| Patent Number |
Title Of Patent |
Date Issued |
| 7153963 |
Phenylalanine derivatives |
December 26, 2006 |
| Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to .alpha.4 integrin. They are used as therapeutic agents for various diseases concerning .alpha.4 integrin ##STR00001## |
| 7153850 |
Lactam compounds and pharmaceutical use thereof |
December 26, 2006 |
| An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound |
| 7148371 |
Method for producing lysine derivative |
December 12, 2006 |
| The present invention provides a method for industrially producing an optically active lysine derivative useful as a pharmaceutical intermediate. More particularly, the present invention provides a production method including protecting an amino group or an amino group and carboxyl g |
| 7148069 |
Method for analysis of compounds with amino group and analytical reagent therefor |
December 12, 2006 |
| The present invention provides a method for the analysis of a compound with amino group (e.g., an amino acid or peptide) contained in a sample and convenient manner with a high sensitivity. The compound with amino group in a sample containing the compound with amino group is labeled |
| 7148047 |
L-cysteine producing bacterium and method for producing L-cysteine |
December 12, 2006 |
| L-cysteine is produced by culturing a coryneform bacterium in which intracellular serine acetyltransferase activity is increased by transformation with a gene coding for serine acetyltransferase, such modification of an expression control sequence of a gene coding for serine acetyltr |
| 7145030 |
Production method for optically active N-aryl-.beta.-amino acid compounds |
December 5, 2006 |
| The present invention provides an effective method for the production of optically active N-aryl-.beta.-amino acid compounds, which at the same time is suitable for industrial production. In the method of the present invention optically active sulfonylated .beta.-hydroxycarboxylic acid |
| 7141263 |
Process for producing cinnamaldehyde derivatives, use thereof and the like |
November 28, 2006 |
| A process for conveniently and efficiently producing a highly pure cinnamaldehyde derivative, for example, (2E)-(3-hydroxy-4-methoxy)cinnamaldehyde, which comprises reacting a benzaldehyde derivative, such as isovanillin and the like, with acetaldehyde in the presence of an alkali, i |
| 7138266 |
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine |
November 21, 2006 |
| A bacterial strain of Escherichia coli is described which produces L-threonine, and is obtained by a process comprising transduction by bacteriophage P1 which bears a transposon which inactivates threonine dehydrogenase activity, and isolation of a transductant lacking threonine dehy |
| 7138142 |
Process for producing granules containing branched amino acids |
November 21, 2006 |
| The problem of the present invention is to provide pharmaceutical granules containing, as active amino acid ingredients, three kinds of branched chain amino acids of isoleucine, leucine and valine, which has a smaller specific volume than conventional products, and a production method |
| 7138116 |
Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody |
November 21, 2006 |
| Anti-thrombotic agents containing humanized antibodies which bind to von Willebrand factor. |
| 7128939 |
Pretreatment agent for a fish food |
October 31, 2006 |
| The present invention is a pretreatment agent for a fish food which comprises, in a mixture, 1 30% (v/v) of ethanol, 5 25% (w/v) of citrate and 0.5 50% (w/v) of at least one inorganic salt selected from the group consisting of phosphate, carbonate and bicarbonate, and a process for p |
| 7125977 |
Genes for heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic co |
October 24, 2006 |
| A plurality of primer sets are designed based on a region where conservation at the amino acid level is observed among various microorganisms for known gene sequences corresponding to a gene coding for an enzyme of the L-amino acid biosynthetic pathway derived from Corynebacterium th |
| 7122696 |
Processes for preparation of N-protected-.beta.-amino alcohols and N-protected-.beta.-amino epox |
October 17, 2006 |
| Herein are disclosed a process for increasing in purity, or purifying, an N-protected-.beta.-aminoalcohol which process comprises (i) adding water to a polar organic solvent in which an N-protected-.beta.-aminoalcohol such as a (2R,3S)- or (2S,3R)-3-tert-butoxycarbonylamino-1-halo-2- |
