| Patent Number |
Title Of Patent |
Date Issued |
| 5036052 |
Amino acid nutrient compositions |
July 30, 1991 |
| There are herein disclosed stablized and/or dense L-amino acid nutrient compositions, i.e., amino acid infusion solutions, which contain at least one oligopeptide having at least one residue of L-Tryptophan, L-Tyrosine, L-Leucine, L-Isoleucine and L-Valine. |
| 5036004 |
Process for producing L-serine |
July 30, 1991 |
| A process for producing L-serine by the combination of chemical synthesis and enzyme chemical synthesis is disclosed. In this process L-serine is biochemically produced from 2-oxo-axazolidine-4-carboxylic acid or a salt thereof. |
| 5034318 |
Method for producing L-tryptophan by fermentation |
July 23, 1991 |
| A method for producing L-tryptophan comprising culturing coryneform glutamic acid-producing bacteria transformed with an expression vector capable of replicating and expressing an operably linked anthranilic acid phosphoribosyl transferase gene isolated from a brevibacterium glutamic |
| 5033287 |
Method for inspecting a sealing property of a plastic container |
July 23, 1991 |
| A method for inspecting a sealing property of a plastic container having contents. The container has a lid which is deflectable under a negative pressure developed in the container. The contents are charged in to the container so that a negative pressure is developed under a normal t |
| 5032675 |
Process for the production of glutamine derivatives |
July 16, 1991 |
| Improved methods for synthesizing glutamine-containing peptides, involving an active ester method between a protected, C-terminal activated amino acid or a protected, C-terminal activated peptide, and unprotected glutamine in the presence of a weak base, are disclosed. |
| 5028718 |
Amino acid derivatives, their production and use in preparing carbapenem and carbapenam compound |
July 2, 1991 |
| Novel amino acid derivatives of the formula ##STR1## wherein R.sup.1 is a protecting group removable under reducing or acid conditions, and R.sup.2 and R.sup.5 are hydrogen or carboxylic protecting groups, are useful as intermediates in preparing stereospecific carbapenam/carbape |
| 5026842 |
Process for preparing cephalosporin compounds |
June 25, 1991 |
| Reaction of a 7-aminocephalosporanic acid with a carboxylic acid in the presence of a dehydration condensing agent and an acid or acid complex provides the corresponding amide in high yield and high purity. |
| 5023079 |
Heptaene V-28-3 antibiotic derivative |
June 11, 1991 |
| An antimycotic agent having a high degree of antimicrobial activity towards Eumycetes and with a level of toxicity lower than that of heptaene antibiotic V-28-3 is disclosed. This compound is a methyl ester derivative of heptaene antibiotic V-28-3. |
| 5017481 |
Coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by |
May 21, 1991 |
| A brevibacterium containing a recombinant DNA molecule constructed by operatively connecting a gene coding for shikimate kinase isolated from Brevibacterium lactofermentum to a plasmid vector capable of replicating in the Brevibacterium is disclosed along with methods of preparing this |
| 5017364 |
Paste-like dentifrice composition |
May 21, 1991 |
| Herein is disclosed a paste-like dentifrice composition containing, as the foaming agent, from 0.1 to 5.0% by weight of highly pure N-long-chain acylglutamate which contains not more than 1.0% by weight of higher fatty acid(s), either in the free form or in the salt form. |
| 5015386 |
Method for separation of electrolytes, and method for ion exchange of electrolytes with counter- |
May 14, 1991 |
| A method for separating electrolytes which have different charges of the same sign or of carrying out ion exchange of electrolytes with counterions, which comprises causing the electrolytes (anion or cation) to pass through a positively or negatively charged loose reverse-osmotic mem |
| 5013830 |
Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation o |
May 7, 1991 |
| There is disclosed a compound having a double chain which is composed of an RNA (+chain) and a complementary DNA (-chain), wherein a portion of the DNA (-chain) has been replaced by an RNA or a derivative thereof, and wherein, when the compound is subjected to the action of an enzyme hav |
| 5000945 |
Method of stabilizing a UVB absorbing compound, a stabilized UV absorber, and a cosmetic composi |
March 19, 1991 |
