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Ajinomoto Co.,Inc. Patents
Assignee:
Ajinomoto Co.,Inc.
Address:
Tokyo, JP
No. of patents:
1065
Patents:




Patent Number Title Of Patent Date Issued
7015201 Pyrazole derivatives and diabetic medicine containing them March 21, 2006
The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine. ##STR00001##
7015010 Method for producing L-glutamic acid by fermentation accompanied by precipitation March 21, 2006
A microorganism which can metabolize a carbon source at a specific pH in a liquid medium containing L-glutamic acid at a saturation concentration and the carbon source, and has ability to accumulate L-glutamic acid in an amount exceeding the amount corresponding to the saturation con
7012152 Method for producing lysine derivative March 14, 2006
The present invention provides a method for industrially producing an optically active lysine derivative useful as a pharmaceutical intermediate. More particularly, the present invention provides a production method including protecting an amino group or an amino group and carboxyl g
7011860 Flavor precursor composition and method for releasing the flavor component March 14, 2006
Herein is disclosed a flavor precursor composition comprising as an active ingredient a flavor precursor compound (flavor precursor compound A) in which a volatile flavor compound having a mercapto group in the molecule and a non-volatile compound having a mercapto group in the molecule
7011845 .beta.-glucans encapsulated in liposomes March 14, 2006
Liposomes encapsulating a .beta.-glucan have an improved activity of enhancing a cellular immunity, especially when they are transmucosally administered. Thus, the liposomes are useful for the treatment or prevention of infection or tumor.
6995250 Thermophilic amino acid biosynthesis system enzyme gene of thermotolerant coryneform bacterium February 7, 2006
A plurality of primer sets are designed based on a region where conservation at the amino acid level is observed among various microorganisms for known gene sequences corresponding to a gene coding for an enzyme of the L-amino acid biosynthetic pathway derived from Corynebacterium th
6995179 Dihydropyridine derivative February 7, 2006
Dihydropyridine derivatives of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an activity of selectively inhibiting the action of N-type calcium channel. They are used as remedies for various diseases relating to the N-type calcium channel such
6992106 Anti-tumor composition January 31, 2006
The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and
6991924 Mutant carbamoylphosphate synthetase and method for producing compounds derived from carbamoylph January 31, 2006
L-arginine, citrulline and pyrimidine derivatives including orotic acid, uridine, uridine 5'-monophosphate (UMP), cytidine and cytidine 5'-monophosphate (CMP) are produced using a bacterium belonging to the genus Escherichia harboring a mutant carbamoylphosphate synthetase in which t
6987008 Variant nucleoside-5'-phosphate producing enzyme January 17, 2006
There is provided a mutant nucleoside-5'-phosphate producing enzyme with improved nucleoside-5'-phosphate producing ability of a nucleoside-5'-phosphate producing enzyme that has transphosphorylation activity and/or phosphatase activity and has one Lys residue, two Arg residues and t
6984514 Bacterium having ability to produce L-glutamic acid, L-proline or L-arginine and method for prod January 10, 2006
L-Glutamic acid, L-proline or L-arginine is produced by culturing a bacterium belonging to the genus Escherichia, which is L-isoleucine auxotrophic and has ability to produce L-glutamic acid, L-proline or L-arginine, in a medium containing L-isoleucine, to produce and accumulate L-gl
6979560 Eschericha bacteria overexpressing the yahn gene for feedback-insensitive amino acid production December 27, 2005
A bacterium belonging to the genus Escherichia and having an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing an expression amount of an L-amino acid excretion protein, and a method for producing the L-amino acid using the
6974582 Cosmetic composition December 13, 2005
Herein is disclosed a cosmetic composition comprising, as active ingredients, one or more members selected from the group consisting of mono-N.sup..alpha. -acylarginines and cosmetic powders whose surfaces have been treated with a mono-N.sup..alpha. -acylarginine (Ingredient A) and o
6969782 Method of producing transgenic plants having improved amino acid composition November 29, 2005
Transgenic plants containing free amino acids, particularly at least one amino acid selected from among glutamic acid, asparagine, aspartic acid, serine, threonine, alanine and histidine accumulated in a large amount, in edible parts thereof, and a method of producing them are provided.
