| Patent Number |
Title Of Patent |
Date Issued |
| 5231105 |
Ethylamine derivatives and antihypertensives containing the same |
July 27, 1993 |
| An ethylamine derivative of formula (I): ##STR1## wherein A represents a carbon atom or a nitrogen atom;B represents a substituted or unsubstituted aralkyl or aryl group;C represents hydrogen, alkyl, aralkyl, or aryl, each of which may optionally be substituted orC may optionally be bond |
| 5229400 |
Piperidine compounds and their use as antiarrhythmic agents |
July 20, 1993 |
| A piperidine derivative of general formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein ##STR2## is any of several specified aromatic-containing groups; X is selected from one of several hetero atom-containing groups or C.sub.2 alkylene or a cyano-c |
| 5227166 |
Feed additive for ruminants |
July 13, 1993 |
| The present invention relates to a biologically active substance that is stable in the rumen of ruminants and released in the abomasum and its subsequent digestive tract. The biologically active substance has the additional properties of being digested and absorbed with good efficiency. |
| 5225587 |
Method of producing .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride |
July 6, 1993 |
| A method of purifying .alpha.-L-aspartyl-L-phenylalanine methyl ester as a hydrochloride salt thereof which comprises:i) contacting a mixture of .alpha.-L-aspartyl-L-phenylanaline methyl ester and .beta.-L-aspartyl-L-phenylalanine methyl ester with an aqueous medium containing (a) hydrog |
| 5219744 |
Process for modifying fats and oils |
June 15, 1993 |
| A process for modifying fats and oils which comprises applying partial glyceride lipase to fats and oils containing partial glycerides and fatty acids to synthesize triglycerides from the partial glycerides by esterification.The lipase is preferably an immobilized lipase and this process |
| 5216172 |
1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resista |
June 1, 1993 |
| Agents against drug-resistant tumor cells comprising a 1,4-dihydropyridine derivative represented by the following formula (I): ##STR1## wherein R.sup.1 is an aryl group which may be substituted;R.sup.2 and R.sup.3, which may be the same or different, each is a member selected from t |
| 5210073 |
Method for treating cancer therapy radiation damage or arteriosclerosis using human ADF |
May 11, 1993 |
| A composition and method for the treatment of inflammation, rheumatism, autoimmune disease, ischemic damage of organs, drug toxicity and arteriosclerosis comprising human ADF is disclosed. |
| 5204459 |
Process for preparing carbapenem compounds |
April 20, 1993 |
| Novel amino acid derivatives of the formula ##STR1## wherein R.sup.1 is a protecting group removable under reducing or acid conditions, and R.sup.2 and R.sup.5 are hydrogen or carboxylic protecting groups, are useful as intermediates in preparing stereospecific carbapenam/carbape |
| 5196326 |
Method for concurrent fermentation of basic amino acid and acidic amino acid |
March 23, 1993 |
| A basic L-amino acid and an acidic L-amino acid may be concurrently produced by either culturing a basic L-amino acid-producing bacteria under conditions for producing an acidic L-amino acid or mix-culturing a basic L-amino acid-producing bacteria and an acidic L-amino acid-producing |
| 5194625 |
Process for production of alpha-keto acid/amino acid salt compounds |
March 16, 1993 |
| A compound of the formula:wherein A represents an amino acid, N represents an .alpha.-keto acid, S represents a lower alcohol or acetone; and x ranges from 0.1 to 3. |
| 5189145 |
Flower-inducing substances and a method for production thereof |
February 23, 1993 |
| Flower-inducing substances containing protein or peptide materials and obtained by extraction of plant materials with water. |
| 5188949 |
Method for producing L-threonine by fermentation |
February 23, 1993 |
| A method for producing L-threonine by fermentation which comprises culturing in a culture medium a microorganism of the genus Brevibacterium or Corynebacterium which is resistant to mycophenolic acid and is capable of producing L-threonine, accumulating L-threonine in the medium, and the |
| 5188948 |
Process for producing L-valine by fermentation |
February 23, 1993 |
| A process for producing L-valine by fermentation which comprises culturing in a liquid culture medium an L-valine producing microorganism which belongs to the genus Brevibacterium or Corynebacterium and which is resistant to a polyketide, and then recovering L-valine accumulated in s |
