| Patent Number |
Title Of Patent |
Date Issued |
| 6855716 |
Dihydropyrimidine compounds and compositions containing the same |
February 15, 2005 |
| Dihydropyrimidine derivatives of the following formula or analogs thereof have selective N-type calcium channel antagonistic activity, and they are used as therapeutic agents for various diseases participating in the N-type calcium channels. ##STR1## |
| 6855706 |
Phenylalanine derivatives |
February 15, 2005 |
| Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to .alpha. 4 integrin. They are used as therapeutic agents for various diseases concerning .alpha. 4 integrin. |
| 6852516 |
Method for producing L-glutamic acid by fermentation |
February 8, 2005 |
| A coryneform bacterium which has enhanced intracellular pyruvate carboxylase activity obtained by increasing copy number of a gene encoding the intracellular pyruvate carboxylase, or by enhancing function of a expression regulatory sequence for the gene, and has L-glutamic acid-produ |
| 6844465 |
Method for preparing highly stable crystals of aspartame derivative |
January 18, 2005 |
| Disclosed in the present application are a method for preparing highly-stable A-type crystals by controlling and maintaining the product temperature of B-type N-(3,3-dimethylbutyl)-APM crystals at 25 to 80.degree. C. under an absolute humidity of 0.203 kg/kg or less environment, ther |
| 6844008 |
Tablet composition |
January 18, 2005 |
| A tablet composition containing N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine and a disintegrant, selected from a low substituted hydroxypropylcellulose, sodium carboxymethyl cellulose, calcium carboxymethyl cellulose and sodium croscaramellose sodium, is disclosed. This t |
| 6841365 |
L-arginine producing Escherichia coli and method of producing L-arginine |
January 11, 2005 |
| Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate arginine in the medium, and collecting arginine from the medium. |
| 6841183 |
Process for producing aspartame derivatives, process for purifying aspartame derivatives, produc |
January 11, 2005 |
| N-[N-[3-(2-hydroxy-substituted phenyl)propyl]-L-.alpha.-aspartyl]-L-phenylalanine 1-methyl ester derivatives, which are useful as sweeteners, may be conveniently produced by subjecting a 2-hydroxychroman derivative having various substituents on the benzene ring and aspartame to a re |
| 6835407 |
Oil-in-water type emulsion food |
December 28, 2004 |
| There is provided an oil-in-water type emulsion food comprising a gelatin, in which the gelatin contains 13% by weight or less of a gelatin fraction having a molecular weight of 20,000 or less. The emulsion food exhibits a marked improvement in cold resistance such as refrigeration resis |
| 6833258 |
Process for producing transglutaminase |
December 21, 2004 |
| The present invention relates to a high-yield process for producing high-activity, high-purity transglutaminase by refolding denatured microorganism-derived transglutaminase by reacting denatured transglutaminase in an aqueous medium under acidic conditions and reconstituting a highe |
| 6830905 |
Glutaminase, its gene and a method of producing it |
December 14, 2004 |
| Glutaminase is purified from an Aspergillus oryzae, its partial amino acid sequence is determined, a partial sequence of glutaminase gene is obtained by PCR based on the obtained information, and DNA fragments containing glutaminase gene from Aspergillus oryzae genomic library and cDNA l |
| 6830759 |
Antidiabetic preparation for oral administration |
December 14, 2004 |
| There is provided a single preparation which directly decreases both of the post prandial blood glucose level and the fasting blood glucose level close to normal levels, by release-sustaining a drug capable of decreasing the post prandial blood glucose level of diabetic patients close to |
| 6825191 |
Benzodiazepine derivatives |
November 30, 2004 |
| The present invention provides benzodiazepine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of inhibiting activated blood-coagulation factor X. These compounds are u |
| 6825181 |
Aminoisoquinoline derivatives |
November 30, 2004 |
| Aminoisoquinoline derivatives of the following formulae or analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an excellent effect of inhibiting activated blood-coagulation factor X, and they are useful as anticoagulants or agents for prev |
| 6822111 |
Process for production of aspartyl dipeptide ester derivatives |
November 23, 2004 |