6962805 Method of constructing amino acid producing bacterial strains, and method of preparing amino aci November 8, 2005
A method of producing coryneform bacteria having improved amino acid or nucleic acid productivity comprising the steps of introducing a mutation in a promoter sequence of amino acid- or nucleic acid-biosynthesizing genes on a chromosome of a coryneform bacterium to make it close to a
6960455 Methods of making amino acids using E. coli transformed with csc genes November 1, 2005
An amino acid such as threonine, homoserine, isoleucine, lysine, valine and tryptophan is produced using a bacterium belonging to the genus Escherichia which has been constructed from sucorse non-assimilative strain belonging to the genus Escherichia and which harbors sucrose non-PTS
6946268 L-cysteine producing bacterium and method for producing L-cysteine September 20, 2005
L-Cysteine is produced by culturing a bacterium belonging to the genus Escherichia having an L-cysteine producing ability and modified so that cystathionine-.beta.-lyase activity or cystathionine-.beta.-lyase activity and tryptophanase activity should be reduced or eliminated in a medium
6939987 Method for producing Aspartame derivative, method for purifying the same, crystals thereof and u September 6, 2005
N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L-.alpha.-aspartyl]-L-phenylalan ine 1-methyl ester is prepared by a process comprising: subjecting Aspartame and 3-(3-methoxy-4-hydroxyphenyl)propionaldehyde or derivatives thereof to reductive alkylation in a solvent to produce N-[N-[3-(3-me
6939894 Methods for reducing excessive barking of a dog September 6, 2005
Methods for reducing excessive barking of a dog are disclosed wherein GABA or SKF97541 is administered.
6938575 Method for treating hatching eggs and method for hatching eggs September 6, 2005
A method for treating a fertilized egg of a bird, a method for increasing the body weight of a chick at hatch, and a method for increasing the hatchability of a fertilized egg of a bird, comprising injecting, into the fertilized egg after start of incubation, a solution containing amino
6933365 Mutant tyrosine repressor proteins August 23, 2005
A gene coding for a mutant tyrosine repressor having increased positive regulatory activity for expression of the tyrosine phenol lyase gene compared with a tyrosine repressor not having mutation is obtained by introducing a mutation into a tyrosine repressor gene of Erwinia herbicol
6930205 Process for preparing aminostilbene derivatives August 16, 2005
The present invention relates to a novel process for preparing an aminostilbene derivative, which is important as an active component of anticancer drugs or an intermediate for preparation thereof, as well as methods of producing the same.
6924131 Xylitol dehydrogenase of acetic acid bacteria and gene thereof August 2, 2005
Xylitol is produced by allowing xylitol dehydrogenase or cells instoduced with a DNA coding for xylitol dehydrogenase, which is a protein of the following (A) or (B) to act on D-xylulose, and collecting produced xylitol: (A) a protein which has the amino acid sequence of SEQ ID NO: 4;
6921747 Basic amino acid derivatives July 26, 2005
The present invention provides a basic amino acid derivative represented by the formula (1): ##STR1##The present invention also provides a method of making a gelled product by employing the aforementioned compound, as well as a gel, perfumery, and/or cosmetic containing the same.
6914151 Crystallization processes for the formation of stable crystals of aspartame derivative July 5, 2005
A crystallization process for forming a stable crystal of N-(3,3-dimethylbutyl)-APM, which comprises using either water or a mixture of water with a lower alcohol as the crystallizing solvent and controlling the crystallization point to 30.degree. C. or above; and another crystalliza
6914075 Cystine derivative and agent for suppressing activation of inflammatory factors July 5, 2005
The present invention provides cystine derivatives, which may be in a free form, a salt form, a solvate form. The cystine derivatives of the present invention may be used to suppress activation of inflammatory factors. Accordingly, the present invention provides: compositions containing
6911332 Isolated polynucleotides encoding d-arabino-3-hexulose-6-phosphate synthases from Methylophilus June 28, 2005
The present invention provides polypeptides and polynucleotides involved in C1 assimilation in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides.
