| Patent Number |
Title Of Patent |
Date Issued |
| D314051 |
Drug release valve for a parenteral administration system |
January 22, 1991 |
|
| D285904 |
Bottle for fluid medicines |
September 30, 1986 |
|
| 5441968 |
Therapeutically active fluoro substituted benzimidazoles |
August 15, 1995 |
| The novel compounds of the formulas I and I' ##STR1## wherein F is in 5 or 6 position and ##STR2## wherein in both formulas R is the group --CH.sub.2 OCOOR.sup.1, wherein R.sup.1 is a straight or branched alkyl containing 1-6 carbon atoms or benzyl, or R.sup.1 is the group |
| 5274099 |
Therapeutically active fluoro substituted benzimidazoles |
December 28, 1993 |
| The novel compounds of the formulas I and I' ##STR1## wherein F is in 5 or 6 position and ##STR2## wherein in both formulas R is the group --CH.sub.2 OCOOR.sup.1, wherein R.sup.1 is a straight or branched alkyl containing 1-6 carbon atoms or benzyl, or R.sup.1 is the group -- |
| 5270056 |
Particle having a dyed coke indicator and a pharmaceutical coating for parenteral administration |
December 14, 1993 |
| A particle containing a liquid-soluble active substance for release outside a human or animal body, said particle comprising a core with a coating thereon, said coating comprising a liquid soluble active substance, is characterized in that the core has an appearance differing from the |
| 5246714 |
Drug preparation |
September 21, 1993 |
| Controlled release preparation containing a number of insoluble beads applied with one or more pharmaceutically active compounds, a method for the production thereof and the use in a treatment where a controlled release of a pharmaceutically active compound is needed. |
| 5215974 |
Certain pyridyl[(methylthio- or methyl sulfinyl)-2 benzimidazol-2-yl]N-methyl phosphonates usefu |
June 1, 1993 |
| Novel compounds of the formula ##STR1## pharmaceutical compositions containing such compounds as active ingredient, and the use of the compounds in medicine for treating gastric acid related diseases such as gastritis, gastric ulcer, duodenal ulcer and reflux esophagitis. |
| 5201705 |
Device for release of a substance |
April 13, 1993 |
| A device for release of a solid substance into a flowing liquid during parenteral administration of the liquid to a patient includes a connector (1, with an inlet (6) and an outlet (12) for the liquid, and a valve assembly (4,5). The valve assembly has a valve core (5) which is rotatable |
| 5149523 |
Polystyrenesulfonate-drug complex and solid dosage forms thereof |
September 22, 1992 |
| Almokalant (p-INN), 4-[3-]ethyl[3-(propylsulfinyl)propyl]amino[-2-hydroxypropoxy]-benzonitrile , having the formula ##STR1## is a member of a group of compounds useful in the treatment of cardiac arrhythmias. Enhanced stability, palatability, and technical properties of almoka |
| 5106862 |
Derivatives of benzimidazoles active as anti-ulcer agents |
April 21, 1992 |
| Novel compounds of the general formula I ##STR1## processes for its preparation, pharmaceutical compositions containing such compounds as the active ingredient and the use of the compounds in medicine. |
| 5093342 |
Use of omeprazole as an antimicrobial agent |
March 3, 1992 |
| Use of 5-methoxy-2[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-sulfinyl]-1H-benz imidazole or a pharmaceutically acceptable salt thereof in the treatment of infectious diseases, especially such caused by Campylobacter pylori. |
| 5081154 |
Metoprolol succinate |
January 14, 1992 |
| The present invention relates to metoprolol succinate, a new therapeutically active compound, and pharmaceutical preparations comprising this new compound. |
| 5075323 |
Compounds including omeprazole in the treatment of glaucoma |
December 24, 1991 |
| A method for the treatment of diseases related to an increased intraocular pressure in the eye comprising administration to a patient suffering therefrom an amount of a compound of the formula I ##STR1## or a pharmaceutically acceptable salt thereof. |
| 5068272 |
Novel polystyrenesulfonate, useful against cardiac arrhythmias |
November 26, 1991 |