| 5188947 |
Process and microorganism for producing L-ornithine by Corynebacterium, Brevibacterium, or Athro |
February 23, 1993 |
| A process for producing L-ornithine by fermentation which comprises culturing a L-ornithine-producing microorganism is disclosed. The microorganism used belongs to the genus Brevibacterium, Corynebacterium, or Arthrobacter, has auxotrophy for arginine and/or citrulline, and has resis |
| 5186931 |
Composition and method for supporting bone marrow transplantation |
February 16, 1993 |
| A composition and a method for supporting bone marrow transplantation are disclosed. The composition comprises a therapeutically acceptable amount of human B cell differentiation factor, or its biological equivalent, optionally in combination with an auxiliary agent selected from IL-1, |
| 5179010 |
Fermentation process for producing L-lysine |
January 12, 1993 |
| A fermentative process for producing L-lysine is disclosed. The process is based on growing in a culture medium a mutant strain of the genus Brevibacterium or Corynebacterium (1) capable of producing L-lysine, and (2) having an intensified superoxide dismutase activity. |
| 5179009 |
Process for producing L-aspartyl-L-phenylalanine and its diketopiperazine |
January 12, 1993 |
| The present invention is directed to a process for producing L-aspartyl-L-phenylalanine and/or L-aspartyl-L-phenylalanine diketopiperazine comprising contacting and reacting a culture, cell or a cell-treated product of a microorganism capable of hydrolyzing DKP into AP or capable of |
| 5177264 |
Process for preparing an N-substituted (meth)acrylamide derivative |
January 5, 1993 |
| An N-substituted dialkylacetal (meth)acrylamide of formula II: ##STR1## wherein n represents 3 or 4; R.sub.1 represents hydrogen or methyl; and R.sub.2 represents an alkyl of 1 to 3 carbon atoms is prepared by thermally decomposing an aminoacetal derivative represented by Formula I: |
| 5177013 |
Preparation of an immobilized lipase having a low water content without drying |
January 5, 1993 |
| Lipase is absorbed on a carrier to provide an immobilized lipase preparation containing 0.5 to 8% water by a process that does not require drying. The process is carried out by providing a solution or dispersion of lipase in a liquid solvent, mixing the solution or dispersion of lipase |
| 5175107 |
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine |
December 29, 1992 |
| A bacterial strain of Escherichia coli BKIIM B-3996, a producere of L-threonine, containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antibiotics Research Institute under Reg. No. 1867. |
| 5169671 |
Food containing fructose polymer |
December 8, 1992 |
| There is provided a food and drink having a reduced oil, fat, or sugar content yet retaining good gelation properties and good organoleptic properties, etc. A part of or the whole of gelation materials, low calorie sugars and/or oils and fats is/are replaced with polyfructan. |
| 5166064 |
Immobilized of lipase on a cation exchange resin |
November 24, 1992 |
| An immobilized lipase is prepared by adsorbing lipase on a carrier that is capable of retaining 3% or more by weight of water after drying under a reduced pressure of from 0.01 to 1.0 Torr at 70.degree. C. for 60 hours. A cation exchange resin is a preferred carrier and a weakly acidic c |
| 5164307 |
Process for producing L-amino acids by fermentation |
November 17, 1992 |
| A process is provided for producing an L-amino acid, which entails culturing bacteria producing the L-amino acid in a medium containing cane molasses, sucrose or glucose as a main carbon source and containing at least one substance selected from the group consisting of N-methylglycine, |
| 5164306 |
Process for producing 5'-inosinic acid by fermentation |
November 17, 1992 |
| A process for producing 5'-inosinic acid by culturing 5'-inosinic acid-producing bacteria in a medium containing inosine, and cane molasses, sucrose or glucose as the main carbon source and containing at least one of L-methylglycine, N,N-dimethylglycine, N,N,N-trimethylglycine and (2 |
| 5160621 |
Method for treatment of waste water by activated sludge process |
November 3, 1992 |
| A method for treatment of waste water by an activated sludge process wherein the aeration tank system is composed of three tanks: a first tank, a second tank and a third tank, in which sludge microorganisms adsorb the organic substances in the waste water to be treated and a part of them |
