| Patent Number |
Title Of Patent |
Date Issued |
| 4377512 |
Oxygen carrier for blood substitute |
March 22, 1983 |
| A hemoglobin modified by covalently bound inulin. |
| 4371614 |
E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L- |
February 1, 1983 |
| A bacterium which comprises a host of the genus Escherichia deficient in the enzyme tryptophanase carrying a plasmid with genetic information to control L-tryptophan production is useful for the fermentative production of L-tryptophan in high yields. |
| 4323563 |
Fat emulsion for intravenous injection |
April 6, 1982 |
| A pharmaceutically acceptable emulsifier for preparing fat emulsions for intravenous injection comprising purified phospholipid of vegetable origin, containing less than 5% of glycolipid, and having a degree of hydrogenation of 30-50 as defined by the iodine number is prepared from v |
| 4309341 |
Method for purifying .alpha.- L-aspartyl-L-phenylalanine lower alkyl ester |
January 5, 1982 |
| A method for purifying an .alpha.-L-aspartyl-L- phenylalanine lower alkyl ester containing impurities. The .alpha.-L-aspartyl-L-phenylalanine lower alkyl ester is brought into contact with a Cl-type anion exchange resin in an aqueous medium to have the impurities adsorbed by the anion ex |
| 4303650 |
Process for production of erythropoietin |
December 1, 1981 |
| The invention provides a novel process for the production of erythropoietin, which is a promising medicine for curing anemia, from human urine containing the same. The inventive method comprises adjusting the pH value of the urine in the range from 6 to 8, if the pH value of the urin |
| 4297279 |
Imidazoledicarboxylic acid derivative |
October 27, 1981 |
| A reactive derivative of imidazolecarboxylic acid having the formula: ##STR1## is useful in preparing imidazoledicarboxylic acid derivatives of alpha-aminopenicillins and cephalosporins. |
| 4284721 |
Method for manufacturing dipeptides |
August 18, 1981 |
| An improvement in a method for manufacturing dipeptides from an N-substituted aspartic acid and a phenylalanine lower alkyl ester. The two starting materials are allowed to react with each other in the presence of an immobilized metallo-proteinase in an organic solvent immiscible with |
| 4273684 |
Transparent detergent bar |
June 16, 1981 |
| A transparent detergent bar possessing good foaming power and detergency in hard water is formulated consisting essentially of at least one salt of a N-long chain acyl-optically active acidic amino acid neutralized with a basic amino acid in the ratio of 1 mol of the former to 1 to 2 mol |
| 4258072 |
Mixed seasoning |
March 24, 1981 |
| A mixed seasoning, comprising 100 parts by wt. monosodium glutamate; 0.05 to 25 parts by wt. of a flavor inducing 5'-nucleotide; 5.0 to 38.0 parts by wt. table salt; 0.1 to 0.87 parts by wt. succinic acid and/or sodium succinate; and 0.5 to 10.0 parts by wt. of at least one alkali salt o |
| 4257939 |
Peptide derivative |
March 24, 1981 |
| A peptide derivative useful as substrates for determining enzymatic activities have the following formula ##STR1## wherein R.sub.1 is a group selected from the group consisting of seryl, phenylalanyl-seryl, threonyl and leucyl-threonyl groups, and R.sub.2 is ##STR2## |
| 4216240 |
Process for preparing fibrous protein food products |
August 5, 1980 |
| A process for preparing an oriented fibrous protein product which comprisesholding a flowable mixture of protein-containing materials in an injection machine and then injecting said flowable mixture through a nozzle at ram pressures between 500 and 3000 kg/cm.sup.2 into an environment at |
| 4191809 |
Method of measuring enzymatic activity using novel peptide derivatives |
March 4, 1980 |
| The compound 7-glycylprolylamino-4-methylcoumarin and certain of its derivatives are utilized for the diagnosis of pathological conditions such as hepatic diseases and gastric cancer by measuring the enzymatic activity of X-prolyl dipeptidyl-aminopeptidase. |
| 4191808 |
Method of measuring dipeptidyl-amino-peptidase activity |
March 4, 1980 |
| The activity of X-prolyl dipeptidyl-aminopeptidase against X-L-proline-Y wherein X is an amino acid residue and Y is p-nitroaniline, p-phenylazoaniline or 4-phenylazo-1-naphthylamine is used as a measure of human afflictions such as hepatobiliary diseases and carcinomas. |
