| Patent Number |
Title Of Patent |
Date Issued |
| 6303359 |
DNA molecule encoding new aminopeptidase, and method of producing the aminopeptidase |
October 16, 2001 |
| Disclosed are cDNA encoding a new aminopeptidase derived from germinated soybeans, a recombinant expression vector containing the DNA, a transformant obtained by the transformation with the expression vector, and a method of producing an aminopeptidase by culturing the transformed pr |
| 6303353 |
Process for preparing xylitol |
October 16, 2001 |
| Xylitol is produced by contacting D-arabitol with a microorganism that belongs to the genus Gluconobacter, Acetobacter, Achromobacter, Agrobacterium, Arthrobacter, Azotobacter, Brevibacterium, Corynebacterium, Erwinia, Flavobacterium, Micrococcus, Nocardia, Planococcus, Pseudomonas, |
| 6303348 |
DNA coding for protein which confers on bacterium escherichia coli resistance to L-homoserine an |
October 16, 2001 |
| A bacterium which has an ability to produce an amino acid and in which a novel gene (rhtB) coding for a protein having an activity of making a bacterium having the protein L-homoserine-resistant is enhanced, is cultivated in a culture medium to produce and accumulate the amino acid in |
| 6303162 |
Process of injecting heat with a pickle solution |
October 16, 2001 |
| A curing agent comprising transglutaminase and a protein partial hydrolysate, and a pickle comprising same, having a controlled viscosity. |
| 6297031 |
Escherichia coli strain and method for producing L-threonine |
October 2, 2001 |
| E. coli strains derived form E. coli strain VNIIgenetika 472t23 and obtained by a process involving transduction by bacteriophage P1 which bears a transposon which inactivates threonine dehydrogenase activity and isolation of a transductant lacking threonine dehydrogenase activity are |
| 6296872 |
Tablet composition of N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine |
October 2, 2001 |
| A tablet composition containing N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine and low substituted hydroxypropylcellulose is disclosed. This tablet composition is rapidly disintegrated in the stomach after the administration and absorbed without being influenced by meals to |
| 6291634 |
Polyamino acid derivatives |
September 18, 2001 |
| Disclosed herein are the novel polyamino acid derivatives characterized in that at least four amino acid molecules are bound through the nitrogen atoms of the amino groups by crosslinking groups (e.g., alkylene groups which may have a hydroxyl group on, and/or an ether linkage in, the ca |
| 6291398 |
Plant-root growth promoting agent |
September 18, 2001 |
| Herein are disclosed, a plant-root growth promoting agent, which comprises inosine as the effective ingredient, as well as a method for promoting plant root growth, which comprise applying such plant-root growth promoting agent to the soil or, in the case of hydroponics, to the hydro |
| 6288155 |
Thermal stabilizer and thermally stabilized halogen-containing resin composition |
September 11, 2001 |
| A thermal stabilizer for halogen-containing resins, comprising a compound of the dolomite series and the zinc salt of an organic acid. The thermal stabilizer, when incorporated in a halogen-containing resin, provides an excellent thermal stabilizing effect for the resin. |
| 6284897 |
Method for crystallizing tryptophan |
September 4, 2001 |
| A method for the crystallization of tryptophan, comprising storing a tryptophan solution at a pH of 8 to 13 and at a temperature of room temperature to 100.degree. C. for 0.5 hour to 1 week and then, followed by crystallization. |
| 6284495 |
Method for producing nucleic acid substances |
September 4, 2001 |
| A nucleic acid substance is efficiently produced by cultivating a microorganism whose repressor protein for purine operon does not function in a normal manner, preferably a strain whose gene encoding the repressor protein on a chromosome (purR) is disrupted, in a culture medium so that |
| 6280972 |
Activator for methanol dehydrogenase and gene thereof |
August 28, 2001 |
| A cell which is introduced with a DNA coding for a protein defined in the following (A) or (B):(A) a protein which has the amino acid sequence of SEQ ID NO: 2 shown in Sequence Listing;(B) a protein which has the amino acid sequence of SEQ ID NO: 2 shown in Sequence Listing including sub |
| 6280731 |
Antithrombotic agent and anti-von willebrand factor monoclonal antibody |
August 28, 2001 |
