| Patent Number |
Title Of Patent |
Date Issued |
| 6562808 |
5,11-dihydrodibenzo[b,e][1,4]oxazepine derivatives and pharmaceutical composition containing the |
May 13, 2003 |
| 5,11-dihydrodibenzo[b,e][1,4]oxazepine derivatives of the following general formulae and analogs thereof have a calcium channel-antagonistic effect and they are effective in treating and preventing intestinal diseases such as abnormal motor function of digestive tracts, particularly, irr |
| 6561203 |
Container cleaning, draining and drying apparatus |
May 13, 2003 |
| Herein is disclosed a container cleaning, draining and drying apparatus comprising: a transfer mechanism for transferring a container filled with a content; a cleaning mechanism for cleaning an outer surface of the container during the transfer; a draining mechanism for draining the |
| 6555708 |
N-.epsilon.-long chain acyllsine crystals, process for producing the same and cosmetics containi |
April 29, 2003 |
| There are provided cosmetics which have not only a reduced effect on the "gleam" caused by irregular light reflection but also a reduced effect on "stickiness" based on an oil raw material, giving a good feeling during use such as spreadability, etc., and being excellent in the sustainin |
| 6555584 |
Acylsulfonamide derivative |
April 29, 2003 |
| This invention provides a novel acylsulfonamide derivative which can be used as an ACC activity inhibitor effective for the treatment of visceral fat syndrome that becomes the risk-factor of diseases of adult people such as myocardial infarction, cerebral infarction and diabetes.Particul |
| 6552061 |
Amino acid derivatives and anti-inflammatory agents |
April 22, 2003 |
| Provided are an anti-inflammatory agent containing, as an active ingredient, at least one selected from amino acid derivatives represented by formula (I) ##STR1##wherein Ar represents an optionally substituted 2-hydroxyaryl group, n is 0 or 1, R.sup.2 represents a hydrogen atom or a |
| 6548096 |
Aspartyl dipeptide ester derivatives and sweeteners |
April 15, 2003 |
| Low-calory sweeteners comprising novel aspartyl dipeptide ester derivatives and their salts have a sweetening potency of up to 35000 times that of sugar and include compounds such as N-[N-[3-(3-methyl-4-hydroxyphenyl)propyl]-L-.alpha.-aspartyl]-L-phenylalan ine 1-methyl ester and |
| 6545166 |
Process for producing spiro acetal derivative |
April 8, 2003 |
| In this application is disclosed a process for producing 3,9-bis(2-chloroethyl)-2,4,8,10-tetraoxaspiro[5.5]undecane comprising a step of reacting acrolein, pentaerythritol, and hydrogen chloride at one step, according to which the compound can be obtained conveniently in high yields. |
| 6538160 |
Process for producing .alpha.-aminohalomethyl ketone derivatives |
March 25, 2003 |
| Herein is disclosed a process for producing an .alpha.-aminohalomethyl ketone derivative which comprises subjecting to catalytic reduction the corresponding .alpha.-aminodihalomethyl ketone derivative, and which process is efficient and suited for industrial production thereof. |
| 6538133 |
Process for producing xylitol of high purity |
March 25, 2003 |
| Herein are disclosed a process for producing xylitol of high purity (one-step desalting process) which comprises the steps of (1) removing the solid matter from a culture froth obtained by culturing a xylitol-producing microorganism in an aqueous culture medium, (2) desalting the res |
| 6538122 |
Process for producing microbial transglutaminase |
March 25, 2003 |
| Disclosed are a protein having a transglutaminase activity, which comprises a sequence ranging from serine residue at the second position to proline residue at the 331st position in an amino acid sequence represented by SEQ ID No. 1 wherein the N-terminal amino acid of the protein corres |
| 6534305 |
Process for aerobic culture using sintered metal membrane |
March 18, 2003 |
| A process for aerobic culture in which ammonia and oxygen are simultaneously supplied, comprising: dispersing and supplying air, oxygen, or a mixed gas thereof into a culture tank through a sintered metal membrane attached the end of a diffusing pipe, and simultaneously, dispersing a |
| 6528504 |
Oxazepine derivatives and medicine containing the same |
March 4, 2003 |
| The present invention provides (R)-5,11-dihydro-5-[1-(4-methoxyphenethyl)piperidine-2-ylmethyl]dibenzo[b, e][1,4]oxazepine, (R)-5,11-dihydro-5-[1-(4-dimethylaminophenethyl)piperidine-2-ylmethyl]dibe nzo[b,e][1,4]oxazepine, compounds analogous to them and pharmaceutical compositions |