6910410 Method and apparatus for manufacturing charcoal grilled foods June 28, 2005
A method and apparatus for manufacturing charcoal grilled foods including a forge conveyer loading and transferring charcoals burning after firing, a temperature sensor detecting the heating power on the forge, a continuous type forge of a charcoal fire consisting of an air blower to kee
6908905 N-substituted pyrazole-O-glycoside derivatives and therapeutic agent for diabetes containing the June 21, 2005
The present invention relates to pyrazole derivatives represented by the following formulas and analogues thereof, which can be used for a therapeutic agent for diabetes. ##STR1##
6908754 Carbamoyl-phosphate synthetase gene of coryneform bacteria and method for producing L-arginine June 21, 2005
A DNA fragment which encodes a polypeptide defined in the following (a) or (b), and a polypeptide defined in the following (c) or (d): (a) a polypeptide which has at least the amino acid sequence of the amino acid numbers 50 to 393 in SEQ ID NO: 2 shown in Sequence Listing, (b) a polyp
6906224 Process for producing .alpha.-aminoketones June 14, 2005
A process for producing .alpha.-aminohalomethyl ketones or N-protected .alpha.-aminohalomethyl ketones from specified 3-oxazolidin-5-one derivatives via 5-halomethyl-5-hydroxy-3-oxazolidine derivatives. By this process, .alpha.-aminohalomethyl ketones and compounds relating to them c
6905819 Plasmid autonomously replicable in coryneform bacteria June 14, 2005
A plasmid which is able to be isolated from Corynebacterium thermoaminogenes, and which comprises a gene coding for a Rep protein having the amino acid sequence shown in SEQ ID NO: 4 or an amino acid sequence having homology of 90% or more to the amino acid sequence shown in SEQ ID N
6903149 Composition for wood-polymer composite and wood-polymer composite made from the composition June 7, 2005
The present invention provides a composition for wood-polymer composites containing a thermoplastic resin, wood flour and a polyol ester compound having not less than one hydroxyl group esterified with fatty acid, and a wood-polymer composite made from this composition. According to the
6899912 Method for producing aspartame derivative, method for purifying the same, crystals thereof and u May 31, 2005
N-[N-[3-(3-methoxy-4-hydroxyphenyl)propyl]-L-.alpha.-aspartyl]-L-phenylalan ine 1-methyl ester is prepared by a process comprising: subjecting Aspartame and 3-(3-methoxy-4-hydroxyphenyl)propionaldehyde or derivatives thereof to reductive alkylation in a solvent to produce N-[N-[3-(3-me
6897048 Microorganisms and method for L-arginine production by fermentation May 24, 2005
The present invention relates to a microorganism having an L-arginine producing ability where the microorganism synthesizes L-arginine through the biosynthetic linear or cyclic pathway and contains a recombinant DNA containing the argJ gene encoding an enzyme having ornithine acetylt
6893852 Dna encoding sucrose pts enzyme II May 17, 2005
A gene encoding a protein constituting sucrose PTS of coryneform bacterium is provided by amplifying a region existing downstream from sucrase gene in coryneform bacterium by the cassette-ligation mediated PCR to obtain DNA encoding sucrose PTS enzyme II, which is a protein defined in th
6891084 DNA encoding raffinose synthase from soybean May 10, 2005
The present invention provides a DNA encoding a raffinose synthase from soybean and vectors containing the same. Also provided are plants and host cells transformed with the DNA sequence and methods of altering the levels of raffinose family oligosaccharides in plants.
