981
This invention relates to a new method for the preparation of amines containing alkylene groups by using cyclic alkylene sulphuric esters, and novel intermediates for use in the method.The new method is useful for preparation of i.a. pharmaceuticals. The novel intermediates are useful i.
4249002 Polycyclic amines and intermediates therefor February 3, 1981
This invention relates to a new method for the preparation of amines containing alkylene groups by using cyclic alkylene sulphuric esters, and novel intermediates for use in the method.The new method is useful for preparation of i.a. pharmaceuticals. The novel intermediates are useful i.
4082779 Acylation process for the preparation of steroid phenolic n-disubstituted carbamate esters, and April 4, 1978
This invention relates to a novel carbamoylation method for the preparation of steroid phenolic N-disubstituted carbamate esters, and novel compounds in said method. Phenolic carbamate esters are useful for various purposes, for instance as pharmaceuticals, e.g. antitumor agents, as bioc
4081461 Acylation process for the preparation of phenolic N-disubstituted carbamate esters, and ion pair March 28, 1978
This invention relates to a novel carbamoylation method for the preparation of phenolic N-disubstituted carbamate esters, and novel compounds in said method. Phenolic carbamate esters are useful for various purposes, for instance as pharmaceuticals, e.g. antitumor agents, as biocides, e.
4061747 Antidepressant composition December 6, 1977
This invention relates to novel solid compositions, e.g., tablets, pills, dispersible powders, granules, or capsules, containing as active ingredient the compound 4'-chloro-2-{[3-(10,11-dihydro-5H-dibenz(b,f)-azepinyl-(5)-propyl]-methyla mino}-acetophenone hydrochloride (in the follow
4055638 Novel compounds, compositions containing such compounds, processes for their preparation and met October 25, 1977
This invention relates to novel secondary phosphoric acid esters and salts thereof, having valuable pharmacological properties, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and methods of treatment the
4049800 Method, composition and compounds for treating excess prostaglandins September 20, 1977
This invention relates to novel secondary phosphoric acid esters and salts thereof, having valuable pharmacological properties, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and methods of treatment the
4049799 Method, composition and compounds for treating excess prostaglandins September 20, 1977
This invention relates to novel secondary phosphoric acid esters and salts thereof, having valuable pharmacological properties, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and methods of treatment the
4029778 Cortical steroid nitrogen mustard compositions and treatment therewith June 14, 1977
New 21-esters of corticoid steroid hormones, the esters having an antitumor activity, are prepared by reacting a reactive derivative of the general formula ##STR1## wherein R.sup.1 can be hydrogen, lower alkyl, halogen, or lower alkoxy, X can be oxygen, sulphur, or a monovalent c
3995033 Secondary phosphoric acid esters, composition and method of use November 30, 1976
This invention relates to novel secondary phosphoric acid esters and salts thereof, having valuable pharmacological properties, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and methods of treatment the
3991187 Medicinal compositions and methods of use involving phosphoric acid esters November 9, 1976
Novel symmetrical secondary phosphoric acid esters having the general formula ##SPC1##Wherein the substituent R is positioned in meta or para position relative to the phosphoric acid ester group; processes for the preparation of said esters; and compositions containing said esters. T
3989825 Secondary phosphoric acid esters November 2, 1976
This invention relates to novel secondary phosphoric acid esters and salts thereof, having valuable pharmacological properties, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing the said compounds, and methods of treatment the
3963707 Novel N-nitroso compounds, compositions containing such compounds, processes for their preparati June 15, 1976
This invention relates to novel N-halogenoalkyl-N-nitroso carbamates and N.sup.4 halogenalkyl-N.sup.4 -nitroso allophanates of steroid compounds, having an anti-tumor activity, and to the preparation thereof. The invention is also concerned with pharmaceutical compositions containing

 
 
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