| N-[N-[3-(phenyl having various substituent group(s) on the benzene ring)propyl]-L-.alpha.-aspartyl]-L-phenylalanine 1-methyl ester derivatives, which are useful as sweeteners, may be conveniently produced on an industrial scale at a high yield by reductively alkylating aspartame with |
| 6821763 |
Process for producing microbial transglutaminase |
November 23, 2004 |
| Disclosed are a protein having a transglutaminase activity, which comprises a sequence ranging from serine residue at the second position to proline residue at the 331st position in an amino acid sequence represented by SEQ ID No. 1 wherein the N-terminal amino acid of the protein corres |
| 6821306 |
Method for producing mixed crystals of disodium 5'-guanylate and disodium 5'-inosinate |
November 23, 2004 |
| Herein is disclosed a method for producing mixed crystals of disodium 5'-guanylate and disodium 5'-inosinate which comprises feeding a mixed solution of disodium 5'-guanylate and disodium 5'-inosinate which solution will become supersaturated at the below-mentioned constant temperature, |
| 6818702 |
Thermosetting resin composition and flexible circuit overcoating material comprising the same |
November 16, 2004 |
| A thermosetting resin composition that is useful as an epoxy resin-based overcoating agent for flexible circuit boards or for film carriers for the TAB method, and the like, providing basic properties required of general insulation protective films, since the cured coated films are excel |
| 6818434 |
Cellulose-producing bacteria |
November 16, 2004 |
| Novel cellulose-producing bacteria including one capable of producing of a bacterial cellulose having a weight-average degree of polymerization in terms of polystyrene of 1.6.times.10.sup.4 or above, one capable of producing a bacterial cellulose containing a small amount of the fraction |
| 6818243 |
Crystals of aspartame derivative |
November 16, 2004 |
| N-[N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-L-.alpha.-aspartyl]-L-phenylalan ine 1-methyl ester useful as a sweetener with a high potency of sweetness, is provided in the crystalline form having a high stability and a good purity which is favorable as a commercial product. |
| 6818242 |
Production method of Chinese fried meat dumplings |
November 16, 2004 |
| A production method of Chinese fried meat dumplings includes loading meat dumplings on a conveyer, steaming the meat dumplings on the conveyer, and frying the meat dumplings by increasing a temperature of the conveyer from 50.degree. C. to 200-280.degree. C. in 1-8 minutes as the conveye |
| 6818241 |
Method for preparing cooked rice |
November 16, 2004 |
| The invention relates to a method of preparing cooked rice, comprising steaming raw rice having a water content of less than 30% by weight and then boiling the steamed rice, to cooked rice prepared according to the present method, and to cooked rice types comprising the cooked rice. |
| 6815428 |
Pyrazole derivatives and diabetic medicine containing them |
November 9, 2004 |
| The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine. ##STR1## |
| 6815195 |
5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optic |
November 9, 2004 |
| The present invention relates to a 5-substituted hydantoin racemase, which efficiently catalyzes racemization reactions at a high optimum temperature for racemization reactions, DNA coding for the racemase, and processes for producing optically active amino acids. |
| 6814998 |
Soybean embryo fat/oil and process for producing soybean material with high embryo concentration |
November 9, 2004 |
| The purpose of the present invention is to extract oil from the soybean material containing soybean germ as a main component, and to utilize it.The present invention relates to a method for producing a soybean material, comprising crudely crushing selected soybeans into a size of less than |
| 6814993 |
Method for producing just fresh-cooked food products and production system therefor |
November 9, 2004 |
| A system and method for planning all of the operations in a kitchen on the basis of estimated sale data and actual sale outcome data (sale situation). The system and method provides workers with detailed instructions about each cooking operation, such as its starting and finishing ti |
| 6812252 |
Acylsulfonamide derivatives |
November 2, 2004 |
| The present invention provides new acylsulfonamide derivatives such as 4-(3-trifluoromethyl)phenylethynyl-N-(2-(5-ketohexanoylamino)sulfonylpheny l)benzamide, 4-(3-trifluoromethyl)phenylethynyl-N-(2-(2-propyloxyacetylamino)sulfonylph enyl)benzamide or analogues thereof. These acylsulfo |