| A salt of 4-[3-[3-[ethyl-[3-(propylsulfinyl)propyl]amino]-2-hydroxyproproxy]-benzoni trile having the formula I ##STR1## with polystyrenesulponic acid, which is useful for the treatment of cardiac arrhythmia, process for the preparation of said salt as well as the use of said |
| 5055490 |
Stereoisomers of benzonitrile derivatives, useful as cardiac arrhythmiac agents |
October 8, 1991 |
| 4-[3-[ethyl[3-((R*)-propylsulfinyl)propyl]amino]-2(R)-hydroxypropoxy]-benzo nitrile,4-[3-[ethyl[3-((S*)-propylsulfinyl)propyl]amino]-2(R)-hydroxypropoxy]-benzo nitrile,4-[3-[ethyl[3-((R*)-propylsulfinyl)propyl]amino]-2(S)-hydroxypropoxy]-benzo nitrile,4-[3-[ethyl[3-[((S*)-propylsulfinyl)pro |
| 5049674 |
Therapeutically active fluoro substituted benzimidazoles |
September 17, 1991 |
| The novel compounds of the formulas I and I' ##STR1## wherein F is in 5 or 6 position and ##STR2## wherein in both formulas R is the group --CH.sub.2 OCOOR.sup.1, wherein R.sup.1 is a straight or branched alkyl containing 1-6 carbon atoms or benzyl, or R.sup.1 is the group |
| 5039808 |
Therapeutically active cyclopropyl substituted compound |
August 13, 1991 |
| The novel compound 5-fluoro-2[[(4-cyclopropylmethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimid azole and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions containing the compound as active ingredient, and the use of the compound in medicine. |
| 5025024 |
Therapeutically active fluoro-substituted compound |
June 18, 1991 |
| The novel compound 4-fluoro-2-[[(4-methoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions containing such compounds as active ingredient, and the use of the compound in medicine. |
| 5019584 |
Therapeutically active chloro substituted benzimidazole |
May 28, 1991 |
| 5-Chloro-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and physiologically acceptable salts thereof as well as an intermediate, pharmaceutical compositions containing such compound as active ingredient, and the use of the compound in medicine. |
| 5008278 |
Therapeutically active compound and a process for its preparation |
April 16, 1991 |
| The novel compound 5-fluoro-2[[(4-cyclopropylmethoxy-2-pyridinyl) methyl]sulfinyl]-1H-benzimidazole and physiologically acceptable salts thereof as well as intermediates, pharmaceutical compositions containing the compound as active ingredient, and the use of the compound in medicine |
| 5001161 |
Pharmaceutical composition comprising metroprolol succinate |
March 19, 1991 |
| The present invention relates to metoprolol succinate, a new therapeutically active compound, and pharmaceutical preparations comprising this new compound. |
| 4957745 |
Pharmaceutical preparation |
September 18, 1990 |
| Controlled release preparation containing a number of beads comprising a salt of metoprolo as the main soluble component, a method for the production thereof and the use in the treatment of cardiovascular disorders. |
| 4942040 |
Pharmaceutical preparation and a process for its preparation |
July 17, 1990 |
| Preparation giving a controlled and extended release of both a dihydropyridine, e.g. felodipine and a .beta.-adrenoreceptor antagonist, namely metoprolol as well as a method for the manufacture of the new preparation. |
| 4927640 |
Controlled release beads having glass or silicon dioxide core |
May 22, 1990 |
| Controlled release preparation containing a number of insoluble beads applied with one or more pharmaceutically active compounds, a method for the production thereof and the use in a treatment where a controlled release of a pharmaceutically active compound is needed. |
| 4853230 |
Pharmaceutical formulations of acid labile substances for oral use |
August 1, 1989 |
| Pharmaceutical preparation containing an acid labile compound together with an alkaline reacting compound or an alkaline salt of an acid labile compound optionally together with an alkaline compound as the core material, one or more subcoating layers comprising inert reacting compoun |
| 4803081 |
New pharmaceutical preparations with extended release |
February 7, 1989 |
| An extended release perparation of an active compound with very low solubility containing the active compound dissolved or dispersed in a semi-solid or liquid non-ionic solubilizer and whereby the amount by weight of the solubilizer is at least equal to the amount by weight of the ac |