| 4176009 |
Method of measuring collagenase activity |
November 27, 1979 |
| A method of measuring collagenase activity using as substrates peptide derivatives having the structure A-Pro-B-Gly-C-Ala-Gly-E wherein A is a hydrophobic neutral or acidic chromophore, B is an amino acid residue, C is Ile or Leu, E is Gln-D-Arg-OH or D-Arg-OH and all the amino acid |
| 4169764 |
Process for production of urokinase |
October 2, 1979 |
| Method for the isolation of urokinase from human urine in which the urokinase is adsorbed and thereafter eluted with aqueous cation surfactant mixture. Novel carboxyalkyl cellulose is utilized as a preferred adsorbent. |
| 4160824 |
Insect attractive compositions |
July 10, 1979 |
| Insect attractive compositions contain acid-hydrolyzed defatted cereals (protein hydrolysis percent .gtoreq.70%) which have been neutralized (pH 5 to 9), preferably, after being concentrated 2 to 10 times in strongly acidic media. |
| 4147692 |
Novel dipeptide derivatives, and method of measuring enzymatic activity |
April 3, 1979 |
| The compound 7-glycylprolylamino-4-methylcoumarin and certain of its derivatives are utilized for the diagnosis of pathological conditions such as hepatic diseases and gastric cancer by measuring the enzymatic activity of X-prolyl dipeptidyl-aminopeptidase. |
| 4138394 |
Peptide derivatives and a method of measuring collagenase activity |
February 6, 1979 |
| Peptide derivatives are obtained by eliminating the masking groups from masked peptide derivatives in which the guanidino group of an arginine residue and the carboxyl group of the arginine residue are masked. The guanidino group can be masked, for example, with a tosyl, nitro or ben |
| 4138271 |
Process for preparing caramel |
February 6, 1979 |
| A process for preparing coloring caramel from a pre-gelatinized starch or dextrin. The process comprises preparing a pre-gelatinized starch or dextrin having a specified moisture content and having a specified acidic pH value and extruding it at an elevated temperature and pressure c |
| 4119620 |
Novel dipeptide derivatives, salts thereof, and method of measuring enzyme activity |
October 10, 1978 |
| The activity of X-prolyl dipeptidyl-aminopeptidase against X-L-proline-Y wherein X is an amino acid residue and Y is p-nitroaniline, p-phenylazoaniline or 4-phenylazo-1-naphthylamine is used as a measure of human afflictions such as hepatobiliary diseases and carcinomas. |
| 4113716 |
Process for preparing improved soy protein materials |
September 12, 1978 |
| A process particularly designed to further improve soy protein previously denatured by superheating treatment or alcohol extraction comprises heating an aqueous slurry of the denatured, defatted soybean flake material under prescribed conditions. Nitrogen values, flavor and color are |
| 4106989 |
Thermostable cellulase and a method for producing the same |
August 15, 1978 |
| The present invention relates to a newly found thermostable cellulase of Sporotrichum cellulophilum and a method for producing the same. |
| 4102672 |
Herbicidal composition of amino acid higher alkyl ester type and method for controlling weeds |
July 25, 1978 |
| A herbicidal composition comprising a herbicidal amount of an active compound selected from the group consisting of acid addition salts of higher alkyl esters of amino acids, acid addition salts of N-lower alkyl substitution products of said esters and quaternary ammonium salts of N- |
| 4072687 |
Process for producing 2-amino-(2)-thiazoline-4-carboxylic acid |
February 7, 1978 |
| 2-Amino-(2)-thiazoline-4-carboxylic acid is prepared by dehydrochlorinating S-(.beta.-carboxy-.beta.-chloroethyl) isothiourea by adding it to an aqueous medium maintained at a pH ranging from 5.5 to 7.5 with an alkali. |
| 4071511 |
Method of removing formyl groups from N-formyl-amino acid and N-formyl-peptide esters having fre |
January 31, 1978 |
| The masking N-formyl group of an N-formyl-amino acid ester or an N-formyl-peptide ester having a free carboxyl group is removed without major side reactions when the ester is contacted with a strong acid in a mixture of water and a specific organic solvent such as methyl ethyl ketone |
| 4071405 |
Method of producing sulfur containing L-amino acids |
January 31, 1978 |