| 6812231 |
Benzamidine derivative |
November 2, 2004 |
| Benzamidine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof are provided. These compounds have an effect of inhibiting activated blood-coagulation factor X, and they are useful as agents for preventing or treating various diseases c |
| 6806384 |
Production method of .beta.-amino-.alpha.-hydroxycarboxylic acid |
October 19, 2004 |
| The present invention provides a production method of an optically active .beta.-amino-.alpha.-hydroxycarboxylic acid, which includes the following steps (a)-(c): (a) treating an optically active N-carbamate protected .beta.-amino epoxide with an acid to give an optically active 5-hyd |
| 6806049 |
Method for analyzing gene expression frequency |
October 19, 2004 |
| In gene expression frequency analysis, a vector primer to which each cDNA is ligated is formed by synthesizing the cDNA from each mRNA using by a vector primer having a poly(T) sequence; each cDNA sequence is converted to a tag on the vector primer; a concatemer is formed by ligating the |
| 6805958 |
Epoxy resin composition, and adhesive film and prepreg using the composition, and multilayer pri |
October 19, 2004 |
| The present invention provides an epoxy resin composition containing (A) an epoxy resin having two or more epoxy groups in one molecule, (B) a phenolic curing agent, (C) a phenoxy resin containing a bisphenol S skeleton and having a weight average molecular weight of 5,000 to 100,000, |
| 6803062 |
Process for producing hydrolyzed protein |
October 12, 2004 |
| A hydrolyzed protein which can be used as seasonings or the like is produced by heating and maintaining an aqueous dispersion of a protein-containing starting material, while under an acidic condition, with a plate-type heat exchanger using a liquid as a heat medium to make the aqueo |
| 6800742 |
Method for producing .beta.-D-ribofuranose derivatives or optical isomers thereof |
October 5, 2004 |
| The present invention provides a method for efficiently producing .beta.-D-ribofuranose derivatives or optical isomers thereof, useful as synthetic intermediates of pharmaceutical nucleic acid-series products. The method comprises a step of producing 1-O-benzyl-.beta.-D-ribofuranose- |
| 6800185 |
Method for producing basic amino acid solution |
October 5, 2004 |
| Herein are disclosed a method for producing a basic amino acid solution which comprises subjecting a solution of a basic amino acid salt to electrodialysis with the use of an electrodialyser equipped with cation exchange membranes and anion exchange membranes in combination, wherein an |
| 6794531 |
Process for production of aspartyl dipeptide ester derivative, novel production intermediate the |
September 21, 2004 |
| The present invention relates to a method of manufacturing aspartyl dipeptide ester compounds, which can be used as sweeteners, and aldehydes that can be used in the manufacturing processes. |
| 6794378 |
Heterocyclic compounds and medical use thereof |
September 21, 2004 |
| The present invention provides an AP-1 activation inhibitor, a NF-kappaB activation inhibitor, an inflammatory cytokine production inhibitor, a production inhibitor for matrix metalloprotease or an inflammatory cell adhesion factor expression inhibitor, which contains a heterocyclic |
| 6793920 |
Antithrombotic agent and anti-von willebrand factor monoclonal antibody |
September 21, 2004 |
| A monoclonal antibody, which has reactivity with human von Willebrand factor, which has action to inhibit RIPA (ristocetin-induced platelet aggregation), BIPA (botrocetin-induced platelet aggregation), and SIPA (shear stress-induced platelet aggregation) of human platelet, and which |
| 6790647 |
Mutant N-acetylglutamate synthase and method for L-arginine production |
September 14, 2004 |
| L-arginine is produced using a bacterium belonging to the genus Escherichia harboring a mutant N-acetylglutamate synthase in which the amino acid sequence corresponding to positions from 15 to 19 in a wild type N-acetylglutamate synthase is replaced with any one of amino acid sequenc |
| 6790470 |
Aspartame derivative crystal and process for producing the same |
September 14, 2004 |
| For example, N-[N-(3,3-dimethylbutyl)-L-.alpha.-aspartyl]-L-phenylalanine methyl ester (A-type crystal) showing characteristic peaks in diffractive X-ray at diffraction angles (2.theta., CuK.alpha. ray) of at least 6.0.degree., 24.8.degree., 8.2.degree. and 16.5.degree. is dried to its |