| A monoclonal antibody, which has reactivity with human von Willebrand factor, which has action to inhibit RIPA (ristocetin-induced platelet aggregation), BIPA (botrocetin-induced platelet aggregation), and SIPA (shear stress-induced platelet aggregation) of human platelet, and which |
| 6262076 |
Pharmaceutical composition for use in the treatment of diabetic neuropathy |
July 17, 2001 |
| Disclosed is a pharmaceutical composition for use in the treatment of diabetic neuropathy, which comprises a piperidine derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof as an effective ingredient: ##STR1##wherein n is an intege |
| 6258975 |
Process for producing optically active 2-hydroxy-4-arylbutyric acid or its ester |
July 10, 2001 |
| Provided is an industrially useful process for producing an optically active 2-hydroxy-4-arylbutyric acid or its ester. An optically active acyloxysuccinic anhydride is reacted with an aromatic compound in the presence of a Lewis acid to produce an optically active 2-acyloxy-4-oxo-4- |
| 6258940 |
Method for producing erythrose |
July 10, 2001 |
| A method for producing erythrose, comprising subjecting glucose to a decomposition reaction using water at a super-critical state or at a sub-critical state as the solvent therefor, and a method for producing erythrose from glucose, wherein the reaction time is set to a time period s |
| 6258573 |
Method of producing L-serine by fermentation |
July 10, 2001 |
| Disclosed is a coryneform bacterium having resistance to azaserine or .beta.-(2-thienyl)-DL-alanine and having L-serine productivity. Also, disclosed are D-3-phosphoglycerate dehydrogenase derived from a coryneform bacterium, in which feedback inhibition by L-serine is desensitized; the |
| 6255086 |
Carbamoyl-phosphate synthetase gene of coryneform bacteria and method for producing L-arginine |
July 3, 2001 |
| A DNA fragment which encodes a polypeptide defined in the following (a) or (b), and a polypeptide defined in the following (c) or (d):(a) a polypeptide which has at least the amino acid sequence of the amino acid numbers 50 to 393 in SEQ ID NO: 2 shown in Sequence Listing,(b) a polypeptide w |
| 6252075 |
Process for producing purine derivatives |
June 26, 2001 |
| A process for preparing 7-benzylpurine derivatives is provided. An acetylpurine nucleoside is reacted with a benzyl halide to benzylate the 7-position of the purine base, and an acid is then added to the reaction mixture to hydrolyze the glycoside bond. The 7-benzylpurines may be used |
| 6251422 |
Method for reducing body fat accumulation in livestock or poultry |
June 26, 2001 |
| A feed composition for animals (livestock, poultry, fish or pet) which contains poly-.gamma.-glutamic acid (and/or degradated product thereof) and, a method for reducing body fat acumulation in animals which comprises feeding animals with a feed composition containing poly-.gamma.-glutam |
| 6245910 |
Process for producing purine derivatives |
June 12, 2001 |
| Purine derivatives in which a desired substituent is introduced into the 9-position only are synthesized by first introducing an easily-removable substituent in the 7-position of a purine base of natural purine nucleosides obtained through fermentation or derivatives thereof, then hy |
| 6242635 |
Process for producing propionic acid derivatives |
June 5, 2001 |
| A process for producing a 2-aralkyl-3-hydroxypropionic acid (or its ester), comprising the steps of: reacting a 3-hydroxy-2-methylene-3-arylpropionic acid ester, easily obtained by the reaction of an arylaldehyde with an acrylic acid ester, with an acid anhydride to form a 2-aralkyli |
| 6242228 |
Xylitol dehydrogenase of acetic acid bacteria and gene thereof |
June 5, 2001 |
| Xylitol is produced by allowing xylitol dehydrogenase or cells instoduced with a DNA coding for xylitol dehydrogenase, which is a protein of the following (A) or (B) to act on D-xylulose, and collecting produced xylitol:(A) a protein which has the amino acid sequence of SEQ ID NO: 4;(B) |
| 6239308 |
Method for producing .alpha.-hydroxy-.beta.-aminocarboxylic acids |
May 29, 2001 |
| The present invention provides a simple and inexpensive method for producing .alpha.-hydroxy-.beta.-aminocarboxylic acids and their esters.An ester of an N-protected .alpha.-amino acid ester is converted into a .beta.-ketosulfoxide, which is then processed with an acid to give an .alpha. |
| 6239305 |
Method for producing optically active phenylpropionic acid derivative |
May 29, 2001 |