| A process for stabilizing a specific UVB absorbing compound which comprises adding to said UVB absorbing compound at least one specific UVA absorbing compound in an amount of 0.1-10 parts by weight based on 1 part by weight of UVB absorbing compound is disclosed and also a cosmetic compo |
| 4997754 |
Process for recovering L-amino acids from fermentation liquors containing them |
March 5, 1991 |
| A process for recovering a high-purity L-amino acid from a fermentation liquor obtained by fermentation or an enzymic method, which comprises removing the impurities contained in said fermentation liquor by passing said fermentation liquor through an ultrafilter membrane and then through |
| 4996286 |
Trihydrazide latent curing agent for epoxy resins |
February 26, 1991 |
| A latent curing agent for epoxy resin, characterized in that the latent curing agent is the hydrazides of the formula (I);The present curing agent is useful in formulating storable, one-package, heat-curable epoxy resin-based compositions. |
| 4996067 |
Feed additive for ruminants |
February 26, 1991 |
| A feed additive for ruminants, which comprises cores containing an acid salt of a basic amino acid, and a first coating layer and a second coating layer coated sequentially on the surface of each core, wherein said first coating layer contains at least one first coating agent selected fr |
| 4994605 |
Method of separating alpha-L-aspartyl-L-phenylalanine methyl ester through crystallization |
February 19, 1991 |
| A method for crystallizing alpha-L-aspartyl-L-phenylalanine methyl ester (APM) is disclosed. The APM is crystallized from a C.sub.1 -C.sub.3 -alcohol/water solution (30-80:70-20 (v/v)). The ester crystallized by (i) concentrating the solution, (ii) cooling the solution, (iii) adjusting t |
| 4992129 |
Transfer printing method |
February 12, 1991 |
| A method for thermal transfer printing by heating a transfer sheet having a printing ink layer formed on a base sheet with a hot roll, wherein the base sheet comprises biaxially stretched plastic film, and, at the same time, pressing with the hot roll the transfer sheet against a substra |
| 4987123 |
Compositions useful for the treatment and/or prevention of hepatic disorders, and their pharmace |
January 22, 1991 |
| A composition, comprising L-alanine or a salt thereof, L-glutamine or a salt thereof, and an oligopeptide containing either a L-alanine residue or a L-glutamine residue, or both, is disclosed. A composition made up of (i) L-alanine or a salt thereof, (ii) L-glutamine or a salt thereof, a |
| 4986995 |
Process for producing retort boiled rice |
January 22, 1991 |
| A process for producing retort boiled rice by charging raw rice and water into a container, adjusting the quantity of oxygen in the head space of the container to from 4-12 ml/100 g of raw rice, sealing the container and then boiling and sterilizing the rice. |
| 4985237 |
Benzylidene compounds, cosmetic compositions containing the same and ultraviolet absorber compri |
January 15, 1991 |
| Disclosed herein are benzylidene compounds represented by the formula (I): ##STR1## wherein A represents ##STR2## (wherein B represents hydrogen atom or an acetyl group, W represents hydrogen atom or --CH.sub.2 --CH.sub.2 --CO--O--R, X.sup.1, X.sup.2 and X.sup.3 represent ind |
| 4980285 |
Method for producing L-amino acids |
December 25, 1990 |
| A method for producing an L-amino acid, which comprises inserting a gene which codes for an enzyme which is utilized on the route of biosynthesis of an L-amino acid product into one of at least two plasmid vectors which have compatible replicating origins different from each other, inser |
| 4971993 |
Dipeptide derivatives and antihypertensive drugs containing them |
November 20, 1990 |
| There are disclosed dipeptide derivatives represented by the general formula: ##STR1## wherein R.sup.1 is a radical selected from the group consisting of alkyl, aralkyl and aryl groups optionally containing one or more substituent groups, R.sup.2 is a radical selected from the gr |
| 4970148 |
Method of producing 2',3'-dideoxyinosine |
November 13, 1990 |
| A method of producing dideoxyinosine involving contacting as a substrate 2',3'-dideoxyadenosine with a microorganism which is capable of converting the substrate into 2',3'-dideoxyinosine. |
| 4968609 |
Coryneform bacteria carrying recombinant DNA and a process for producing aromatic amino acids us |
November 6, 1990 |
