| Patent Number |
Title Of Patent |
Date Issued |
| 5728863 |
Process for producing .alpha.-L-aspartyl-L-phenylalanine methyl ester |
March 17, 1998 |
| Wet crystals of .alpha.-L-aspartyl-L-phenylalanine methyl ester with low water content can be obtained with high efficiency by solid-liquid separation of an aqueous suspension of .alpha.-L-aspartyl-L-phenylalanine methyl ester. The aqueous suspension is compressed at a final pressure of |
| 5705370 |
Process for producing L-amino acids by fermentation |
January 6, 1998 |
| Culturing an L-amino acid producing microorganism belonging to the genus Brevibacterium or Corynebacterium and having a resistance to a peptide containing glutamic acid or aspartic acid gives L-amino acids in high yield. |
| 5540924 |
Composition for the prevention and treatment of white diarrhea and diarrhea in livestock, etc. |
July 30, 1996 |
| A composition for the prevention and treatment of diarrhea in animals, containing sterilized cells of bacteria belonging to the genus Bacillus, Brevibacterium, Corynebacterium, Escherichia, Lactobacillus, Streptococcus, or Streptomyces, a cell homogenate of said sterilized cells, a c |
| 5473097 |
Granules of .alpha.-L-aspartyl-L-phenylalanine methyl ester |
December 5, 1995 |
| Granules of .alpha.-L-aspartyl-L-phenylalanine methyl ester, containing IB crystals of the ester and having a grain size of from 100 to 1400 .mu.m have improved water solubility. |
| 5372810 |
Composition for the prevention and treatment of diarrhea in livestock |
December 13, 1994 |
| A composition and method for the prevention and treatment of diarrhea in domesticated animals, comprising sterilized cells of aerobic bacteria belonging to the genus Bacillus, Brevibacterium, Corynebacterium, Escherichia, Lactobacillus, Streptococcus, or Streptomyces, a cell homogena |
| 5294547 |
Process for producing L-amino acids by fermentation employing a microorganism with resistance to |
March 15, 1994 |
| Culturing an L-amino acid producing microorganism belonging to the genus Brevibacterium or corynebacterium and having a resistance to a dipeptide containing glutamic acid or aspartic acid gives L-amino acids in high yield. |
| 5292757 |
1,4-dihydropyridine compounds useful as reverse resistance agents |
March 8, 1994 |
| 1,4-dihydropyridine derivatives of Formula 1 or pharmaceutically acceptable salts thereof: ##STR1## wherein the substituents are disclosed herein and which are useful against tumor cells which have acquired resistance to one or more drugs used as chemotherapeutic agents. |
| 5284757 |
Process for producing l-arginine by fermentation with brevibacterium or corynebacterium |
February 8, 1994 |
| L-arginine is produced in high yields by culturing a microorganism of the genus Brevibacterium or the genus Cornyebacterium, which is resistant to a compound of the formula X-guanidine, wherein X is an aliphatic group or derivative thereof. The preferred microorganisms are Brevibacterium |
| 5244661 |
Process for producing a polyene antibiotic |
September 14, 1993 |
| By irradiating a polyene antibiotic having a cis-type polyene structure with long wavelength ultraviolet light, it is possible to prepare the corresponding antibiotic having a trans-type polyene structure in high yield in a simple manner. Such antibiotics having a trans-type polyene |
| 5206160 |
Composition containing buf-3 and superoxide dismutase as a cell cleavage promoting agent |
April 27, 1993 |
| A cleavage promoting agent comprising as an effective ingredient at least one of the polypeptides BUF-3, BUF-4 and BUF-5 is useful for the treatment of fertilized or unfertilized ova in order to promote cell division and improve reproduction efficiency. |
| 5200395 |
Pharmaceutical composition of BUF-5 for treating anemia |
April 6, 1993 |
| The polypeptides BUF-4 and BUF-5 may be used to treat osteoporosis, cancer, and anemia, and pharmaceutical compositions containing BUF-4 and/or BUF-5 are disclosed. |
| 5185327 |
Glucan derivatives having tumoricidal activity |
February 9, 1993 |
| A new glucan derivative having at least one side chain branch of a compound selected from the group consisting of galactopyranose, L-arabinofuranose and oligomers thereof is disclosed. These glucan derivatives have high tumoricidal activity and are usable as a tumoricide. |
| 5116631 |
Low-calorie food products containing konjak mannan and processes for preparing the same |
May 26, 1992 |
| Low-calorie foods containing konjak mannan, such as meringues and mayonnaise-like foods, and processes for preparing such foods are disclosed. |
| 5074959 |
Complex of fibers and fungi and a process for preparation thereof |
December 24, 1991 |
| A complex of fibrous material and fungi is prepared by allowing fungi to grow in a medium containing a fibrous material. |
| 5070208 |
Method for crystallization of optically active tryptophan |
December 3, 1991 |
| Optically active tryptophan is crystallized by a modification of a method of crystrallization of optically active tryptophan through neutralization by mixing an acidic or alkaline aqueous solution of optically active tryptophan, which is obtained by the removal of impurities from an acid |
| 5028622 |
Administration of amino acids as treatment for neurodegenerative disorders |
July 2, 1991 |