| Optically active N-(S-2-acetylthiomethyl-1-oxo-3-phenylpropyl)-glycine benzyl ester useful as an enkephalin inhibitory agent or ACE inhibitory agent can be produced at low cost in an industrial manner, by a method comprising subjecting optically active 2-hydroxymethyl-3-phenylpropionic |
| 6238728 |
Mixed feed with an amino acid |
May 29, 2001 |
| An amino acid-enriched feed, industrially produced mixed feed or premix thereof which is obtainable by mixing (a) a feed raw material containing predominantly at least one feed component selected from the group consisting of corn gluten meal powder, corn gluten feed powder and an int |
| 6238727 |
Ruminant feed additive composition and process for producing the same |
May 29, 2001 |
| A ruminant feed additive composition containing (A) lysine magnesium phosphate, (B) magnesium oxide, (C) a binder and (D) water, said water content being between 5 and 15% by weight, and processes for producing the composition. |
| 6235775 |
Acetone adduct of fungicidal V-28-3M |
May 22, 2001 |
| The present invention provides an acetone adduct of V-28-3M to be used as an intermediate for producing V-28-3M which is useful as a fungicide, a process for producing it and a process for purifying V-28-3M. When crude V-28-3M is dissolved in acetone, an acetone adduct of V-28-3M is to |
| 6232426 |
Epoxy resin composition |
May 15, 2001 |
| Disclosed herein is a one-part polythiol-type epoxy resin composition having an excellent low-temperature quick curability and a good storage stability (shelf stability), which can be prepared by using, as essential components, (1) an epoxy resin having two or more epoxy groups per one |
| 6232323 |
Crystals of piperidine derivatives, intermediates for production of the same, and process for pr |
May 15, 2001 |
| Monohydrate and trihydrate crystals of N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-piperidino) ethyl)-1-formyl-4-piperidinecarboxamide hydrochloride having excellent stability. |
| 6228360 |
Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody |
May 8, 2001 |
| Anti-thrombotic agents containing humanized antibodies which bind to von Willebrand factor. |
| 6221972 |
Photosensitive resin and photosensitive resin composition containing the same |
April 24, 2001 |
| The present invention relates to a novel photosensitive resin which can be developed in water and which can be used as a photosensitive resin composition. More specifically, the present invention relates to a composition which is useful as a photosensitive soldering resist for printe |
| 6221636 |
Method for producing L-lysine |
April 24, 2001 |
| A recombinant DNA autonomously replicable in cells of coryneform bacteria, comprising a DNA sequence coding for an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, and a DNA sequence coding for a diaminopimelate decarboxylase; a coryne |
| 6221634 |
Method for producing xylitol or D-xylulose in bacteria |
April 24, 2001 |
| Xylitol or D-xylulose is produced through direct fermentation from glucose by culturing a microorganism belonging to the genus Gluconobacter, Acetobacter or Frateuria, and having an ability to produce xylitol or D-xylulose in a suitable medium to accumulate xylitol or D-xylulose in the |
| 6214591 |
Methods for producing L-valine and L-leucine |
April 10, 2001 |
| L-valine is produced by culturing a microorganism belonging to the genus Escherichia with the capability of producing L-valine or L-leucine wherein it requires lipoic acid for growth, a microorganism belonging to the genus Escherichia with the capability of producing L-valine or L-leucin |
| 6214371 |
Method for breeding highly lactiferous cows by using rumen-protective amino acids |
April 10, 2001 |
| Lysine and methionine which are limiting amino acids of dairy cows are administered to dairy cows to decrease the BUN value that has an adverse effect on the conception rate and to increase the blood glucose required to improve the energy balance, that alanine and glutamine are administe |
| 6210951 |
GMP synthetase and gene coding for the same |
April 3, 2001 |
| A protein which has a GMP synthetase activity, a DNA which codes for the protein and a transformant which is introduced with the DNA in a form that allows expression of the protein encoded by the DNA. |
| 6207834 |
Process for producing piperidinecarboxylic acid amide derivatives |
March 27, 2001 |
| A process for producing piperidinecarboylic acid amide derivatives useful as serotonin antagonists, antithrombocytic agents or intermediates for them, which comprises the step of reacting a 2-oxazoline compound with a piperidine derivative in the presence of an acid is provided. This pro |
