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AVL Medical Instruments AG Patents
Assignee:
AVL Medical Instruments AG
Address:
Schaffhausen, CH
No. of patents:
63
Patents:


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Patent Number Title Of Patent Date Issued
D415839 Diagnostic flow through cell device October 26, 1999
6238930 Layer structure for determination of analyte concentration based on micellar recognition system May 29, 2001
Starting from two non-miscible phases, i.e., a lipophilic and a hydrophilic phase, a surface-active substance and a recognition component, a micellar recognition system is built in a suitable manner and is incorporated into a layer structure. The micellar recognition system is provided i
6174728 Control or calibration standard for use with instruments for optical measurement of hemoglobin c January 16, 2001
A control or calibration standard for use with instruments for the optical measurement of the hemoglobin content in blood samples, features scattering particles or beads dispersed in aqueous electrolyte solution. To prevent sedimentation of the beads during storage, they have a mean
6103197 Method and apparatus for optically determining total hemoglobin concentration August 15, 2000
In a method of optically determining the total hemoglobin concentration (tHb) in non-hemolyzed whole blood, using at least two wavelengths for measuring, a first wavelength of .lambda.<805 nm and a second wavelength of .lambda.>805 nm is employed, such that the following is valid f
6099510 Device for withdrawing a liquid from a sealed glass ampoule August 8, 2000
A device for withdrawing a liquid from a sealed glass ampoule includes a frame holding the sealed glass ampoule in upright or slightly inclined position, such that a tip of the ampoule points upwardly. An element is provided which will press or knock against the side of the tip or neck o
6047719 Method and device for production of high-precision, continuous streams of mixed gas April 11, 2000
In a gas mixing system for producing high-precision, continuous streams of mixed gas consisting of a plurality of individually metered gas components, with an individual gas line including a pressure reducing element and, if desired, a precision pressure regulator for each gas compon
6046055 Luminescence-optical method and sensor layer for quantitative determination of at least one chem April 4, 2000
In a sensor layer for quantitative determination of at least one chemical component in a gaseous or liquid sample medium containing a chromophore which is directly or indirectly responsive to the component being determined by changing its absorption spectrum, and a luminophore which is
6040190 Method for determining the concentration C of an absorbent homogeneously distributed in a carrie March 21, 2000
For the purpose of determining the concentration c of an absorbing medium distributed homogeneously in a carrier, even if the film thickness d of the carrier is unknown, an absorbing medium is used whose measured absorption a(.lambda.) deviates from Lambert-Beer's law, in particular in
6037178 Method for quality control of an analyzing system March 14, 2000
Quality control of an analyzing system that includes a portable analyzer with insertable single-use cartridges whose sample chamber contains optical and/or electrochemical sensors is accomplished by bringing the sensors in the single-use cartridge into contact, or are in contact with,
6001228 Device for performing measurements in fluids December 14, 1999
A device for performing electrochemical and/or optical measurements in fluids, includes a sensor part of substantially planar configuration carrying a plurality of sensors that are connected to conductive paths; a cover part, which includes a groove-shaped measuring channel through which
5948366 Glass ampoule for holding a drug a calibration liquid or a quality control liquid September 7, 1999
In a glass ampoule for holding a drug, a calibration liquid or a quality control liquid, whose bottom is flat or recessed towards the interior of the ampoule, the bottom area is shaped and/or coated such that a predefined breaking site is provided, which can be mechanically destroyed
5942189 Luminescence-optical method and sensor layer for quantitative determination of at least one chem August 24, 1999
In a sensor layer for quantitative determination of at least one chemical component in a gaseous or liquid sample medium containing a chromophore which is directly or indirectly responsive to the component being determined by changing its absorption spectrum, and a luminophore which is
5928957 Determination of analyte concentration based on a micellar recognition system and structured lay July 27, 1999
Starting from two non-miscible phases, i.e., a lipophilic and a hydrophilic phase, a surface-active substance and a recognition component, a micellar recognition system is built in a suitable manner and is incorporated into a layer structure. The micellar recognition system is provided i
5928918 Preparation of a hydrophobic polymer matrix containing immobilized enzymes July 27, 1999
Biological components such as enzymes are immobilized in a three-dimensional cross-linked hydrophobic polymer. An enzyme is mixed with an aqueous solvent and a non-crosslinked prepolymer having an essentially nonpolar main chain with attached polar hydrophilic groups and cross-linkin
5898487 Apparatus and method for determining the concentrations of hemoglobin derivatives April 27, 1999
An apparatus for determining the concentrations of n hemoglobin derivatives in a sample of undiluted, unhemolyzed whole blood provided in a cuvette, employs a device producing a primary light beam formed of at least n substantially monochromatic, narrow-band components of different w
5866433 Optochemical fluorescence sensor and method for measuring the concentration of at least one anal February 2, 1999
An optochemical fluorescence sensor with a biorecognitive layer for measuring the concentration of one or more analytes in a sample is provided with at least one island layer which is applied on a sensor substrate. The islands of the island layer are in the form of electrically-condu