| The present invention relates to a process for producing an aromatic amino acid which comprises culturing a Coryneform bacterium carrying a recombinant DNA constructed by connecting (1) a gene capable of being expressed in a Coryneform bacterial cell and coding for 3-deoxy-D-arabino- |
| 4968606 |
Methods for producing ribose-1-phosphoric acid and ribavirin |
November 6, 1990 |
| The present invention relates to methods for producing ribavirin utilizing microorganisms and a method for producing ribose-1-phosphoric acid which is a precursor of ribavirin. The methods involve contacting certain microorganisms with orotidine, orotidic acid, or salts thereof, and |
| 4962193 |
Process for purifying 2',3'-dideoxynucleosides |
October 9, 1990 |
| A biological process for producing a 2',3'-dideoxynucleoside from 2',3'-dideoxyuridine is disclosed. the 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent. |
| 4956191 |
Method of preparing a carbonated beverage containing aspartame |
September 11, 1990 |
| A carbonated beverage is produced which comprises a low-calorie sweetener such as aspartame, and a cold water-soluble natural gum, particularly gum arabic. It is a low calorie beverage which possesses excellent palatability and a reduced tendency to cause dental caries. |
| 4946781 |
Recombinant DNA, bacteria carrying said recombinant DNA and a process for producing L-threonine |
August 7, 1990 |
| A recombinant DNA molecule comprising a plasmid vector having operationally inserted therein a gene coding for homoserine kinase is disclosed along with bacteria containing this recombinant DNA molecule and methods of using these bacteria to produce amino acids in large quantities. |
| 4943652 |
Process for asymmetrically reducing carbonyl compounds |
July 24, 1990 |
| There is disclosed a process for asymmetrically reducing a carbonyl compound, which comprises reducing the carbonyl compound by the use of a reducing agent comprising (i) an optically active tartaric acid or ester thereof and (ii) a metal borohydride, thereby producing an optically a |
| 4942255 |
Method for producing .alpha.-aspartylphenylalanine derivatives |
July 17, 1990 |
| A method for producing an .alpha.-aspartylphenylalanine derivative represented by formula (2), which comprises reacting a .beta.-aspartylphenylalanine derivative represented by formula (1): ##STR1## with a basic compound in an alcohol solvent in the presence of a hydroxide, sulfa |
| 4940332 |
Fluorescent analysis apparatus |
July 10, 1990 |
| An apparatus for measuring the presence of microorganisms using fluorescent substances. A number of samples are measured continuously by enclosing the entire reacting and measurement sections within a thermostatically controlled enclosure. A number of samples are placed in containers wit |
| 4911861 |
Polyphenyl-based ester compounds and liquid crystal compositions containing same |
March 27, 1990 |
| Polyphenyl-based liquid crystal compounds represented by the following general formula (1) and liquid crystal composition containing the same: ##STR1## wherein R.sup.1 represents a straight or branched C.sub.1-18 alkyl group, haloalkyl group, aralkyl group or haloaralkyl group with o |
| 4904802 |
Imides |
February 27, 1990 |
| An imide of the formula: ##STR1## where R.sub.1 is hydrogen or C.sub.1-4 alkyl. |
| 4897507 |
Method for producing .alpha.-L-aspartyl-L-phenylalanine derivatives |
January 30, 1990 |
| A method for producing .alpha.-L-aspartyl-L-phenylalanine dimethyl ester, which comprises reacting 3-benzyl-6-carboxymethyl-2,5-diketopiperazine or methyl ester thereof in a methanolic solvent substantially free from water in the presence of a strong acid. |
| 4897460 |
Curing agent for epoxy resins from a mixture of a substituted urea and a dicarboxylic acid |
January 30, 1990 |
| The present invention relates to an one-packed type epoxy resin composition. An object of the present invention is to provide epoxy resin composition which have good compatibility with epoxy resin, exhibit excellent stability during storage and heat stability, can be used at about ro |
| 4892676 |
Phenyl pyrimidine compound and liquid crystalline composition |
January 9, 1990 |
| A phenyl pyrimidine compound of this invention represented by the following formula (I) forms a smectic C phase and is useful for a constituent of a ferroelectric liquid crystal composition.wherein Ph represents 1,4-phenylene group, Py represents 2,5-pyrimidine, R.sub.1 and R.sub.2 repre |
| 4885245 |
Process for producing L-tryptophan |
