| Patent Number |
Title Of Patent |
Date Issued |
| 6147148 |
Thermal-aging resistant thermoplastic resin composition comprising a dibasic acid erythritol est |
November 14, 2000 |
| A thermoplastic resin composition comprising a thermoplastic resin, a dibasic acid erythritol ester, a filler and optionally an antioxidant. The dibasic acid erythritol ester, having a degree of esterification of not more than 50%, is added in an amount less than 1 part by weight, per 10 |
| 6146878 |
Tyrosine repressor gene of a bacterium belonging to the genus Erwinia |
November 14, 2000 |
| Using as a host Escherichia coli which expresses lactose operon under the control of the promoter/enhancer of tyrosine phenol lyase gene derived from Erwinia herbicola, a DNA fragment coding for tyrosine repressor (tyrR) having an amino acid sequence depicted in SEQ ID NO: 2 in Sequence |
| 6143695 |
Plant-root growth promoting agent |
November 7, 2000 |
| Herein are disclosed, a plant-root growth promoting agent, which comprises inosine as the effective ingredient, as well as a method for promoting plant root growth, which comprise applying such plant-root growth promoting agent to the soil or, in the case of hydroponics, to the hydro |
| 6143323 |
Tablet composition |
November 7, 2000 |
| A tablet composition containing N-(trans-4-isopropylcydohexanecarbonyl)-D-phenylalanine and low substituted hydroxypropylcellulose is disclosed. This tablet composition is rapidly disintegrated in the stomach after the administration and absorbed without being influenced by meals to |
| 6133377 |
Compostion of epoxy resin, phenol-triazine-aldehyde condensate and rubber |
October 17, 2000 |
| The present invention provides an epoxy resin composition comprising: (a) an epoxy resin having two or more epoxy groups in each molecule; (b) a phenolic resin composition comprising a condensation product of: (i) a phenol; (ii) a compound having a triazine ring; and (iii) an aldehyde, t |
| 6132999 |
L-threonine-producing microbacteria and a method for the production of L-threonine |
October 17, 2000 |
| The present invention provides a novel microbial strain and a method for effectively producing L-threonine. The novel strain can grow on a medium containing molasses, a much cheaper raw material than sucrose. The exemplary novel strain E. coli BKIIM B-5318 bears the plasmid pPRT614, |
| 6127174 |
Plasmid derived from gluconobacter bacteria and vector |
October 3, 2000 |
| A shuttle vector autonomously replicable in bacteria belonging to the genera Gluconobacter and Escherichia is constructed from an endogenous plasmid of Gluconobacter oxydans IF03171 strain, which has a size of about 5.6 kb, or a part thereof, and a plasmid autonomously replicable in |
| 6124121 |
Method for producing L-leucine |
September 26, 2000 |
| L-leucine is produced by culturing a bacterium belonging to the genus Escherichia, which has an ability to produce L-leucine and is resistant to L-leucine in a culture medium to produce and accumulate L-leucine in the medium, and recovering L-leucine from the medium. |
| 6124023 |
Prepreg for laminate and process for producing printed wiring-board using the same |
September 26, 2000 |
| The problems are to provide a prepreg for laminate which can secure a heat resistance, electrical insulation properties and an adhesion strength of a conductor layer, a printed wiring-board which satisfies a high density and which is excellent in a heat resistance and electrical insulati |
| 6121597 |
Packaging bag for use in a microwave oven |
September 19, 2000 |
| This invention provides a packaging bag for a microwave oven capable of allowing vapor generatetd during microwave heating to escape surely, which comprises a bag body comprising an upper side sheet portion and an underside sheet portion and an upper fin seal portion formed on the upper |
| 6114525 |
Method for purifying nucleic acid derivatives |
September 5, 2000 |
| A pure (-)-9-[1'S, 2'R-bis(hydroxymethyl)cyclopropan-1'-yl]methylguanine is prepared by:suspending or dissolving a mixture comprising (-)-9-[1'S, 2'R-bis(hydroxymethyl)cyclopropan-1'-yl]methylguanine and (7-[1'S,2'R-bis(hydroxymethyl)cyclopropan-1'-yl]methylguanine in an alcohol or a |
| 6110714 |
Process for producing L-glutamic acid by fermentation |
August 29, 2000 |
| An isolated mutant microorganism which belongs to the genus Escherichia, which exhibits valine sensitivity which is indicated by failure to grow in an M9 minimum growth medium containing 50 mg/liter of valine, and which has amplified citrate synthase activity and phosphoenolpyruvate |