5779978 Measuring assembly for luminescence analysis July 14, 1998
A measuring assembly comprises a supporting element transparent to excitation and measurement radiation, which is provided with a number of preferably different luminescence-optical sensor elements on a first boundary face. Via a second boundary face excitation radiation can be picke
5773301 Method for optically determining total hemoglobin concentration June 30, 1998
In a method of optically determining the total hemoglobin concentration (tHb) in non-hemolyzed whole blood, using at least two wavelengths for measuring, a first wavelength of .lambda.<805 nm and a second wavelength of .lambda.>805 nm is employed, such the following is valid for th
5723340 Optical indicator for determining the activity of an ion in a sample March 3, 1998
An optical indicator for determining the activity of an ion in a sample is provided with an ionophor which is capable of selectively binding the ion to be measured. The ionophor has at least two functional groups that can form an electron donor acceptor (EDA) complex, the complex bond be
5683658 Reagent bottle November 4, 1997
A reagent bottle suitable for insertion into a sample analyzer features a sample discharge opening plugged by an elastic, pierceable stopper, and an air inlet. Both the sample discharge opening and the air inlet are located on the same side of the reagent bottle, the axes of the two open
5683562 Planar sensor for determining a chemical parameter of a sample November 4, 1997
A planar sensor for determining a chemical parameter of a sample, includes a substrate whose surface is at least partly plane and is provided with at least one potentiometric or amperometric and, possibly, an optical transducer, and one or more biochemical components. The transducer and
5658451 Method for calibration of a pH measuring element August 19, 1997
In a method for calibration of a pH measuring element whose ion-permeable, hydrophilic polymer layer is brought into contact with an aqueous solution prior to calibration, the aqueous solution is displaced or replaced by a gaseous calibrating medium, and residues of the aqueous solution
5628353 Method and device for withdrawing a liquid from a sealed glass ampoule May 13, 1997
For the purpose of automatically drawing a liquid from a sealed glass ampoule the latter is held in a support in upright position with the ampoule bottom facing upwards, and the bottom is destroyed mechanically by inserting a withdrawing element. The liquid content of the ampoule is then
5627504 Electromagnetic actuating device, in particular for a valve May 6, 1997
Electromagnetic actuating device, in particular for a valve, includes a plunger which is axially movable between two extreme positions, an electromagnetic coil surrounding the plunger actuating it, and a permanent magnet holding the plunger in one of its extreme positions, and at least
5611998 Optochemical sensor and method for production March 18, 1997
An optochemical sensor for measuring concentrations of analytes is provided with a reactive matrix preferably made of polymeric material capable of swelling. Further provided are a mirror layer and a layer of a plurality of discrete islands that are electrically conductive, between which
5551437 Sensor for measuring blood pressure September 3, 1996
A sensor with a first, second and third force pick-up includes a piece of foil made of piezoelectric material which serves all three pick-ups and carries a number of electrodes. The second and third pick-up are located one on either side of the first pick-up and are characterized by a sm
5527706 Method for mixing two initial solutions June 18, 1996
In a process for mixing two initial solutions to produce a working solution with an accurately defined mixing ratio, the two initial solutions are coarsely mixed in a first step, having a mixing ratio lying within a given range, and the value of an internal parameter of the working solut
5513859 Sealing element May 7, 1996
A fluid-tight connection of capillary channels in components which are detachable from each other is established with the use of a sealing element. In order to compensate for slight deviations between the channel axes during the coupling of the components without creating any dead sp
5507936 Member for the formation of at least one electrode and/or one sensor April 16, 1996
A member has a solid carrier and a thin oxide layer which is arranged thereon and consists of iridium oxide and/or possibly at least one oxide of at least one other metal belonging to the fifth or sixth period and to one of the subgroups 5b, 6b, 7b and 8 of the Periodic Table of chemical
5496521 Analyzing device including an ion-permeable channel connecting a sample chamber with a reaction March 5, 1996
In a device for determining the concentration of a reagent from a group consisting of gases with acid or alkaline reaction in aqueous environments, and volatile acids and bases in liquid or gaseous samples, a sample chamber is situated in a housing and a unit for pH measurement with
5489515 Device for analyzing the metabolism of cells February 6, 1996
A device for analyzing the metabolism of cells includes a supporting base which carries a pH measuring electrode, a control electrode designed for proton exchange with the liquid, a reference electrode, and a counterelectrode, and which, together with at least one other part, confine
5474276 Valve for control of a branch line December 12, 1995
In order to avoid dead volumes in a valve for control of a branch line departing from the main line in a valve chamber located in a valve housing, the valve chamber contains an elastomer part provided with a main channel and a branch channel departing from it, and the two ends of the
5464587 Luminescence-optical indicator for determining the activity of alkali metal ions in a sample sol November 7, 1995
A luminescence-optical indicator for determining the activity of alkali metals based on decay time includes at least three components that are chemically bound to one another, i.e., a fluorophor, a functional group with which the luminescence decay time of the fluorophor can be influ
5441701 Feeder unit for selectively charging an analyzing apparatus August 15, 1995