| 5156956 |
Transgultaminase |
October 20, 1992 |
| A transglutaminase catalyzing an acyl transfer reaction of a .gamma.-carboxyamide group of a glutamine residue in a peptide or protein chain in the absence of Ca.sup.2+. |
| 5153340 |
Oil-soluble N-long chained acyl acidic amino acid ester, mixture thereof and perfuming cosmetics |
October 6, 1992 |
| Herein are disclosed (1) an oil-soluble N-long chained acyl acidic amino acid mono- or di-ester having at least one sterol ester in the molecule, which is a novel compound of excellent emulsifying and hydrating performances, (2) an oily composition consisting of or comprising a mixtu |
| 5153013 |
Method for preparing fat-and-oil-coated sweetener compositions and compositions so prepared |
October 6, 1992 |
| By adding lecithin and/or a surfactant having an HLB value of not greater than 6 either before or during the addition of a peptide sweetener to a heated and melted fat or oil, the problems of viscosity increase and gelation may be overcome even when the sweetener is added in large amount |
| 5149640 |
Method for producing galactose transfer products |
September 22, 1992 |
| A galactose transfer product is prepared by a process of allowing a microorganism capable of producing a galactose transfer product of the formula: (Gal).sub.n --R, wherein Gal represents a galactose residue, n represents an integer of 1 to 4 and R represents a galactose receptor to |
| 5142079 |
Fluorinated carbon chain-containing aluminum surface modifier |
August 25, 1992 |
| The novel fluorinated carbon chain-containing aluminum compounds which are capable of imparting an SP value of desired level to inorganic materials and hence can be used as surface modifiers for improving the affinity between inorganic materials and fluororesins, fluorine-containing pain |
| 5128478 |
Oxazoline-carboxylic acid derivatives and method for the preparation thereof |
July 7, 1992 |
| Optically active oxazoline-carboxylic acid derivatives of the formula: ##STR1## wherein R.sup.1 represents a hydrogen atom, an alkyl group having 1 to 20 carbon atoms, an alkykl group which is substituted and has 1 to 20 carbon atoms, a cycloalkyl group, a cycloalkyl group which is s |
| 5126325 |
Method for treating thrombocytopenia |
June 30, 1992 |
| Thrombocytopenia is treated by administering to a subject a therapeutic amount of human B cell differentiation factor or its biological equivalent. |
| 5118840 |
Method of crystallizing phenylalanine |
June 2, 1992 |
| A method of crystallizing phenylalanine in the form of .alpha.-crystals at a temperature below .alpha..fwdarw..beta. transition temperature comprises:forming an aqueous solution of phenylalanine at a temperature above the .alpha..fwdarw..beta. transition temperature, the aqueous solution |
| 5118831 |
Amino acid derivatives, their production and use in preparing carbapenem and carbapenam compound |
June 2, 1992 |
| Novel amino acid derivatives of the formula ##STR1## wherein R.sup.1 is a protecting group removable under reducing or acid conditions, and R.sup.2 and R.sup.5 are hydrogen or carboxylic protecting groups, are useful as intermediates in preparing stereospecific carbapenam/carbape |
| 5118815 |
Method for crystallization of amino acids |
June 2, 1992 |
| A method for crystallization of an amino acid characterized by allowing a surfactant and/or an alcohol to exist upon crystallization. |
| 5106962 |
Process for preparing 2',3'-dideoxy nucleoside derivatives |
April 21, 1992 |
| A process for preparing 2',3'-didehydro-2',3'-dideoxynucleoside derivatives (III) ##STR1## by reacting a compound (I) ##STR2## with a viologen (N,N'-dialkyl-4,4'-bipyridinium salt) is disclosed. In the formulae R.sup.1 is C.sub.1-12 acyl or sulfonyl, R.sup.2 is hydrogen, |
| 5104855 |
Demethylallosamidin and a process for production thereof |
April 14, 1992 |
| An antifungal compound, demethylallosamidin, represented by the formula: ##STR1## is disclosed. Methods of production and antifungal compositions comprising demethylallosamidin are also provided. |
| 5101011 |
Aligning agent for liquid crystals comprising poly alpha-amino acid having no optical activity |
March 31, 1992 |
| An aligning agent for liquid crystals containing a polyamino acid having no optical activity. |
| 5100579 |
Polyphenyl-based ester compounds and liquid crystal compositions containing same |