6888012 Process for producing optically active halohydrin compound May 3, 2005
A process of preparing an optically active halohydrin compound characterized by comprising asymmetric hydrogen transfer reduction of an .alpha.-haloketone compound in the presence of a group 9 transition metal compound having a substituted or unsubstituted cyclopentadienyl group and
6887691 DNA coding for protein which confers on bacterium Escherichia coli resistance to L-homoserine, a May 3, 2005
A bacterium which has an ability to produce an amino acid and in which a novel gene (rhtB) coding for a protein having an activity of making a bacterium having the protein L-homoserine-resistant is enhanced, is cultivated in a culture medium to produce and accumulate the amino acid in
6881861 Method of purifying glutamic acid by transition recrystallization April 19, 2005
Disclosed herein is a method of purifying L-glutamic acid by transformation recrystallization which method comprises maintaining crude crystals of L-glutamic acid containing .alpha. crystals of L-glutamic acid in an aqueous solvent at a temperature of from 50.degree. C. to the boiling
6881566 Carbamoyl-phosphate synthetase gene of coryneform bacteria and method for producing L-arginine April 19, 2005
A DNA fragment which encodes a polypeptide defined in the following (a) or (b), and a polypeptide defined in the following (c) or (d): (a) a polypeptide which has at least the amino acid sequence of the amino acid numbers 50 to 393 in SEQ ID NO: 2 shown in Sequence Listing, (b) a polyp
6881293 Process for producing a multi-layer printer wiring board April 19, 2005
The present invention is directed to an inter-laminar adhesive composition containing a liquid epoxy resin, a polyfunctional epoxy resin having a softening point higher than a lamination temperature of the adhesive and with two or more epoxy groups within the molecule; and a latent epoxy
6878811 Substance with antithrombotic activity and method for detecting glycokallidin April 12, 2005
A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by
6878533 Gene encoding dihydrodipicolinate synthase from Bacillus methanolicus and methods of making lysi April 12, 2005
An Escherichia coil mutant strain deficient in dihydrodipicolinate synthase or dihydrodipicolinate reductase is transformed by using a chromosome gene library of Bacillus methanolicus, a transformant strain which can grow on a minimal medium is selected, and recombinant DNA containing DN
6872703 Insulin receptor-related receptor binding protein March 29, 2005
A protein or a variant thereof, which has a binding activity to IRR and the following characteristics and an insulin receptor-related receptor are allowed to bind in the presence of a test substance, and inhibition of the binding is measured to search for an agonist or antagonist of IRR
6869933 HIV-specific CTL inducing peptides and medicaments for preventing or treating AIDS comprising th March 22, 2005
Peptides which can induce specific CTLs for HIV, DNAs encoding for the peptides and medicaments for preventing and/or treating HIV comprising the peptides are provided. According to the present invention, peptides carrying novel CTL epitopes derived from HIV Pol or Env proteins are p
6869911 Tillering promoter for plant and method for tillering promotion of plant March 22, 2005
Herein are disclosed a tillering promoter for a plant comprising an amino acid, especially proline, or inosine in addition thereto, as effective ingredient(s), and a method for tillering promotion for a plant wherein the tillering promoter is especially applied onto the leaf surfaces, in
6867397 Heating apparatus and heating stabilization device in thereof March 15, 2005
A heating apparatus includes a steel belt conveyer having a steel belt with a top part that transports and heats, and induction heating coils having an elliptical or a rectangular shape disposed under or over the top part of the steel belt such that the longitudinal direction of each of
6858405 Process for producing protein hydrolyzate February 22, 2005
The present invention relates to a method which can prevent browning of hydrolyzed protein obtained by enzymatic hydrolysis of vegetable protein material.A vegetable protein material containing saccharides is mixed with the fungal culture and is subjected to enzymatic hydrolysis in a liq
6858244 Seasoning compositions, foods and drinks with the use thereof and processes for producing the sa February 22, 2005
The present invention relates to a seasoning composition that suppresses unpleasant acidic tastes or acidic smells present in or generated by foods and drinks, especially foods, and a process for producing the same.

 
 
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