| 6106887 |
Process for obtaining a modified cereal flour |
August 22, 2000 |
| A method for modifying cereal flour by treating it with transglutaminase during the process of milling cereal flour, as well as processed foods containing the modified cereal-flour, such as noodles, breads, pastries. |
| 6093846 |
Process for preparing optically active 2-hydroxy-methyl-3-phenylpropionic acid |
July 25, 2000 |
| A process for preparing optically active 2-hydroxymethyl-3-phenylpropionic acid by resolving (RS)-2-hydroxymethyl-3-phenylpropionic acid via crystallization of an optically active amine salt, where the amine is optically active cis-1-amino-2-indanol salt, optically active .alpha.-met |
| 6090937 |
Methods for producing nucleoside derivatives and intermediates therefor |
July 18, 2000 |
| Novel intermediates of nucleoside derivatives, of which the 6-position of the nucleic acid base moiety is substituted with a halogen atom, are produced. Using those novel intermediates, even substrates, of which the 3'-position of the saccharide moiety is deoxylated, can be substituted a |
| 6090597 |
Method of producing L-lysine |
July 18, 2000 |
| A coryneform bacterium in which a DNA coding for a diaminopimelate decarboxylase and a DNA coding for a diaminopimelate dehydrogenase are enhanced is cultivated in a medium to allow L-lysine to be produced and accumulated in a culture, and L-lysine is collected from the culture. |
| 6087526 |
Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester |
July 11, 2000 |
| Provided is an industrially useful process for producing an optically active 2-hydroxy-4-arylbutyric acid or its ester. An optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4- |
| 6087497 |
Process for producing purine derivatives |
July 11, 2000 |
| 9-Substituted purine derivatives of formula (4) ##STR1## are prepared by debenzylating a compound of formula (3): ##STR2## |
| 6084076 |
Method of refolding human activin A |
July 4, 2000 |
| A method for industrially producing human activin A which comprises refolding a modified human activin A produced by a microorganism into natural-form human activin A having a biological activity. This method comprises the steps of: (a) solubilizing the modified human activin A with |
| 6083549 |
Taste-improving agent and a food having improved taste |
July 4, 2000 |
| The bitterness, astringency and persistent sweetness possessed commonly by intense sweeteners may be reduced to afford a lightly sweet aftertaste, by the addition of an amino acid derivative such as N-(1-methyl-4-oxo-2-imidazolin-2-yl)alanine or analogues thereof. |
| 6075045 |
Method of treating paralysis of the extremities caused by cerebral infarction |
June 13, 2000 |
| The administration of a therapeutically effective amount of melatonin is an effective method for treating paralysis of the extremities caused by cerebral infarction. |
| 6072083 |
Method for purifying branched chain amino acids |
June 6, 2000 |
| A method for purifying an amino acid selected from the group consisting of valine, leucine and isoleucine easily in high yield and with high purity using an inexpensive precipitant, comprising allowing p-ethylbenzenesulfonic acid or its water-soluble salt to act on an aqueous solutio |
| 6063408 |
Process for producing chocolate |
May 16, 2000 |
| A process is provided for producing a chocolate having improved stability, and which is effective for preventing blooming, particularly fat blooming, the process involving kneading a chocolate starting material with a transglutaminase to effect reaction of the transglutaminase with the |
| 6060613 |
Process for producing N-long-chain acyl acidic amino acids or salts thereof |
May 9, 2000 |
| Provided is an industrially advantageous process for producing an N-long chain acyl acidic amino acid by condensing an acidic amino acid with a long chain fatty acid halide in water in the presence of an alkali, wherein the reaction is performed in the presence of a polyhydric alcohol. |
| 6060289 |
Modified bacterial cellulose |
May 9, 2000 |
| This invention provides a bacterial cellulose comprising ribbon-shaped microfibrils having a thickness of 10 to 100 nm and a width of 160 to 1000 nm or a bacterial cellulose comprising ribbon-shaped microfibrils having a thickness of 10 to 100 nm and a width of 50 to 70 nm. The former ba |
| 6040160 |
Method of producing L-lysine by fermentation |
March 21, 2000 |