A feeder unit, which is used for selectively charging an analyzing apparatus with liquid or gaseous sample-, reference- or cleaning media, comprises a sample inlet and a feeder part hinged on the feeder unit at one end. The feeder part contains an intake passage for the cleaning medi
5441625 Electrode arrangement August 15, 1995
An electrode arrangement includes at least one potentiometric measuring electrode located in a sample channel, a reference electrode located in a branch line, and a suction pump downstream of the diaphragmless entrance opening of the branch line into the sample channel the reference elec
5407829 Method for quality control of packaged organic substances and packaging material for use with th April 18, 1995
For quality control of packaged organic substances, preferably packaged foods and drugs, the materials to be examined are brought into contact with a planar optical sensor element which is applied on the inside of the wrapping and responds to a change in the gas composition in the gas sp
5386834 Apparatus for withdrawing arterial blood February 7, 1995
Apparatus for withdrawing arterial blood has a protective tube having a mounting member on one end of the tube. The mounting member includes a conical seat for the receipt of a hollow needle. A connecting member is mounted on the other end of the tube. First and second capillaries, havin
5373855 Two-channel needle for withdrawing body fluids December 20, 1994
A two-channel sampling needle is designed for withdrawing body fluids, such as blood or tissue fluid, has two essentially parallel cannulas, the first cannula being provided with an insertion needle which may be removed after the sampling needle has been introduced, its sharpened end pro
5372582 Probe for dialysis December 13, 1994
A dialytic probe is provided with an insertion needle sharpened at one end, which is surrounded by a flexible plastic cannula, and may be removed after introduction of the probe. The plastic cannula is covered at least partly by a tubular dialyzing membrane which is bonded to the plastic
5368027 Sensor arrangement for direct or indirect optical determination of physical or chemical properti November 29, 1994
In a sensor arrangement for direct or indirect optical determination of physical or chemical parameters, in human and animal bodies, the sensor arrangement including an indicator cell which is permeable to the chemical substance or physical quantity to be measured and which contains one
5353792 Sensing device October 11, 1994
In order to simultaneously determine the concentrations of different analytes in several places in a tissue by means of a thin, biocompatible tube or cannula which is inserted into the tissue, the tube is provided with several areas along its length which contain either identical or
5351563 One-way measuring element for analyzing gaseous or liquid samples October 4, 1994
Method for analyzing gaseous or liquid samples, utilizing a one-way measuring element with a measuring channel containing at least one optical or electrochemical sensor and being provided with sealing elements on either end. In order to obtain accurate measurements in a simple manner
5340722 Method for the determination of the concentration of an enzyme substrate and a sensor for carryi August 23, 1994
A method for the continuous and reversible determination of the concentration of an enzyme substrate such as glucose in an specimen, wherein the specimen is brought into contact with a corresponding enzyme selected from oxidases and oxygenases and to which a flavin coenzyme (FMN, FAD
5325867 Device for withdrawing body fluids July 5, 1994
A device for the sampling of body fluids using a hollow needle (6), is provided with a storage system (3) with several separate sample containers (4) placed on a movable carrier (9). The containers (4) which are sealed by puncturable membranes (5) so as to be gas-tight, will receive coll
5309916 Blood pressure measuring device and method May 10, 1994
A device for measuring blood pressure includes a sensor arrangement which is releasably attached to the exterior of a body and which is electrically conductively connected with electronic circuit. The sensor arrangement and the circuit are configured to determine, in at least one measuri
5308581 Substance of an optical fluorescence measuring arrangement for measuring the pH of a sample and May 3, 1994
An indicator for use in a luminescence-optical configuration for continuous and reversible measurement of the pH of a sample within a relevant measuring range (M), whose luminescence decay time .tau. is dependent on the pH of the sample, is characterized by the following properties. The
5299570 System for measuring the saturation of at least one gas, particularly the oxygen saturation of b April 5, 1994
A system for measuring the saturation of at least one gas in blood has a sensor which is, intended to be placed on a living body. Light is emitted from the sensor and into the body at a light radiating zone. The sensor has a plurality of light receiving zones, serving to receive light
5270008 Analyzing device December 14, 1993
An analyzing device, in particular for examining body fluids, with a measuring module, at least one gas feed tube for a calibrating gas, a moistening device for the calibrating gas as well as a washing water tube connectable to the measuring channel of the measuring module, is simpli
5266180 Interior electrode of a polarographic electrode November 30, 1993
In order to simplify manufacture of the interior electrode of a polarographic electrode with an electrically insulating shell containing a wire lead and carrying a reactive surface at its front end, which surface is formed by the free cross-sectional areas of wires arranged in the shell
5265843 Electromagnetically actuated valve November 30, 1993
Electromagnetically actuated valve, comprising an actuating device, a movable plunger and a valve chamber with an opening for the medium passing through it, which opening may be closed by the plunger. In order to ensure safe functioning of the valve at small closing forces, the valve cha
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