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Ajinomoto Co., Inc. Patents
Assignee:
Ajinomoto Co., Inc.
Address:
Tokyo, JP
No. of patents:
1341
Patents:












Patent Number Title Of Patent Date Issued
RE42350 Method for producing L-glutamic acid by fermentation accompanied by precipitation May 10, 2011
A microorganism is provided which can metabolize a carbon source at a specific pH in a liquid medium containing L-glutamic acid at a saturation concentration and the carbon source, and which has ability to accumulate L-glutamic acid in an amount exceeding the amount corresponding to the
RE41800 Method for producing l-glutamic acid October 5, 2010
A method for producing L-glutamic acid by fermentation, which comprises culturing a microorganism having L-glutamic acid-producing ability in a liquid medium of which pH is adjusted to a condition under which L-glutamic acid produced by the microorganism is allowed to be precipitated
RE38796 Process for producing 3-amino-2-oxo-1-halogenopropane derivatives September 13, 2005
Compounds formed by reacting a protected amino acid with an alkali metal enolate of an alkyl acetate are reacted with a halogenating agent for halogenation of the 2-position, or a protected amino acid is reacted with an alkali metal enolate of an alkyl halogenoacetate, to form a 4-am
RE38257 Piperdine derivatives and hypotensives containing the same September 23, 2003
A piperidine compound of the formula (I): ##STR1##wherein A is a fused aromatic ring; R is hydrogen, chloro or methoxy; X is (CH.sub.2).sub.n, which may be substituted, in which n is 0 or an integer of 1 to 10, --CH.ident.CH--, --C.ident.C--, --O--, --S--, --NH--, --N(COCH.sub.3)--,
RE37187 Aminopeptidase GX, and a method of hydrolyzing a protein with the same May 22, 2001
An aminopeptidase is provided which efficiently decomposes a low-molecular-weight peptide containing glutamic acid or aspartic acid in its sequence. A method of hydrolyzing a peptide or protein by use of the aminopeptidase is also provided. Aminopeptidase GX is derived from germinate
RE35609 Process for purifying 2',3'-dideoxynucleosides September 16, 1997
A biological process for producing a 2',3'-dideoxynucleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin absorbent.
RE34878 Hypoglycemic agent March 14, 1995
A compound of D-phenylalanine derivative for hypoglycemic use, represented by the general formula ##STR1## R.sup.1 is selected from hydrogen, alkyl of 1 to 5 carbon atoms, aryl of 6 to 12 carbon atoms, aralkyl of 6 to 12 carbon atoms, ##STR2## --CH.sub.2 CO.sub.2 R.sup.3, --C
8586334 Method for producing substance utilizing microorganism November 19, 2013
In a method for producing a target substance utilizing a microorganism comprising culturing the microorganism in a medium to produce and cause accumulation of the target substance in the medium and collecting the target substance, there is used, as the microorganism, a mutant strain or
8584352 Process for producing multilayer printed wiring board November 19, 2013
Multilayer printed wiring boards superior in formation of an ultrafine wiring, which can form a conductive layer superior in peel strength on a flat insulating layer surface, can be prepared by a method including the following steps (A)-(E): (A) a step of laminating a film with a metal
8580537 Thermotolerant transglutaminase originating in actinomyces November 12, 2013
The present invention provides transglutaminases with improved heat resistance. Specifically, the present invention provides mutant transglutaminase proteins with improved heat resistance as obtained by introducing appropriate mutations into transglutaminases, which results in the in
8574745 Resin composition and organic-electrolyte battery November 5, 2013
Provided is a resin composition superior in the adhesiveness to a metal and having high organic solvent resistance, particularly, a resin composition preferable as a sealant for an organic electrolyte battery, which shows superior adhesiveness to a terminal or a collector made of a h
8574466 Modified polyamine November 5, 2013
A pigment dispersant which includes a modified polyamine obtained by the reaction of a polyamine having two or more primary and/or secondary amino groups per molecule and containing 2 to 1800 nitrogen atoms per molecule, a polyester, and a phosphorus-containing compound. The modified pol
8569453 Fluorene compound October 29, 2013
Particular compounds having a fluorene skeleton are superior in broad utility and stability, as a protecting reagent for liquid phase synthesis of amino acids and/or peptides.