| 7118775 |
Process for producing a flavor-enhancing material for foods |
October 10, 2006 |
| The present invention relates to a method for producing a cysteine-rich food material by maintaining a food material containing .gamma.-glutamylcysteine at a ratio of at least 1 wt % to the solid content thereof at a temperature ranging from 50 to 120.degree. C. and at a pH ranging f |
| 7115389 |
Method for producing dipeptide |
October 3, 2006 |
| A method for producing a dipeptide including the step of exposing a carboxy component and an amine component to an enzyme having an activity to hydrolyze amino acid ester. Such a hydrolase has been found among enzymes in bacteria. The method is useful for producing a peptide simply a |
| 7115296 |
N-alkylaspartyl amide derivative and sweetening agent |
October 3, 2006 |
| The present invention relates to a novel N-alkylaspartyl amide derivative, a salt form thereof, a sweetening agent containing the same and a sweetened food or drink containing the N-alkylaspartyl amide derivative as an effective ingredient. |
| 7112431 |
5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optic |
September 26, 2006 |
| The present invention relates to a 5-substituted hydantoin racemase, which efficiently catalyzes racemization reactions at a high optimum temperature for racemization reactions, DNA coding for the racemase, and processes for producing optically active amino acids. |
| 7108884 |
Process for producing cysteinylglycine-enriched food material and process for producing flavor-e |
September 19, 2006 |
| Disclosed in this application are a method for producing a food material containing cysteinylglycine at a high content, which comprises the step of (a) maintaining a starting food material containing glutathione in a ratio of 1% by weight or more based on the solid content at a temperatu |
| 7105570 |
Cysteine derivatives |
September 12, 2006 |
| Objects of the present invention are to provide an oxidative stress inhibitor which is capable of suppressing the expression of a cytotoxic protein and the activation of a gene transcriptional regulatory factor taking part such expression of a cytotoxic protein and exhibits good feel |
| 7105520 |
Phenylalanine derivatives |
September 12, 2006 |
| Phenylalanine derivatives of the following formulae and analogues thereof have an antagonistic activity to .alpha.4 integrin. They are used as therapeutic agents for various diseases concerning .alpha.4 integrin ##STR00001## |
| 7098020 |
DNA encoding hydantoinase, DNA encoding N-carbamyl-L-amino acid hydrolase, recombinant DNA, tran |
August 29, 2006 |
| The present invention provides a method of producing optically active amino acids from 5-substituted hydantoin by isolating a hydantoinase gene and an N-carbamyl-L-amino acid hydrolase gene involved in an ability to convert 5-substituted hydantoin or N-carbamylamino acid into optically |
| 7098019 |
DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, re |
August 29, 2006 |
| DNA for encoding a protein having D-hydantoinase activity which has a base sequence represented by Sequence ID No. 1 in the Sequence Listing. DNA for encoding a protein having D-carbamylase activity which has a base sequence represented by Sequence ID No. 3 in the Sequence Listing. |
| 7097999 |
Method for producing target substance using microorganisms with reduced interactions between Mal |
August 29, 2006 |
| The present invention describes a method for producing a target substance by utilizing a microorganism comprising culturing the microorganism in a medium, allowing the target substance to accumulate, and collecting the target substance from the medium. Also the microorganism used in the |
| 7097869 |
Nutraceutical chips and production method thereof |
August 29, 2006 |
| In this application are disclosed a method for producing nutraceutical chips, comprising the steps of: preparing a viscous liquid by use of at least one selected from the group consisting of vegetables, fruits, seeds, nuts and seaweeds which may have been heat-treated in advance as d |
| 7094797 |
Organ fibrosis inhibitor |
August 22, 2006 |
| An organ fibrosis inhibitor, in particular, a liver fibrosis inhibitor is provided, which contains histidine, preferable together with cysteine and/or cystine as active ingredients. Owing to the combined use, a remarkable effect of inhibiting organ fibrosis, in particular, liver fibr |