| 6528068 |
Cosmetic composition containing N-acyl neutral amino acid esters of lower alcohols |
March 4, 2003 |
| An N-long-chain acyl neutral amino acid ester containing a straight-chain or branched-chain, saturated or unsaturated acyl group having from 6 to 22 carbon atoms, where the hydrocarbon group of the alcohol constituting the ester is a straight-chain or branched-chain, saturated or unsatur |
| 6506431 |
Spore germination inhibitor and food containing the same |
January 14, 2003 |
| The spore germination inhibitor of the invention is 6-carbamoyl-2-pyridine carboxylic acid which is produced by a microorganism of genus Bacillus, such as Bacillus subtilis, and can inhibit germination of sporogenous bacteria resulting in the prevention of spoilage and putrefaction of |
| 6503550 |
Method for controlling the temperature of edible dough during kneading step |
January 7, 2003 |
| A method for controlling the temperature of edible dough to efficiently and promptly control the dough temperature without adversely affecting the working environments, to operate them for a long period of time, and to apply them to any type of a mixer. The method for controlling the |
| 6500985 |
Process for producing alpha-aminoketones |
December 31, 2002 |
| An amino group of an .alpha.-amino acid ester is protected as an imine, and it is then reacted with a halomethyllithium to obtain an N-protected-.alpha.-aminohalomethylketone. Further, this N-protected-.alpha.-aminohalomethylketone is treated with an acid to obtain an .alpha.-aminoha |
| 6500946 |
Methods for producing nucleoside derivatives and intermediates therefor |
December 31, 2002 |
| Novel intermediates of nucleoside derivatives, of which the 6-position of the nucleic acid base moiety is substituted with a halogen atom, are produced. Using those novel intermediates, even substrates, of which the 3'-position of the saccharide moiety is deoxylated, can be substituted a |
| 6500889 |
Flame-retarded thermoplastic resin composition |
December 31, 2002 |
| Herein is disclosed a flame-retarded thermoplastic resin composition which comprises an original flame-retarded thermoplastic resin composition comprising certain amounts of a thermoplastic resin and of a brominated flame-retardant, and, in combination therewith, a certain amount of a |
| 6491957 |
Chinese snacks |
December 10, 2002 |
| Chinese snacks having a proteinic adhesive layer with which transglutaminase has reacted, formed between the filling and the dumpling skin thereof are disclosed, and uncooked Chinese snacks half-made in such that a proteinic adhesive layer can be formed between the filling and the du |
| 6482978 |
Production method of aromatic carboxylic acid derivative |
November 19, 2002 |
| The present invention provides methods for producing a highly pure aromatic bromocarboxylic acid derivative and an aromatic acylthiocarboxylic acid derivative in high yields. The methods of the present invention include reacting an aromatic amino acid in an aqueous solvent in the presenc |
| 6482899 |
Curable resin composition |
November 19, 2002 |
| A latent curing agent is disclosed for epoxy resin, comprising a reaction product obtainable by allowing (A) an epoxy compound having more than one epoxy groups on the average in the molecule and (B) a compound having in the molecule both a tertiary amino group and at least one functiona |
| 6476049 |
Therapeutic agent for intermittent claudication |
November 5, 2002 |
| A compound 1-formyl-N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-piperidinyl)) ethyl isonipecotic acid amide or an analog thereof or a pharmaceutically acceptable salt thereof provides a therapeutic agent for treating a patient suffering from intermittent claudication. |
| 6475956 |
Flower-opening promoting agent for plants |
November 5, 2002 |
| Herein is disclosed an excellent flower-opening promoting agent for plants which agent comprises inosine as the effective ingredient, and a method of promoting the opening of flowers with the promoting agent. |
| 6475542 |
Edible microcapsule and food containing the same |
November 5, 2002 |
| An edible microcapsule comprising a core and a capsule wall, wherein the core is an edible hydrophobic substance, the capsule wall is formed by salting-out of a combination of a protein and an edible salt, and transglutaminase is used as a crosslinking agent for hardening (solidifyin |