| A treatment and composition for preventing in mammals the progressive exacerbation of symptoms associated with neurodegenerative disorders characterized by abnormal glutamate metabolism, elevated levels of peripheral glutamate or altered glutamate receptor characteristics. The treatm |
| 4988013 |
Container lid structure and method for manufacturing the same |
January 29, 1991 |
| A container lid structure made essentially of plastics. The lid structure includes a lid frame and a lid plate. The lid plate includes an inner layer comprising a metal foil coated at the opposite sides by plastic layers and connected at the peripheral portion with the lid frame and a |
| 4974458 |
Automatic preparation apparatus and support arm |
December 4, 1990 |
| An automatic preparation apparatus has turntable means in which a plurality of test tubes can be disposed in radial direction, filter robot means which can move a releasable filter onto one of those test tubes, and probe robot means which can sample the liquid contained within one of the |
| 4973581 |
Glucan derivatives having tumoricidal activity |
November 27, 1990 |
| A new glucan derivative having at least one side chain branch of a compound selected from the group consisting of galactopyranose, L-arabinofuranose and oligomers thereof is disclosed. These glucan derivatives have high tumoricidal activity and are usuable as a tumoricide. |
| 4956471 |
Process for isolating and purifying amino acids |
September 11, 1990 |
| A process for isolating and purifying an amino acid, which comprises subjecting an aqueous solution of said amino acid containing impurities composed mainly of at least one member selected from the group consisting of acidic amino acids, lysine, ornithine, citrulline, histidine, PCA, |
| 4951513 |
Automatic preparation apparatus and filter therefor |
August 28, 1990 |
| An automatic preparation apparatus has turntable means in which a plurality of test tubes can be disposed in radial direction, filter robot means which can move a releasable filter onto one of those test tubes, and probe robot means which can sample the liquid contained within one of the |
| 4912134 |
Azulene derivatives and pharmaceutical compositions containing them |
March 27, 1990 |
| Azulene derivatives of the following formula ##STR1## wherein R.sup.1 stands for an alkyl group of 1 to 3 carbon atoms, R.sup.2 stands for an alkyl group of 1 to 3 carbon atoms, and R.sup.3 is at the 5- or 6-position and stands for an alkyl group of 1 to 6 carbon atoms, an aryl g |
| 4877583 |
Fluorescent analyzer |
October 31, 1989 |
| A fluorescent analyzer including a light source which irradiates a sample with direct light, a first wave selector for passing a predetermined wavelength of light emitted from the light source, a sample cell for holding the sample which is irradiated by light passed by the first wave |
| 4861722 |
Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production o |
August 29, 1989 |
| A genetic sequence coding for the production of a protein having the activity of diaminopimelic acid decarboxylase and having two Pst I cleavage sites in its DNA chain and a molecular weight of 2.9.+-.0.05 Md, is incorporated into a vehicle capable of replication in Coryneform bacter |
| 4592858 |
Smectic liquid crystal compound and liquid crystal compositions |
June 3, 1986 |
| A liquid crystal compound of the formula: ##STR1## wherein R.sup.1 is an alkyl group, X is chloro or bromo, and R.sup.2 is a branched-alkyl group; and the carbon atom marked with an * is an asymmetric carbon atom. |
| 4451399 |
Imidazolecarboxylic acid derivatives |
May 29, 1984 |
| The invention relates to imidazolecarboxylic acid derivatives of penicillins and cephalosporins, which are especially useful for the treatment of Pseudomonas aeruginosa-derived infections in humans and other animals. |
| 4423215 |
Method of preparing sodium salts of imidazoledicarboxylic acid substituted cephalosporin derivat |
December 27, 1983 |
| A method of preparing sodium salts of an imidazoledicarboxylic acid derivative of a substituted cephalosporin represented by the general formula of ##STR1## where X is a radical selected from the group consisting of hydrogen, halogen, hydroxyl, alkyl, aryl, aralkyl, alkoxy, arylo |
| 4399162 |
Dipeptide sweetening composition |
August 16, 1983 |
| A dipeptide sweetening composition, comprising a unit weight of a dipeptide sweetener and at least one flavoring agent in an amount sufficient to impart the tasting strength equal to that of 10 to 200% by weight of monosodium L-glutamate based upon the weight of the dipeptide sweetener, |
| 4350763 |
Method for determining biochemical oxygen demand |
September 21, 1982 |
| The biochemical oxygen demand (BOD) of an aqueous liquid contaminated with organic matter is determined by contacting a sample solution with elementary oxygen and with immobilized microorganisms capable of aerobically metabolizing the organic matter and of thereby consuming the oxyge |
| 4332718 |
Process for producing an .alpha.-L-aspartyl-L-phenylalanine lower alkyl ester |
June 1, 1982 |
| A process for producing an .alpha.-L-aspartyl-L-phenylalanine lower alkyl ester or its hydrochloride which comprises (a) treating an L-N-(1-methyl-2-lower aliphatic acylvinyl or 1-methyl-2-lower alkoxycarbonylvinyl)-aspartic acid or an alkali metal salt thereof with a dehydrating age |