| 7091221 |
Partial ester of cellulose with nitrogenous carboxylic acid and process for producing the same |
August 15, 2006 |
| According to the present invention, there are provided a novel partial ester of a nitrogenous carboxylic acid ester with cellulose, the partial ester being useful as an antibacterial agent, a flame retardant, etc., and a simple and convenient process for preparing the same. Fibers made |
| 7090998 |
Method for producing target substance by fermentation |
August 15, 2006 |
| In a method for producing a target substance utilizing a microorganism, which comprises culturing a .gamma.-proteobacterium in a medium to produce and accumulate the target substance in the medium or cells and collecting the target substance, there is used a strain in which the ArcA |
| 7087422 |
Aminopeptidase and the genes thereof |
August 8, 2006 |
| The object of the present invention is to provide Koji mold aminopeptidases capable of efficiently hydrolyzing persistent peptides and also genes encoding the aminopeptidases. The present invention provides Aspergillus nidulans aminopeptidase and nucleic acid molecules encoding it. I |
| 7084113 |
Protein having antithrombotic activity and method for producing the same |
August 1, 2006 |
| A method for producing a protein having an antithrombotic activity, which comprises replacing, in a protein that has an amino acid sequence having a homology of not less than 30% to the amino acid sequence of SEQ ID NO: 1 and forms a higher order structure composed of a first .beta. stra |
| 7078590 |
Method for providing a property of stress-resistance |
July 18, 2006 |
| The present invention enables production of a plant resistant to environmental stresses including drought stress. The invention increases stress resistance to a plant by increasing raffinose content in the plant. |
| 7064307 |
Container commonly usable for electromagnetic cooking heaters and microwave ovens |
June 20, 2006 |
| A container commonly usable for electromagnetic cooking heaters and microwave ovens. A resin container commonly usable for electromagnetic cooking heaters and microwave ovens having an aluminum thin, film on the bottom thereof for storing food therein. The aluminum thin film is 5 30 |
| 7064219 |
Processes of producing glutamic acid compounds and production intermediates therefore and novel |
June 20, 2006 |
| The present invention relates to processes of producing glutamic acid compounds, for example, monatin, which are useful as, for example, production intermediates for sweetener or pharmaceutical products. |
| 7060485 |
DNA for encoding D-hydantoin hydrolases, DNA for encoding N-carbamyl-D-amino acid hydrolases, re |
June 13, 2006 |
| DNA for encoding a protein having D-hydantoinase activity which has a base sequence represented by Sequence ID No. 1 in the Sequence Listing. DNA for encoding a protein having D-carbamylase activity which has a base sequence represented by Sequence ID No. 3 in the Sequence Listing. |
| 7060475 |
Polynucleotides encoding polypeptides involved in intermediates metabolism of central metabolic |
June 13, 2006 |
| The present invention provides polypeptides and polynucleotides involved in central intermediates metabolism in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. |
| 7052884 |
L-arginine producing Escherichia coli and method of producing L-arginine |
May 30, 2006 |
| Arginine can be efficiently produced by cultivating Escherichia coli which has an ability to produce arginine and an ability to utilize acetate in a culture medium to produce and accumulate arginine in the medium, and collecting arginine from the medium. |
| 7052630 |
Resin additive composition and process for producing the same |
May 30, 2006 |
| In this application is disclosed a resin additive composition which can by produced by precipitating a calix(n+m+l)arene represented by the following general formula (2) and in a dissolved state together with or at the same time at least one functional ingredient selected from the gr |
| 7045320 |
Methods for producing L-amino acids |
May 16, 2006 |
| A bacterium belonging to the genus Escherichia having an ability to produce an L-amino acid is cultured in a medium containing fructose as a main carbon source, preferably a medium containing a carbon source composed of 30 weight % or more of fructose and 70 weight % or less of gluco |
| 7037690 |
Method for producing L-amino acid |