| 6207435 |
Method for producing nucleoside-5'-phosphate ester |
March 27, 2001 |
| A method for producing nucleoside-5'-phosphate esters inexpensively and in high yields by phosphorylating a nucleoside with a phospahte group donor using an acid phosphatase having an increased affinity for the nucleoside and/or an increased temperature stability at a pH of pH 3.0 to 5.5 |
| 6197749 |
Method of suppressing immune responses by reducing intracellular content of glutathione in macro |
March 6, 2001 |
| A method of suppressing immune responses, comprising administering to a patient in need thereof an effective amount of a composition comprising a substance capable of reducing the content of reductive glutathione in macrophages. |
| 6197559 |
L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
March 6, 2001 |
| A method for producing L-glutamic acid which comprises culturing a microorganism belonging to the genus Klebsiella, Erwinia or Pantoea and having an ability to produce L-glutamic acid in a culture medium, and collecting produced L-glutamic acid from the culture medium. The microbial |
| 6197552 |
Process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine |
March 6, 2001 |
| A process for preparing 2,6-diaminopurine-2'-deoxyriboside and 2'-deoxyguanosine. These compounds may be used as materials for pharmaceuticals, such as antiviral agents and the like, and particularly as starting materials for antisense oligonucleotides. |
| 6184233 |
Crystals of piperidine derivatives, intermediates for production of the same, and process for pr |
February 6, 2001 |
| Monohydrate and trihydrate crystals of N-(2-(4-(5H dibenzo [a,d]cyclohepten-5-ylidene)-piperidino)ethyl)-1-formyl-4-piperidinecarboxa mide hydrochloride having excellent stability. |
| 6172224 |
Process for isolating 2-amino-6-chloro-9-[(1'S,2'R)-1'2'-bis(hydroxymethyl)-cyclopropane-1'-YL]m |
January 9, 2001 |
| A process for purifying 2-amino-6-chloro-9-[(1'S,2'R)-1',2'-bis(hydroxymethyl) cycdopropane-1'-yl]methylpurine represented by the following formula (5) comprises the step of selectively isolating 2-amino-6-chloro-9-[(1'S,2'R)-1',2'-bis(hydroxymethyl) cyclopropane-1'-yl]methylpuri |
| 6169200 |
Method for producing .alpha.-hydroxy-.beta.-aminocarboxylic acids |
January 2, 2001 |
| The present invention provides a simple and inexpensive method for producing .alpha.-hydroxy-.beta.-aminocarboxylic acids and their esters.An ester of an N-protected .alpha.-amino acid ester is converted into a .beta.-ketosulfoxide, which is then processed with an acid to give an .alpha. |
| 6166292 |
Raffinose synthetase gene, method of producing raffinose and transgenic plant |
December 26, 2000 |
| Raffinose synthase purified from cucumber is allowed to act on sucrose and galactinol. Thus raffinose is efficiently produced. The function of endogenous raffinose synthase is regulated by transforming a plant with a chimeric gene comprising a raffinose synthase gene and a regulatory reg |
| 6165756 |
Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine |
December 26, 2000 |
| A bacterial strain of Escherichia coli BKIIM B-3996, a producer of L-threonine, containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antiobiotics Research Institute under Reg. No. 1867. |
| 6162889 |
Curable resin composition for overcoat of flexible circuit |
December 19, 2000 |
| Herein is desclosed a curable resin composition comprising at least one polyol selected from the group consisting of Polyol A, including polybutadiene polyol (Polyol Aa), Polyol B, including polybutadiene polyol (Polyol Ba) and polyester polyol (Polyol Bb), and Polyol C, and at least |
| 6156886 |
Cytochrome bd type quinol oxidase gene of Brevibacterium lactofermentum |
December 5, 2000 |
| Oligonucleotides are synthesized based on amino acid sequences of the N-terminus of subunit I, and the N-terminus of subunit II of cytochrome bd type quinol oxidase of Brevibacterium flavum, PCR is performed by using the oligonucleotides as primers, and chromosome DNA of B. flavum as |
| 6156532 |
Stress-resistant microorganism and method of producing fermentative product |
December 5, 2000 |
| A microorganism is utilized to fermentatively produce useful substances such as amino acids by cultivating the microorganism in a medium to allow a fermentative product to be produced and accumulated in the medium, and collecting the fermentative product, wherein the microorganism to be |