| Method for the production of substituted sulfur containing L-amino acids by contacting .beta.- or .gamma.-substituted amino acids in an aqueous medium containing methioninase together with the precursor of the substituent. |
| 4066793 |
Seasoning composition and preparation thereof |
January 3, 1978 |
| Seasoning compositions, and processes for their production, which have an improved and enhanced meat-like flavor, and comprise mixtures containing extracts of yeast autolysates, 5'-nucleotides, sodium chloride and potassium salts; the potassium ion concentration being more than 0.5 times |
| 4066502 |
Method of producing carbon source for fermentation |
January 3, 1978 |
| A hydrolyzate of molasses, containing both glucose and fructose, is mixed with calcium hydroxide, and a fructose addition precipitate is recovered. The residual liquor is neutralized, calcium ions are removed, and then the liquor is used as a carbon source for glutamic acid or lysine |
| 4066501 |
Method for producing L-lysine by fermentation |
January 3, 1978 |
| L-lysine produced by Brevibacterium or Corynebacterium mutants that are resistant to .alpha.-aminolauryllactam, .gamma.-methyl-lysine or N.sup..omega. -carbobenzoxy lysine. |
| 4059572 |
Mucopolysaccharide having flocculating activity of protein and method for producing the same |
November 22, 1977 |
| Microorganisms of the genus Aspergillus produce mucopolysaccharides having flocculating activity for protein. |
| 4040906 |
Method of producing carbon source for citric acid fermentation |
August 9, 1977 |
| A sugar hydrolyzate, containing both glucose and fructose, is mixed with calcium hydroxide, and a fructose addition precipitate is recovered. The residual liquor is neutralized, calcium ions are removed, and then the liquor is used as a carbon source for citric acid fermentation.The pres |
| 4032325 |
Method for controlling weeds with amino acid higher alkyl esters |
June 28, 1977 |
| A herbicidal composition comprising a herbicidal amount of an active compound selected from the group consisting of acid addition salts of higher alkyl esters of amino acids, acid addition salts of N-lower alkyl substitution products of said esters and quaternary ammonium salts of N- |
| 4022666 |
Alpha-amylases from Bacillus subtilis |
May 10, 1977 |
| Alpha-amylases which have optimum activity between pH 6.5 to 8 and between pH 9.0 to 11.5 at 40.degree. C are produced by culturing strains of Bacillus subtilis on a nutrient medium under aerobic conditions. Some of the alpha amylases are effective in hot and alkaline detergent solutions |
| 4021418 |
Method of removing formyl groups from N-formyl-amino acid and N-formyl-peptide esters |
May 3, 1977 |
| The masking N-formyl group of an N-formyl-amino acid ester or N-formyl-peptide ester is removed without major side reactions when the ester is reacted in an inert liquid medium with hydroxylamine of which at least 70% is present in the form of a salt with a strong acid, the remainder |
| 4016037 |
Method for producing L-amino acid |
April 5, 1977 |
| L-amino acids are produced by fermenting a hydantoin compound with Flavobacterium aminogenes or its enzymes. |
| 4013800 |
4-Hydroxy-5-methyl-2,3-dihydrofuran-3-one and methods of making and using the same |
March 22, 1977 |
| 4-Hydroxy-5-methyl-2,3-Dihydrofuran-3-one is produced by Maillard reaction between xylose, ribose or arabinose with glutamic acid, aspartic acid, alanine, glycine, proline or salts of these amino acids, and may be recovered in crystalline form from the reaction mixture by steam disti |
| 4010258 |
Microbial amylase inhibitor and preparation thereof with the use of streptomyces diasticus var. |
March 1, 1977 |
| A new amylase inhibitor, called Amylostatin-A, which can be distinguished from those disclosed heretofore on the basis of its constitution, molecular weight, specificity for certain types of amylase and adsorbability, is obtained by cultivating a strain of actinomycetes belonging to |
| 4008306 |
Method of recovering manganese values from a mixture obtained by catalytically oxidizing a paraf |
February 15, 1977 |
| When paraffins having a chain of 10 - 40 carbon atoms are reacted with gaseous oxygen in the presence of a manganese bearing catalyst, manganese is present in the oxidation mixture partly as a solute in the liquid mixture, and partly as a sludge. When the oxidation mixture is extracted |