8568814 Lanthionine derivatives October 29, 2013
The present invention provides a variety of compounds having a CaSR agonist activity which possesses a superior kokumi-imparting function, and more particularly provides a kokumi-imparting composition, which contains the foregoing compound, and/or another substance having a CaSR agon
8563278 Process of producing glutamate derivatives October 22, 2013
A process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin is described. This process entails converting a substituted .alpha.-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing
8299064 Fused polycyclic compounds having a heterocyclic ring(s) and pharmaceutical use thereof October 30, 2012
The present invention provides a fused polycyclic compound of the following formula, analogues thereof and pharmaceutically acceptable salts thereof; and agents for increasing the sugar-transporting capacity, hypoglycemic agents and pharmaceutical compositions containing the above co
8298791 Purine-derived substance-producing bacterium and a method for producing purine-derived substance October 30, 2012
A purine-derived substance is produced by culturing a Bacillus bacterium which has an ability to produce a purine-derived substance and has enhanced activity of an enzyme of the oxidative pentosephosphate pathway. The purine-derived substance is produced in the medium or the bacterial
8293506 L-cysteine-producing bacterium and a method for producing L-cysteine October 23, 2012
The present invention provides a bacterium belonging to the family Enterobacteriaceae, which is able to produce L-cysteine and has been modified to increase the activity of the protein encoded by the dsbA gene. This bacterium is cultured in a medium, and L-cysteine, L-cystine, a deri
8293505 L-amino acid-producing microorganism and a method for producing an L-amino acid October 23, 2012
An L-amino acid is produced by culturing a microorganism which belongs to the family Enterobacteriaceae and is able to produce an L-amino acid, wherein the bacterium has been modified to enhance orotate phosphoribosyltransferase activity is enhanced, in a medium to produce and cause
8288526 Inosine derivatives and production methods therefor October 16, 2012
The present invention provides a method for producing an inosine derivative represented by the following general formula (1) including the steps of subjecting an inosine derivative of general formula (3) to dithiocarbonylation and carrying out radical reduction of the obtained compou
8278329 Diarylalkene derivatives and novel diarylalkane derivatives October 2, 2012
The invention relates to a compound represented by the following general formula (1) or its analogue, which selectively inhibit N-type calcium channels or its analogue, and to a method for treating pain etc. comprising the compound represented by the following general formula (1) or
8278075 L-cysteine-producing bacterium and a method for producing L-cysteine October 2, 2012
L-Cysteine, L-cystine, a derivative or precursor thereof, or a mixture thereof is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has L-cysteine-producing ability and has been modified so that the activity of a protein encoded by a tolC gene, for e
8278074 L-glutamic acid-producing microorganism and a method for producing L-glutamic acid October 2, 2012
A coryneform bacterium that is modified by using a yggB gene so that L-glutamic acid-producing ability is enhanced as compared to a non-modified strains is cultured in a medium to cause accumulation of L-glutamic acid in the medium or bacterial cells, and L-glutamic acid is collected
8273562 Method for producing 4-hydroxy-L-isoleucine September 25, 2012
A highly active L-isoleucine dioxygenase from Bacillus thuringiensis is provided. A method for manufacturing (2S,3R,4S)-4-hydroxy-L-isoleucine or a salt thereof by reacting L-isoleucine in an aqueous solvent in the presence of L-isoleucine dioxygenase and isolating (2S,3R,4S)-4-hydro
8273556 Aldolase and production process of substituted .alpha.-keto acids September 25, 2012
4-(Indol-3-ylmethyl)-4-hydroxy-2-oxoglutarate, which is useful as an intermediate in the synthesis of monatin, may be synthesized from indole pyruvic acid and pyruvic acid (and/or oxaloacetic acid) by using a novel aldolase derived from the genus Pseudomonas, Erwinia, Flavobacterium, or
8268844 Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dio September 18, 2012
Crystals of isopropyl ester of N-(2,6-dichlorobenzoyl)-4-[6-(methylamino)methyl-1-methyl-2,4-dioxo-1,4-d- ihydroquinazoline-3(2H)-yl]-L-phenylalanine hydrochloride: ##STR00001## are useful as .alpha.4 integrin inhibitors.