December 5, 1989 |
| A process for producing L-tryptophan in which a suitable substrate such as a carbohydrate, indole or anthranilic acid is contacted with Coryneform bacteria, where the Coryneform bacteria bear recombinant DNA constructed by connecting a gene coding for tryptophan synthetase with a plasmid |
| 4880561 |
Optically active compound and liquid crystalline composition |
November 14, 1989 |
| Disclosed is an optically active cyclopropane compound represented by the formula (1): ##STR1## wherein R is an alkyl or cycloalkyl group, n is 0 or 1, Y.sup.4 is --CO.sub.2 CH.sub.2 --, --OCO-- or --OCH.sub.2 --, Y.sup.1, Y.sup.2 and Y.sup.3 independently represent --CO.sub.2 -- |
| 4876383 |
Amino acid derivatives, their production and use in preparing carbapenem and carbapenam compound |
October 24, 1989 |
| Novel amino acid derivatives of the formula ##STR1## wherein R.sup.1 is a protecting group removable under reducing or acid conditions, and R.sup.2 and R.sup.5 are hydrogen or carboxylic protecting groups, are useful as intermediates in preparing stereospecific carbapenam/carbape |
| 4874542 |
Phenyl-pyrimidine liquid crystal compounds and liquid crystal compositions containing the same |
October 17, 1989 |
| A phenyl-pyrimidine liquid crystal compound represented by the formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each represent an alkyl group having 1 to 18 carbon atoms, and X and Y each represent one of a single bond, --O--, --OCO--, --COO-- and --OCOO--, |
| 4872590 |
Resin coated can with folded seam |
October 10, 1989 |
| A plastic can is formed of a body member including a content protecting layer which is a tubular body formed by folding back and outward one side edge of a laminated film, bonding the folded parts such that air bubbles are not entrapped thereunder, overlapping the other side edge of the |
| 4871558 |
Oil or fat coated substance and method of making the same |
October 3, 1989 |
| The invention relates to an oil or fat coated substance comprising a core material coated with a mixture comprising a solid fat and an edible wax. |
| 4859701 |
Azulene derivatives and pharmaceutical compositions containing them |
August 22, 1989 |
| Azulene derivatives of the following formula ##STR1## wherein R.sup.1 stands for an alkyl group of 1 to 3 carbon atoms, R.sup.2 stands for an alkyl group of 1 to 3 carbon atoms, and R.sup.3 is at the 5- or 6- position and stands for an alkyl group of 1 to 6 carbon atoms, an aryl |
| 4849535 |
Production of cyclopentenylheptanoic acid derivatives |
July 18, 1989 |
| Cyclopentenylheptanoic acid derivatives having the formula: ##STR1## wherein R is hydrogen or C.sub.1 to C.sub.4 alkyl and --(A)-- is: ##STR2## wherein M is hydrogen or triorganosilyl group, are prepared by reacting a compound having the formula: ##STR3## ps wherein X is |
| 4849238 |
Foodstuffs having improved taste quality |
July 18, 1989 |
| A foodstuff having improved taste quality comprising a taste-improving amount of a pepper extract, a piperine-containing fraction of pepper or one or more piperines. |
| 4843093 |
Butyrolactone derivatives, process for production thereof and use therefor |
June 27, 1989 |
| Butyrolactone derivatives having the formula ##STR1## wherein R is a C.sub.4 -C.sub.10 alkyl group, which have an appetite-regulating effect, a process for their production, and compositions containing them, are disclosed. |
| 4831182 |
Biphenyl-based diester compounds and liquid crystal compositions containing same |
May 16, 1989 |
| A liquid crystal compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 represent C.sub.1-18 alkyl group, alkyl halide group or aralkyl halide, R.sup.1 may be the same as or different from R.sup.2, X is selected from --COOCH.sub.2 -- or --OCO--. |
| 4830867 |
Process for producing pasta sheets |
May 16, 1989 |
| A process for producing pasta sheets which comprises adding water to a starching flour comprising raw starch: .alpha.-starch in a weight ratio of about 95:5 to about 35:65, kneading the mixture and thereafter extending the mixture. Products having excellent transparency and machinability |
| 4824994 |
Method for production of N-protected-alpha-L-aspartyl-L-phenylalanine methyl ester |
April 25, 1989 |
| A method for the production of N-carbobenzoxy-.alpha.-L-aspartyl-L-phenylalanine methyl ester characterized by the reaction of L-phenylalanine methyl ester with fine N-carbobenzoxy-L-aspartic anhydride crystals, is disclosed. |