| 6472182 |
Process for producing transglutaminase by microorganism |
October 29, 2002 |
| The present invention provides a process for producing a transglutaminase, which comprises culturing microorganisms of any of the genus Micrococcus, Clostridium, Torulopsis, Rhizopus and Monascus in a medium to produce the intended transglutaminase in the medium or in the cells of the |
| 6465243 |
Culture device for aerobic culture and method of controlling foams by defoaming |
October 15, 2002 |
| A foam detecting sensor (7) and an ultrasonic oscillation horn (13) are mounted on a vertical pipeline between a culture tank (1) and a liquid-vapor separating device (5). When overflowed foams are subjected to ultrasonic irradiation, they burst and lose volume. The burst foams have |
| 6462087 |
Anti-tumor composition |
October 8, 2002 |
| The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and |
| 6461852 |
Dihydrodipicolinate synthase from Bacillus methanolicus |
October 8, 2002 |
| The present invention provides dihydropicolinate synthase and dihydrodipicolinate reductase enzymes from Bacillus methanolicus, polynucleotides encoding the enzymes, and methods of producing L-lysinse in microorganisms expressing the enzymes. |
| 6455273 |
Method for producing a protein hydrolysate with low bitterness |
September 24, 2002 |
| A method for producing a protein hydrolysate with low bitterness by contacting a protein with a protease having a low specificity to cleave a site of a hydrophobic amino acid residue in the protein. |
| 6448202 |
Withering-preventing and quick-acting nutrition supplementing agent for gramineous plants |
September 10, 2002 |
| Herein is disclosed a withering-preventing and quick-acting nutrition supplementing agent for a gramineous or the like plant such as a lawn grass or the like which agent comprises, as the effective ingredient (s), proline alone or both proline and inosine concurrently, according to which |
| 6447824 |
Substitute for edible oil and fat |
September 10, 2002 |
| A substitute for edible oil and fat, which contains fine particles having an average particle size of 250 microns or less and a surface hydrophobic degree of 35 g or less as the oil absorption measured by the oil absorption assay method of JIS K6223, as well as a food containing the |
| 6447790 |
Oily material composition |
September 10, 2002 |
| Herein is disclosed an oily material composition comprising, as effective components, both a specific alkyl or alkenyl ester of an N-long chain acyl neutral amino acid and a specific sterol ester of an N-long chain acyl neutral amino acid, or further an amphipathic substance in addition |
| 6444821 |
Crystals of piperidine derivatives, intermediates for production of the same, and process for pr |
September 3, 2002 |
| Monohydrate and trihydrate crystals of N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidino) ethyl)-1-formyl-4-piperidinecarboxamide hydrochloride having excellent stability. |
| 6444800 |
Human gastric cancer antigen gene and gastric cancer antigen protein |
September 3, 2002 |
| A tumor antigen gene is identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen specific cytotoxic T cell (CTL) by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric cancer a |
| 6444251 |
Sweetener compositions containing aspartame and aspartame derivative |
September 3, 2002 |
| A homogeneous sweetener composition containing aspartame (APM) and N-[N-(3,3-dimethylbutyl)-L-.alpha.-aspartyl]-L-phenylalanine methyl ester having tasting properties similar to sucrose, can be efficiently produced in high yields and with a high purity by reductive alkylation of APM with |
| 6436922 |
5,11-dihydrobenzo[b,e][1,4]oxazepine derivatives and pharmaceutical compositions containing the |
August 20, 2002 |
| Disclosed are 5,11-Dihydrodibenzo[b,e][1,4]oxazepine derivatives such as (R)-(+)-5,11-dihydro-5-[1-(4-methoxyphenethyl)-2-pyrrolidinylmethyl]dibenz o[b,e][1,4]oxazepine and (R)-(+)-5,11-dihydro-5-[1-(4-fluorophenethyl)-2-pyrrolidinylmethyl]dibenzo [b,e][1,4]oxazepine, stereoisomers the |
| 6436664 |
Method for producing shikimic acid |
August 20, 2002 |
| A method for producing shikimic acid, comprising the steps of cultivating a bacterium belonging to the genus Bacillus which is deficient in shikimate kinase activity and has shikimic acid productivity, or a bacterium belonging to the genus Bacillus which is deficient in 5-enolpyruvyl |