| A bacterium belonging to the genus Escherichia, which is transformed by introducing, into its cells, a DNA coding for a dihydrodipicolinate synthase originating from a bacterium belonging to the genus Escherichia having mutation to desensitize feedback inhibition by L-lysine and a DNA |
| 6039879 |
Method for separating and recovering objective component |
March 21, 2000 |
| A method for separating and recovering an objective component from a crude liquid by a membrane in a semi-batch system, including the steps of: at least two stages of adding a washing liquid to the crude liquid stored in a container and mixing the washing liquid with the crude liquid to |
| 6037154 |
Method of producing L-serine by fermentation |
March 14, 2000 |
| L-serine is produced by cultivating in a medium a coryneform bacterium having L-serine productivity in which an activity of at least one of phosphoserine phosphatase and phosphoserine transaminase is enhanced, preferably, further having introduced therein a gene coding for D-3-phosop |
| 6031121 |
Method for producing optically active phenylpropionic acid derivative |
February 29, 2000 |
| Optically active N-(S-2-acetylthiomethyl-1-oxo-3-phenylpropyl)-glycine benzyl ester useful as an enkephalin inhibitory agent or ACE inhibitory agent can be produced at low cost in an industrial manner, by a method comprising subjecting optically active 2-hydroxymethyl-3-phenylpropionic |
| 6030821 |
Stabilized transglutaminase and enzyme preparation containing the same |
February 29, 2000 |
| This invention relates to stabilized transglutaminase which is obtained by drying a solution containing transglutaminase and a protein material and to a transglutaminase enzyme preparation that contains the stabilized transglutaminase as an active ingredient, wherein a partial protein |
| 6028217 |
Optically active salts of 2-hydroxymethyl-3-phenylpropionic acid with cis-1-amino-2-indanol, .al |
February 22, 2000 |
| A compound selected from the group consisting of(a) optically active 2-hydroxymethyl-3-phenylpropionic acid cis-1-amino-2-indanol salt,(b) optically active 2-hydroxymethyl-3-phenylpropionic acid .alpha.-methylbenzylamine salt,(c) optically active 2-hydroxymethyl-3-phenylpropionic acid 3- |
| 6025421 |
Flame-retardant thermoplastic resin composition having improved humidity resistance and heat res |
February 15, 2000 |
| A flame-retardant thermoplastic resin composition, comprising 100 parts by weight of a thermoplastic resin, from about 5 to 100 parts by weight of an inorganic filler surface-treated with a phosphate represented by the following formula (A) and from about 5 to 50 parts by weight of an |
| 6025169 |
Process for production of lysine by fermentation |
February 15, 2000 |
| The present invention relates to a method for controlling carbon source concentration in the aerobic cultivation of a microorganism. The substrate carbon source remains at a low level in a cultivation vessel during the culture feeding in aerobic fed-batch, continuous or cell-recycling |
| 6025001 |
Method for producing bakery products |
February 15, 2000 |
| Shaped bodies of dough are expanded under reduced pressure and then subsequently baked under heat, or are baked under heat while being expanded under reduced pressure. There is no substantial final fermentation. |
| 6022581 |
Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing |
February 8, 2000 |
| Spherical aggregate crystals of a phosphoric acid/lysine/magnesium composite salt represented by formula (1):whereR is a lysine cation;a is 0.15 to 1.0;b is 1.0 to 1.42;c is 0 to 0.3;n is 0 to 10; anda+(2.times.b)+c=3. |
| 6015697 |
Method for producing nucleoside-5'-phosphate ester |
January 18, 2000 |
| A method for producing nucleoside-5'-phosphate esters inexpensively and in high yields by phosphorylating a nucleoside with a phospahte group donor using an acid phosphatase having an increased affinity for the nucleoside and/or an increased temperature stability at a pH of pH 3.0 to 5.5 |
| 6015696 |
Mycobacterial secretory expression vectors and transformants |
January 18, 2000 |
| A secretory vector expressed in mycobacteria comprising a promoter, a signal sequence having ligated therewith a DNA nucleotide sequence encoding heterologous polypeptide and replicator region capable of replication in mycobacteria is disclosed. A transformant that has been transform |
| 6013526 |
Modified protein for gene transfer and process for producing the same |
January 11, 2000 |
| The present invention relates to a process for producing a conjugate of a biologically active peptide or protein having at least one glutamine residue with a high-molecular weight substance containing an amino group. The present invention also relates to a composite of this conjugate wit |