| 6787174 |
Method for manufacturing sauteed onion or sofrit in a rotary sauteing machine |
September 7, 2004 |
| The present invention relates to a method for manufacturing sauteed onion or sofrit. The method includes the steps of sauteing onion or sofrit ingredients in a rotary sauteing machine, and heating the machine with an auxiliary heater concurrently with the sauteing step, whereby the t |
| 6784315 |
Stilbene derivative crystal and method for producing the same |
August 31, 2004 |
| A Type IV crystal of (Z)-N-[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)vinyl]phenyl]-L-serinamide hydrochloride, which can be produced by crystallization using a solvent containing water at 2% by weight at the maximum and which has a X ray powder diffraction pattern containing peaks at l |
| 6784191 |
Benzamidine derivatives |
August 31, 2004 |
| A benzamidine derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an effect of inhibiting the blood coagulation based on their excellent effect of inhibiting activated blood-coagulation factor X. Thus, a blood-coagulation inhibitor or a |
| 6783788 |
Seasoning compositions, foods containing such a seasoning composition, and process for preparing |
August 31, 2004 |
| Seasoning compositions, which comprise 100 parts by weight of potassium chloride, 0.2 to 5 parts by weight of a sugar alcohol, 1 to 7.5 parts by weight of monosodium glutamate, 1 to 10 parts by weight of sucrose, and 0.05 to 1 part by weight of sodium inosinate and/or sodium guanylate, a |
| 6777396 |
Feed for livestock |
August 17, 2004 |
| A composition for livestock feed, comprising a feed for livestock and at least two additives selected from the group consisting of nucleic acid, glutamine and glutamic acid; and a method for increasing body weight gain efficiency and feed efficiency in livestock, comprising administering |
| 6777208 |
Method for producing 2' -deoxyribonucleoside |
August 17, 2004 |
| A 2'-deoxyribonucleoside is produced by culturing a microorganism, which is transformed with a gene encoding a ribonucleotide reductase and in which 2'-deoxyribonucleoside degradation activity is decreased or eliminated by disrupting a gene encoding a purine nucleoside phosphorylase on |
| 6774215 |
Method of separating and producing a lipid rich-lipid/protein complex and native proteins from o |
August 10, 2004 |
| A method of producing separated lipid-rich lipid/protein complex and native proteins from oil seeds, by adding a substance having the ability to aggregate lipids with proteins to a water extract of oil seeds, sedimenting or floating a lipid/protein complex having a lipid content of 4 |
| 6770312 |
Frozen foods and process for producing the same |
August 3, 2004 |
| The frozen food product according to the present invention contains as a major ingredient boiled rice grains or boiled pasta pieces; a water migration-preventing layer formed on the surface of each rice grain or boiled pasta; and a sauce layer formed on the surface of the water migra |
| 6770310 |
Pickle solution including transglutaminese, method of making and method of using |
August 3, 2004 |
| The present invention provides a composition having protein, transglutaminase and a transglutaminase suppressing compound such as an ammonium salt, which is useful in the preparation of pickle solutions and in methods of making processed meat products with the pickle solution. |
| 6765100 |
Method for producing epoxide crystal |
July 20, 2004 |
| The invention relates to a method for industrially producing highly pure (2R, 3S)- or (2S, 3R)-N-carbamate-protected .beta.-aminoepoxide (crystal) or (2R, 3S)- or (2S, 3R)-N-carbamate-protected .beta.-aminoalcohol. The method for producing N-carbamate-protected .beta.-aminoepoxide crysta |
| 6764545 |
Production method of epoxide crystal |
July 20, 2004 |
| The present invention provides a production method including adding water to a solution of (2R,3S)-3-tert-butoxycarbonylamino-1,2-epoxy-4-phenylbutane ((2R,3S)-epoxide compound) or (2S,3R)-3-tert-butoxycarbonylamino-1,2-epoxy-4-phenylbutane ((2S,3R)-epoxide compound) in a polar s |
| 6762041 |
Method for isotope labeling of protein with enzyme |
July 13, 2004 |
| The present invention provides a method for isotopically labeling a functional group possessed by an amino acid residue of a protein. The present invention also provides a protein whose functional group in an amino acid residue is isotopically labeled.A functional group in an amino acid |