| 6433123 |
Curable resin composition for overcoat of flexible circuit |
August 13, 2002 |
| Herein are disclosed a curable resin composition for overcoat of flexible circuit which comprises a hydrogenated polybutadiene polyol with a number-average molecular weight of 1,000-8,000 and having 2-10 hydroxyl groups per molecule (Polyol A), and a polybutadiene polyblock isocyanate |
| 6432458 |
Enzyme preparations and process for producing noodles |
August 13, 2002 |
| A process for producing noodles, which includes using (1) a transglutaminase and (2) a carbonate and/or a reducing agent, and optionally, a protein partial hydrolyzate, in addition to starting materials such as cereal flour as the main starting material, whereby noodles of which the |
| 6426469 |
Printed board with signal wiring patterns that can measure characteristic impedance |
July 30, 2002 |
| A plain layer in a forming area of a measuring wiring pattern is patterned so that its copper-containing amount may be coincided with a copper-containing amount in a forming area of a measurement target signal wiring pattern. Thereby, it is possible to coincide a thickness of an insu |
| 6423335 |
Modified milk powder composition |
July 23, 2002 |
| A composition comprising modified milk powder, and glutamine and/or a peptide containing glutamine. |
| 6423182 |
Surface-sizing agent and recording paper comprising same |
July 23, 2002 |
| A surface-sizing agent for providing a recording paper contains bacterial cellulose and/or plant-originated fine fibrous cellulose (having an average diameter of 10 .mu.m or less), and a cationic polymer. The cationic polymer may be at least partially bonded to the bacterial cellulos |
| 6410538 |
Benzamidine derivatives |
June 25, 2002 |
| Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases c |
| 6403221 |
Epoxy resin composition, and adhesive film and prepreg using the composition, and multilayer pri |
June 11, 2002 |
| Epoxy resin compositions which comprise, as essential components, (A) an epoxy resin having two or more epoxy groups in one molecule, (B) a phenolic curing agent, (C) a phenoxy resin containing a bisphenol S skeleton and having a weight average molecular weight of 5,000 to 100,000, a |
| 6403127 |
Method for producing noodles |
June 11, 2002 |
| A method for producing elastic and glutinous noodles is provided that includes adding transglutaminase and either gliadin or glutenin to cereal. The noodles keep their original elasticity and glutinosity for a long period of time, even after having been boiled and acid-processed or r |
| 6395528 |
Phosphoserine phosphatase gene of coryneform bacteria |
May 28, 2002 |
| The present invention provides a DNA coding for a protein defined in the following (A) or (B) is obtained from Brevibacterium flavum chromosomal DNA library by cloning a DNA fragment that complicates serB deficiency of Escherichia coli as a open reading frame in the DNA fragment.(A) A pr |
| 6395322 |
Method for producing frozen fried foods for microwave cooking |
May 28, 2002 |
| There is provided a method for producing a frozen fried food for a microwave cooking comprising the step of a freezing of, particularly a very quick freezing (immediate quick freezing) of a deep-fat fried food, more particularly immediately after the oil-cooking thereof, at a moving |
| 6391576 |
Method for isolating a microbe |
May 21, 2002 |
| The present invention provides a method for isolating a microbe whereby a sample of microbe cells is encapsulated in agarose gel particulates, wherein some of the particulates contain a single cell, and the other particulates contain more than one cell; incubating the particulates in |
| 6391350 |
Method for the pre-baking treatment of chunk of frozen bread dough |
May 21, 2002 |
| A method for pre-baking treatment of a chunk of frozen bread dough includes placing the chunk of frozen bread dough in a container and keeping an inner temperature of the container in a range of 17.degree. C. to 40.degree. C. and relative humidity in the container in a range of 50% to |
| 6387359 |
Nonionic surfactant |
May 14, 2002 |
| Herein are disclosed N-long chain acyl-neutral amino acid polyglycerin esters composed of a polyglycerin having a degree of glycerin polymerization of not smaller than 4 and an N-long chain acyl-neutral amino acid having an acyl group with from 6 to 22 carbon atoms and a nonionic sur |