| 4777293 |
Method for the synthesis of pharmacologically active compounds and intermediates for such synthe |
October 11, 1988 |
| A process for the preparation of an aryloxypropanolamine of the formulawherein Ar is a carbocyclic or heterocyclic aromatic group and R is an alkyl or substituted alkyl group having 1 to 6 carbon atoms, characterized in subjecting a compound of the formula ##STR1## to oxidative cleav |
| 4772686 |
Enzyme inhibition |
September 20, 1988 |
| Peptides wherein an amide bond is replaced by nonhydrolyzable isosteric linkage are disclosed as thrombogenic inhibitors. |
| 4725691 |
2-[8-quinolinyl]-sulphinyl-1H-benzimidazole |
February 16, 1988 |
| Novel compounds of the formula IIIa ##STR1## wherein R.sup.1a, R.sup.2a, R.sup.3a and R.sup.4a are the same or different and are hydrogen, an alkyl, alkoxy optionally completely or predominantly substituted by fluorine or chlorine, halogen, --CN, --CF.sub.3, --NO.sub.2, --COR, -- |
| 4713445 |
Renin inhibitors and treatments using them |
December 15, 1987 |
| Renin-inhibiting analogues of formula ##STR1## where X and W are terminal groups optionally with further amino acyl residues; D, E, B and Z (of which any one or except with `reduced` analogues any two may be absent) are aromatic, lipophilic or in the case of E aromatic lipophilic |
| 4695272 |
Drug release device |
September 22, 1987 |
| A drug release device for inclusion in a parenteral drug delivery system, said device comprising a chamber having an inlet for a liquid administerable to a patient by a parenteral route, a drug dissolution space within said chamber, through which said liquid can be made flow, an outl |
| 4689331 |
Substituted 2-pyridinyl benzimidazoles, and their use for inhibiting gastric acid secretion |
August 25, 1987 |
| Novel compounds of the formula I ##STR1## and its salts; process for the preparation thereof, pharmaceutical compositions containing such compounds and their use in medicine to affect gastric acid secretion and provide gastrointestinal cytoprotection. |
| 4636501 |
Para-substituted 3-phenoxy-1-carbonylamino-alkylamino-propanol compounds, beta receptor blocking |
January 13, 1987 |
| Compounds of the formula ##STR1## having beta receptor blocking properties, are disclosed. |
| 4636499 |
Sulphenamides |
January 13, 1987 |
| Novel compounds of the formula IIIa ##STR1## wherein R.sup.1a, R.sup.2a, R.sup.3a and R.sup.4a are the same or different and are hydrogen, an alkyl, alkoxy optionally completely or predominantly substituted by fluorine or chlorine, halogen, --CN, --CF.sub.3, --NO.sub.2, --COR, -- |
| 4620008 |
Processes for the preparation of omeprazole and intermediates therefore |
October 28, 1986 |
| Novel compounds of the formula ##STR1## wherein R is H or CH.sub.3, a process for their preparation, and their use as intermediates in the preparation of pharmaceutically useful compounds, e.g. substituted benzimidazoles containing a pyridine radical, i.a. omeprazole. |
| 4544750 |
Certain pyridyl-N-oxide intermediates for the preparation of omeprazole |
October 1, 1985 |
| Novel compounds of the formula ##STR1## wherein R is H or CH.sub.3, a process for their preparation, and their use as intermediates in the preparation of pharmaceutically useful compounds, e.g. substituted benzimidazoles containing a pyridine radical, i.a. omeprazole. |
| 4508905 |
Substituted 2-(-benzimidazolyl)pyridines |
April 2, 1985 |
| The present invention relates to novel compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are each hydrogen, alkyl, halogen, carbomethoxy, carbethoxy, alkoxy, or alkanoyl, R.sup.6 is hydrogen, methyl or ethyl, R.sup.3, R.sup.4 and R.sup.5 are |
| 4465667 |
Process for the preparation of gastric acid neutralizing agents, gastric acid neutralizing agent |
August 14, 1984 |
| The present invention relates to gastric acid neutralizing compositions comprising dried aluminum hydroxide in suspension form, whereby the composition as suspension stabilizing and suspension forming agent comprises a hydrogenated, hydrolyzed glucose polymer in an amount of 2 to 30% |
| 4341759 |
Granule having controlled release properties |
July 27, 1982 |