May 2, 2006 |
| In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and collecting the L-amino acid from the medium, a Gram-negative bacterium having the Entner-Doudoroff |
| 7037673 |
Dipeptide production method, L-amino acid amide hydrolase used therein, and production method of |
May 2, 2006 |
| A process for industrially advantageously producing a dipeptide via a convenient pathway starting with less expensive and easily available materials is provided. A dipeptide is produced from an L-amino acid amide and an L-amino acid by using a culture of a microbe capable of synthesi |
| 7037586 |
Film for circuit board |
May 2, 2006 |
| The present invention relates to a film for a circuit board characterized in that the following A layer is adjacent to the following B layer is disclosed in the present application. A circuit board excellent in adhesion strength of a conductor layer can easily be produced by using th |
| 7037548 |
Soybean embryo fat/oil and process for producing soybean material with high embryo concentration |
May 2, 2006 |
| The purpose of the present invention is to extract oil from the soybean material containing soybean germ as a main component, and to utilize it.The present invention relates to a method for producing a soybean material, comprising crudely crushing selected soybeans into a size of les |
| 7033802 |
Penicillin binding protein gene and process for producing L-glutamic acid |
April 25, 2006 |
| The present invention relates to a penicillin binding protein, DNA encoding the protein and methods of producing L-glutamic acid in Corynebacterium glutamicum, which has a reduction of penicillin binding protein activity. |
| 7030268 |
Methods for producing acylphenylalanine |
April 18, 2006 |
| There is provided a method for producing easily highly-purified acylphenylalanine that is useful as a raw material of pharmaceutical products and the like, which comprises the step of reacting an acid chloride with phenylalanine in a mixed solvent of an organic solvent and water, whi |
| 7030222 |
Human gastric cancer antigen gene and gastric cancer antigen protein |
April 18, 2006 |
| A tumor antigen gene is identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen specific cytotoxic T cell (CTL) by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric canc |
| 7029896 |
Phosphoserine phosphatase gene of coryneform bacteria |
April 18, 2006 |
| The present invention provides a DNA coding for a protein defined in the following (A) or (B) is obtained from Brevibacterium flavum chromosomal DNA library by cloning a DNA fragment that complicates serB deficiency of Escherichia coli as a open reading frame in the DNA fragment.(A) A |
| 7029893 |
Polynucleotides encoding polypeptides involved in amino acid biosynthesis in methylophilus methy |
April 18, 2006 |
| The present invention provides polypeptides and polynucleotides involved in amino acid biosynthesis in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynucleotides. |
| 7026149 |
Polynucleotides encoding polypeptides involved in the stress response to environmental changes i |
April 11, 2006 |
| The present invention provides polypeptides and polynucleotides involved in the stress response to environmental changes in Methylophilus methylotrophus and methods of producing amino acids in microorganisms having enhanced or attenuated expression of these polypeptides and/or polynu |
| 7026003 |
Processes for preparing an aspartame slurry |
April 11, 2006 |
| The present invention provides processes for preparing a slurry containing aspartame, which is stable and is useful as a sweetener; as well as methods of assessing the stability of an aspartame slurry. |
| 7022863 |
Production method of pyrrolidone carboxylic acid and salt thereof |
April 4, 2006 |
| The present invention provides a production method of pyrrolidone carboxylic acid or a salt thereof, which includes bringing glutamic acid or a salt thereof into contact with high-temperature high-pressure water having a temperature of above 100.degree. C. and not higher than 300.deg |
| 7022339 |
Antidiabetic preparation for oral administration |
April 4, 2006 |
| There is provided a single preparation which directly decreases both of the post prandial blood glucose level and the fasting blood glucose level close to normal levels, by release-sustaining a drug capable of decreasing the post prandial blood glucose level of diabetic patients clos |