March 31, 1992 |
| Polyphenyl-based liquid crystal compounds represented by the following general formula (1) and liquid crystal composition containing the same: ##STR1## wherein R.sup.1 represents a straight or branched C.sub.1-18 alkyl group, haloalkyl group, aralkyl group or haloaralkyl group with o |
| 5087729 |
Benzylidene compounds, cosmetic compositions containing the same and ultraviolet absorber compri |
February 11, 1992 |
| Disclosed herein are benzylidene compounds represented by the formula (I): ##STR1## wherein A represents ##STR2## (wherein B represents hydrogen atom or an acetyl group, W represents hydrogen atom or --CH.sub.2 --CH.sub.2 --CO--O--R, X.sup.1, X.sup.2 and X.sup.3 represent ind |
| 5087517 |
Composite sheet used for reproducible electrostatic image display or record |
February 11, 1992 |
| Disclosed herein is a composite sheet for reproducible electrostatic image display or record comprising,a semiconductor film containing an electroconductive filler and having a uniform surface resistivity of a range of 10.sup.3 to 10.sup.10 106 /.quadrature. anda highly dielectric film h |
| 5077207 |
Process for the production of L-threonine by fermentation |
December 31, 1991 |
| A process for the production of L-threonine, comprising cultivating a mutant bacterial species belonging to the genus Brevibacterium from which dihydrodipicolinate synthase has been deleted or removed in a liquid medium; accumulating the L-threonine as a product of cultivation; and h |
| 5070191 |
Demethylallosamidin and a process for production thereof |
December 3, 1991 |
| An antifungal compound, demethylallosamidin, represented by the formula: ##STR1## is disclosed. Methods of production and antifungal compositions comprising demethylallosamidin are also provided. |
| 5069707 |
Method for regulating the flowering of plants and flowering regulators of plants |
December 3, 1991 |
| The flowering of plants can be regulated by treating the plants with a protease inhibitor, such as, e.g., elastinal, bestatin, diisopropylfluorophosphoric acid (DFP), and CTAH. The protease inhibitor may be applied in the form of a composition, and the method is useful to control the |
| 5066590 |
Superoxide dismutase combined with a poly(alkylene oxide) |
November 19, 1991 |
| Superoxide dismutase is chemically modified with poly(alkylene oxide), the modified superoxide dismutase having a molecular structure in which both ends of a poly(alkylene oxide) molecule are attached to superoxide dismutase. The modified superoxide dismutase can be used to remove toxic |
| 5064057 |
Support for anastomosing or connecting living organs |
November 12, 1991 |
| Disclosed herein is a support for anastomosing or connecting living organs in a living body which comprises a material selected from the group consisting of monosaccharide, oligosaccharide, polysaccharide, a mixture thereof, and polyvinyl pyrrolidone.The support provided according to the |
| 5055310 |
Process of preparing shelf-stable "tofu" at normal temperature for long term |
October 8, 1991 |
| Shelf stable soybean curd which is stable for extended periods of time is prepared by reacting soy milk with a solidifying agent and a transglutaminase, which is not dependent on Ca.sup.+2 ions and which is capable of catalyzing the acyl rearrangement of .gamma.-carboxyamide in the g |
| 5045369 |
Plastic container and method for manufacturing the same |
September 3, 1991 |
| A container substantially made of plastic materials and having a gas barrier property. The container has a wall including a laminated sheet which comprises an inner layer and an outer layer both made of a thermoplastic material and an intermediate barrier layer between the inner and |
| 5041607 |
Process for crystallizing L-alpha-aspartyl-L-phenyl-alanine methyl |
August 20, 1991 |
| A crystalline L-alpha-aspartyl-L-phenyl-alanine methyl ester product is disclosed. The product is obtained by crystallizing the ester from an aqueous solution, by cooling. The initial concentration of ester in the aqueous solution used provides at least 10 grams of precipitated solid |
| 5041579 |
Platinum complexes and uses therewith |
August 20, 1991 |
| Platinum complexes of cis-diaminocyclohexanol or cis-diaminocyclohexane, with the exclusion of platinum complexes of 2-deoxystreptamine, having high anti-tumor activity, low toxicity, water-solubility and exhibiting no cross-resistance to cis-platin. |