| A method of preparing a preparation made up by bodies comprising an active component in decreasing concentration towards the surface of the bodies. The method comprises coating a particle with a composition comprising the active component in a continuous coating operation whereby the |
| 4337257 |
Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, their preparation, |
June 29, 1982 |
| The present invention relates to novel compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are each hydrogen, alkyl, halogen, carbomethoxy, carbethoxy, alkoxy, or alkanoyl, R.sup.6 is hydrogen, methyl or ethyl, R.sup.3, R.sup.4 and R.sup.5 are |
| 4336267 |
Heart active compounds and methods of use |
June 22, 1982 |
| This invention relates to novel compounds of the general formula ##STR1## Representative compounds within the scope of the invention are ##STR2## The compounds are disclosed as being useful for treating symptoms and signs of cardiac failure by stimulating the .beta.-receptors of |
| 4289795 |
Method for preparing preparations having controlled release of an active component |
September 15, 1981 |
| A method of preparing a preparation made up by bodies comprising an active component in decreasing concentration towards the surface of the bodies. The method comprises coating a particle with a composition comprising the active component in a continuous coating operation whereby the |
| 4264611 |
2,6-Dimethyl-4-2,3-disubstituted phenyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid-3,5-asymmetri |
April 28, 1981 |
| The present invention relates to new compounds having antihypertensive effect, which compounds are of the formula I, ##STR1## wherein R.sup.1 is selected from the group consisting of --CH.sub.3, --C.sub.2 H.sub.5, --CH.sub.2 CH.sub.2 OCH.sub.3, and --CH.sub.2 CH.sub.2 OC.sub.2 H. |
| 4263325 |
.beta.-Receptor blocking compounds and treatment of cardiovascular disorders therewith |
April 21, 1981 |
| Amines of the formula I ##STR1## method of preparing the same and pharmaceutical compositions and method for treating cardiovascular disorders by blocking the .beta.-receptors of the heart in combination with a peripheral vasodilating activity. |
| 4263323 |
.beta.-Receptor blocking compounds and treatment of cardiovascular disorders therewith |
April 21, 1981 |
| Amines of the formula I ##STR1## method of preparing the same and pharmaceutical compositions and method for treating cardiovascular disorders by blocking the .beta.-receptors of the heart in combination with a peripheral vasodilating activity. |
| 4261971 |
Pharmaceutically preparation comprising a cardiac glycoside in combination with a polymer |
April 14, 1981 |
| A solid pharmaceutical preparation for administration in dosage unit form comprising a therapeutically effective cardiac glycoside, whereby each dosage unit is to comprise a plurality of bodies, each of said bodies having a pharmaceutically inert core and a layer thereon containing the |
| 4255431 |
Gastric acid secretion inhibiting substituted 2-(2-benzimidazolyl)-pyridines, pharmaceutical pre |
March 10, 1981 |
| The present invention relates to novel compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are each hydrogen, alkyl, halogen, carbomethoxy, carbethoxy, alkoxy, or alkanoyl, R.sup.6 is hydrogen, methyl or ethyl, R.sup.3, R.sup.4 and R.sup.5 are |
| 4244969 |
Heart active compounds |
January 13, 1981 |
| This invention relates to novel compounds of the general formula ##STR1## Representative compounds within the scope of the invention are ##STR2## The compounds are disclosed as being useful for treating symptoms and signs of cardiac failure by stimulating the .beta.-receptors of |
| 4191744 |
Neutralizing agent |
March 4, 1980 |
| A gastric acid neutralizing agent in the form of a clear aqueous solution of a watersoluble, non-crosslinked polyethyleneimine, a taste improving acid selected from the group of alginic acid, polygalacturonic acid, galacturonic acid, pectin, tannic acid, arabic acid, galactaric acid and |
| 4165384 |
Amide substituted phenoxy propanol amines |
August 21, 1979 |
| An amine of the formula I set forth below ##STR1## and a method for the preparation thereof and treating cardiovascular diseases to exert its .alpha.-receptor blocking activity. |