| 4006057 |
Method of producing L-cysteine and L-cystine |
February 1, 1977 |
| A method for producing L-cysteine and/or L-cystine which comprises:A. holding 2-amino-thiazoline-4-carboxylic acid in an aqueous solution at a pH of 5 to 11 in the presence of an effective amount of enzyme produced by a microorganism; said enzyme being capable of converting the 2-amino-t |
| 4000040 |
Method for producing L-aspartic acid by fermentation |
December 28, 1976 |
| L-Aspartic acid is produced by culturing an L-aspartic acid producing mutant strain which is resistant to 6-(dimethylamino)-purine and which is derived from a parent strain belonging to the genus Brevibacterium or Corynebacterium in an aqueous culture medium and then recovering the L |
| 3996288 |
Method of producing aldehydes by hydroformylation |
December 7, 1976 |
| When an alcohol or its hydrochloric or hydrobromic acid ester is held at 50.degree. to 200.degree. C and 10 to 500 atmospheres in the presence of hydrogen, carbon monoxide, the amide of a carboxylic acid, and a carbonylation catalyst, an aldehyde having one more carbon atom than the |
| 3993543 |
Process for producing pyruvic acid by fermentation |
November 23, 1976 |
| Improved method for producing pyruvic acid by fermentation of pyruvic acid producing mutants of the strain Candida lipolytica which require methionine and thiamine for growth. |
| 3991077 |
Method of racemizing optically active N-acylamino acids |
November 9, 1976 |
| Optically active amino acids N-acylated with carboxylic acids are readily racemized without decomposition at elevated temperature in inert organic solvents in which they are homogeneously soluble at the racemization temperature. When the deacylated amino acid is insoluble or only sparing |
| 3985722 |
Process for preparing N-higher aliphatic acyl derivatives of amino acids, peptides or proteins |
October 12, 1976 |
| A mixed acid anhydride consisting of higher fatty acid having 6 to 22 carbon atoms and sulfuric anhydride is reacted with amino acids, peptides or proteins in the presence of a base to form N-higher aliphatic acyl derivatives of amino acids, peptides or proteins respectively in good |
| 3985617 |
Immobilization of biologically active proteins with a polypeptide azide |
October 12, 1976 |
| Immobilized biologically active proteins such as enzymes having high activity and stability are prepared by covalent bonding of the biologically active protein to an azide derivative of a polypeptide such as polymethylglutamate of which at least one carboxyl group in a side chain is |
| 3984417 |
Method of producing active amino acid esters |
October 5, 1976 |
| Amino acids having masked amino groups react with amino acids having masked carboxyl groups to form peptide derivatives in good yields if the reaction medium contains an isonitrile. Isonitriles also are effective in causing condensation of amino acids having masked amino groups with comp |
| 3983215 |
Process for preparing NaOH.3.5 H.sub.2 O crystals |
September 28, 1976 |
| NaOH.3.5 H.sub.2 O crystals are prepared by cooling a slurry of 32 to 34% aqueous NaOH solution containing NaOH.3.5 H.sub.2 O seed crystals to below the temperature for saturating the aqueous NaOH solution with respect to NaOH.3.5 H.sub.2 O and separating the precipitated crystals. |
| 3983214 |
Fungicidal compositions and method for protecting plants by the use thereof |
September 28, 1976 |
| Fungicidal compositions for agricultural and horticultural use which contain as an active ingredient one or more compounds selected from the group consisting of tartaric acid, oxalic acid, fumaric acid, citric acid, alkali metal salts of these organic acids, ferric citrate, ferric lactat |
| 3983085 |
Stabilized halogen-containing resin compositions |
September 28, 1976 |
| Thermally stabilized compositions of halogen-containing resins may be obtained by addition to the resin of a stabilizing agent of N.sup..omega.-higher alkyl or higher aliphatic acyl basic amino acid chelates of divalent metals or a mixture of or precursory ingredients thereof which i |
| 3974030 |
Process for producing yeast cells |
August 10, 1976 |
| Certain yeasts are capable of growing in a culture medium containing soybean whey as the main carbon source. The yeast cells have a high protein content, and they are suitable for feed food, and so on. |