8263145 Enzyme preparation and process for producing food using the same September 11, 2012
The present invention provides an enzyme preparation containing, as the active ingredient, an acidic or alkaline substance capable of shifting the pH value of the preparation toward a pH range wherein the expression of activity of a transglutaminase is inhibited when the transglutaminase
8252920 Inosine derivatives and production methods therefor August 28, 2012
The present invention provides a method for producing an inosine derivative represented by the following general formula (1) including the steps of subjecting an inosine derivative of general formula (3) to dithiocarbonylation and carrying out radical reduction of the obtained compou
8252355 Method of producing cooked rice by intermittent heating August 28, 2012
A method of producing cooked rice is disclosed, by which taste and mouthfeel, as well as the aging resistance, of the cooked rice are improved. In this method, process of cooking rice is carried out intermittently in a plurality of steps, interposing one or more cooling steps during
8247201 Method for producing an organic acid August 21, 2012
An organic acid is produced by allowing a bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an organic acid and has been modified so that the phosphoenolpyruvate carboxykinase activity is enhanced, which is selected from Enterobacter, Pantoea, Erwi
8247193 Method for producing .alpha.-L-aspartyl-L-phenylalanine-.beta.-ester and method for producing .a August 21, 2012
A method of producing an .alpha.-L-aspartyl-L-phenylalanine-.beta.-ester by forming the .alpha.-L-aspartyl-L-phenylalanine-.beta.-ester from L-aspartic acid-.alpha.,.beta.-diester and L-phenylalanine using an enzyme or enzyme-containing substance that has an ability to selectively li
8244476 Hepatic disease-evaluating apparatus, hepatic disease-evaluating method, hepatic disease-evaluat August 14, 2012
In a hepatic disease-evaluating apparatus, an indicator calculating unit calculates an index indicating the degree of hepatic fibrosis from amino acid concentration data to be evaluated including amino acid concentration value, based on one or more indices of fractional expression ha
8236531 Purine-derived substance-producing bacterium and a method for producing a purine-derived substan August 7, 2012
A purine-derived substance is produced by culturing a bacterium belonging to the genus Bacillus which has an ability to produce a purine-derived substance and has been modified so that enzymatic activity of transaldolase is decreased in a medium to cause accumulation of a purine-deri
8234075 Apparatus and method for processing information concerning biological condition, system, program July 31, 2012
A system provided in accordance with the present invention comprises a sever unit (100), which serves as an apparatus for processing information concerning a biological condition information, and a client unit (200), which serves as an information terminal of a provider of the informatio
8227214 Method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with atten July 24, 2012
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
8226628 Communicating needle for connecting two or more containers to communicate July 24, 2012
An object is to provide a communicating needle of simple construction which is attached to a medical infusion bag to connect two or more containers in fluid communication with each other. The communicating needle for connecting two or more containers to communicate includes a tip hav
8222405 Phenylalanine derivatives July 17, 2012
Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to .alpha.4 integrin. They are used as therapeutic agents for various diseases concerning .alpha.4 integrin. ##STR00001##
8222007 L-glutamic acid producing bacterium and a method for producing L-glutamic acid July 17, 2012
The present invention describes an L-glutamic acid-producing bacterium which belongs to the genus Pantoea, Enterobacter, Klebsiella or Erwinia, wherein the bacterium has been modified by gene recombination to inactivate the rpoS gene. A method is also described for culturing the bact
8212068 Ester derivative and use thereof July 3, 2012
A compound represented by the following formula (I') ##STR00001## wherein X.sub.1 is a methylene group, an ethylene group, a trimethylene group or a vinylene group, X.sub.2 is a divalent group represented by the following formula A or B, ##STR00002## Y is an ethylene group or a vi
8206954 L-amino acid-producing microorganism and a method for producing an L-amino acid June 26, 2012
An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has an L-amino acid-producing ability and inherently has a native activity of a glucose dehydrogenase that uses pyrroloquinoline quinone as a coenzyme, but has been modified so that the
8202711 Process for producing glutamate derivatives June 19, 2012
The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted .alpha.-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing
8198478 Method of producing alpha-form glutamic acid crystals June 12, 2012
This present invention provides crystallization of .alpha.-form crystals preferentially which are metastable crystals without precipitating .beta.-form crystals. This method allows for the precipitation of .alpha.-form crystals which are metastable crystals by combining (a) the proce
8198053 Method for producing basic substance June 12, 2012
A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate an
8197874 Method of preparing baked egg June 12, 2012
A method of producing baked egg using a horizontal rotating cylinder-type continuous frying apparatus, which baked egg has a small size and a strong fried flavor, is disclosed. Egg liquid is sprayed onto the inner surface of a heating drum while rotating the heating drum to solidify the
8193137 Thickening composition June 5, 2012
The present invention provides a thickening composition simultaneously exhibiting suitable thickening performance and superior usability, which contains N-long-chain acyl acidic amino acid and/or a salt thereof, an amphipathic substance, an inorganic salt, and water as essential comp
8192963 Bacterium capable of producing L-amino acid and method for producing L-amino acid June 5, 2012
A bacterium is described which belongs to the Enterobacteriaceae family, and has an ability to produce an L-amino acid, such as L-glutamic acid, L-arginine and L-threonine. The bacterium is modified so that the activity of a protein encoded by ydcI gene is decreased, thereby producin
8192770 Enzyme preparation for adhesion-molded foods and method for producing adhesion-molded food June 5, 2012
By using transglutaminase with calcium chloride or magnesium chloride as active ingredients, food raw materials such as meat pieces can be sufficiently adhesion-molded without using a protein material.
8187850 Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family with att May 29, 2012
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of the ybiV gene.
8187835 Method for producing protein May 29, 2012
By culturing a methanol-assimilating bacterium which harbors a DNA construct which contains a promoter sequence that functions in the methanol-assimilating bacterium and a nucleotide sequence that encodes a polypeptide containing a signal sequence and an objective protein which is fu
8187579 Thickening agent May 29, 2012
Thickening agents which containing a specific N-acylamino acid (component A) and a specific amideamine (component B) are capable of generating, when used in combination with a wide variety of oily bases including a hydrocarbon oil and silicone, a creamy thickening composition having a

 
 
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