| 6013498 |
Process for producing microbial transglutaminase |
January 11, 2000 |
| Disclosed are a protein having a transglutaminase activity, which comprises a sequence ranging from serine residue at the second position to proline residue at the 331st position in an amino acid sequence represented by SEQ ID No. 1 wherein the N-terminal amino acid of the protein corres |
| 6010851 |
Method for producing nucleoside-5'-phosphate ester |
January 4, 2000 |
| Nucleoside-5'-phosphate ester is produced inexpensively and efficiently by allowing an acid phosphatase, especially an acid phosphatase having a lowered phosphomonoesterase activity to act under a condition of pH 3.0 to 5.5 on a nucleoside and a phosphate group donor selected from the gr |
| 6010733 |
Aspartylamide derivatives and sweeteners |
January 4, 2000 |
| Novel aspartylamide derivatives such as N-(.alpha.-L-aspartyl-(1R,2S,4S)-1-methyl-2-hydroxy-4-phenylhexylamide, N-.alpha.-7(N'-3,3-dimethylbutylaspartyl)-(1R,2S,4S)-1-methyl-2-hydroxy-4- phenylhexylamide) and the like, and a sweetener containing the above-mentioned derivatives or salt |
| 6008390 |
Process for producing N-long-chain acyl acidic amino acids or salts thereof |
December 28, 1999 |
| N-long-chain acyl acidic amino acids or salts thereof are prepared by condensing an acidic amino acid or a salt thereof and a C.sub.8 -C.sub.22 long-chain fatty acid chloride in an aqueous solvent with stirring at a stirring power of not less than 0.2 kW/m.sup.3 while keeping the pH in t |
| 6004773 |
Method for producing L-lysine |
December 21, 1999 |
| A coryneform bacterium harboring an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, and comprising an enhanced DNA sequence coding for a dihydrodipicolinate reductase, an enhanced DNA sequence coding for dihydropicolinate reductas |
| 6000146 |
Apparatus and method for continuously granulating powder material |
December 14, 1999 |
| An apparatus for continuously granulating powder material has a feeder for continuously supplying powder material, and a granulation vessel. The granulation vessel includes a granulation zone and a drying zone. The apparatus also has a spray nozzle disposed so as to be declined above the |
| 5994545 |
Process for producing optically active amides |
November 30, 1999 |
| The present invention provides a process for producing decahydro(4as, 8aS)isoquinoline-3(S)-carboxamides which are useful as intermediates of Saquinavir (EP 432694). Saquinavir is an anti-AIDS agent. The comprises reacting tetrahydroisoquinoline-3(S)-carboxylic acid with at least one of |
| 5990167 |
Activity-inhibitor and activity-potentiator for glutamic acid in the brain |
November 23, 1999 |
| The present invention provides an activity-inhibitor for glutamic acid in the brain which comprises L-lysine or its derivatives. The present invention also provides an activity-inhibitor for glutamic acid in the brain which comprises L-arginine or its derivatives. The present invention |
| 5989875 |
Method of process for producing L-lysine by fermentation |
November 23, 1999 |
| A bacterium belonging to the genus Serratia, which is transformed by introducing into its cells, a DNA coding for a dihydrodipicolinate synthase originating from a bacterium belonging to the genus Escherichia or Serratia having mutation to desensitize feedback inhibition by L-lysine |
| 5985922 |
Amino acid derivatives and active oxygen-resisting agent |
November 16, 1999 |
| Provided is a novel active oxygen-resisting agent which has an excellent active oxygen resistance and which exhibits a good solubility in an oil solvent. An active oxygen-resisting agent containing as an active ingredient an amino acid derivative represented by the following formula |
| 5980957 |
Method for producing powdery seasoning |
November 9, 1999 |
| A method for producing powdery seasoning with constant quality, with no occurrence of coagulation under storage. The method comprises culturing koji mold in heated and expanded defatted soybean, maintaining a dispersion of the resulting culture in a sodium chloride solution under enz |
| 5977331 |
.alpha.-Ketoglutarate dehydrogenase gene |
November 2, 1999 |
| Disclosed are coryneform L-glutamic acid-producing bacteria deficient in .alpha.-ketoglutarate dehydrogenase, a method of producing L-glutamic acid by using the bacteria, a gene coding for an enzyme having .alpha.-KGDH activity originating from coryneform L-glutamic acid-producing bacter |
