| Patent Number |
Title Of Patent |
Date Issued |
| 5948800 |
Preventive or therapeutic drug for Alzheimer's disease |
September 7, 1999 |
| The present invention is directed to a drug for preventing or remedying Alzheimer's disease. The drug contains as the active ingredient 2-phenyl-1,2-benzisoselenazol-3(2H)-one (referred as compound (A)), whose effect is based on the action of reducing neuron toxicity induced by .beta |
| 5741517 |
Water-containing liposome system |
April 21, 1998 |
| An aqueous liposome system which contains at least one phospholipid and selectively a non-toxic organic solvent. In addition to the at least one phospholipid the liposome system contains at least one phospholipidic charge carrier. |
| 5556637 |
Water containing liposome system |
September 17, 1996 |
| An aqueous liposome system which contains at least one phospholipid and selectively a non-toxic organic solvent. In addition to the at least one phospholipid the liposome system contains at least one phospholipidic charge carrier. |
| 5321145 |
Process of producing phosphatidylcholine derivatives |
June 14, 1994 |
| A process of producing phosphatidylcholine derivatives by the reaction of glycerophosphatidylcholine with at least one fatty acid anhydride in the presence of a pyridine catalyst is described. The reaction is carried out in a melt of the glycerophosphatidylcholine, the at least one fatty |
| 5176935 |
Baking agent for breakfast roll doughs |
January 5, 1993 |
| A baking agent for breakfast-roll doughs includes a phospholopid fraction in which the portion of phosphatidyl choline to phosphatidyl ehtanolamine is greater than 1. A method for producing such a baking agent is also included. |
| 5141955 |
Anti-inflammatory benzylselenobenzamides made from anilines and benzylamines |
August 25, 1992 |
| Anti-inflammatory benzylselanobenzamides made from anilines and benzylamines have the formula I ##STR1## are disclosed wherein R is hydrogen, methyl or ethyl;R.sup.1 and R.sup.2 are the same or different and, taken separately, are hydrogen, fluorine, chlorine, bromine, C.sub.1 to C.s |
| 5129950 |
Process of improving activity of herbicides and fertilizers using N-(2-hydroxyethyl)-acetamide o |
July 14, 1992 |
| The invention is related to the use of certain water-soluble compounds known as such and having the Formulafor the modulation of membrane dependent metabolism processes within living cells, in particular with relation to transport phenomena and cell procedures which are induced or influe |
| 5126357 |
Anti-inflammatory picolyselenobenzamides and salts thereof |
June 30, 1992 |
| A compound or a pharmaceutically acceptable salt thereof, having anti-inflammatory activity, is disclosed according to the Formula (I) ##STR1## wherein R is hydrogen, methyl or ethyl,R.sub.1 is a 2-pyridyl, 3-pyridyl or 4-pyridyl group or is phenyl, chlorophenyl or fluorophenyl,R.sub |
| 5114954 |
Antiinflammatory benzylselenobenzamides from aminopyridines and picolylamines |
May 19, 1992 |
| Benzylselenobenzamides of formula I ##STR1## with inflammation-inhibiting characteristics and used in pharmaceutical preparations. |
| 5114928 |
Phospholipid-containing composition, a process for its preparation and its use as an excipient f |
May 19, 1992 |
| The invention relates to a solid phospholipid composition with a high phosphatidylcholine content which, in addition to the corresponding phospholipids, contains Palatinit and if appropriate one or more other auxiliaries, and a process for its preparation and its use as an oral prese |
| 5093354 |
Topical use of 2',4',6'-trimethoxy-4-(1-pyrrolidinyl) butyrophenone |
March 3, 1992 |
| A method of treating obstruction dermatoses, ulcus cruris, ulcus cruris venosum and decubital ulcers, is disclosed, which comprises topically treating an affected patient with a therapeutically effective amount of a pharmaceutical composition containing as active ingredient a therape |
| 5021242 |
Solid drug preparations containing micronized crystals of ebselen |
June 4, 1991 |
| The invention is related to solid drug preparations of 2-phenyl-1,2-benzisoselenazol-3(2H)-one (EBSELEN) with high bioavailability comprising EBSELEN in the form of micronized crystals, and a method of manufacturing the same. |
| 5008394 |
Process for producing ebselen in highly pure form |
April 16, 1991 |
| The invention is related to a process for preparing highly pure Ebselen (2-phenyl-1.2-benzisoselenazole-3(2H)-one) of formula ##STR1## |
| 4983327 |
Process for isolating a phosphatidylcholine free of other phospholipids in the starting material |
January 8, 1991 |
| A process for isolating a phosphatidylcholine from vegetable lipid mixtures wherein the lipid mixture is dissolved in a solvent mixture of a low boiling petroleum ether fraction (40.degree.-80.degree. C.), a lower C.sub.1 -C.sub.4 -alkanol and water, the solution is introduced into a |
| 4906813 |
Device and process for marking molded items and tablets with laser beams |
March 6, 1990 |
| Process and device for applying markings (9) and/or providing break notches on moulded items or tablets (4) by means of laser beams. The installation (16) which produces the laser beam (3) is arranged on a tablet-producing press, to which it is functionally connected by synchronization s |
| 4874553 |
Aqueous phospholipid solutions containing a solubilizing agent |
October 17, 1989 |
| Liquid phospholipid-containing products in an aqueous medium which contains 5-80% by weight of phospholipids and 3-10% by weight of one or more compounds of the general formulatheir preparation and their use, for example as additives for improving plant treatment agents. |
| 4873350 |
Diselenobis-benzoic acid amides of primary and secondary amines and processes for the treatment |
October 10, 1989 |
| The present invention relates to new diselenobis-benzoic acid amides of primary and secondary amines of the general formula (I): ##STR1## and processes for the treatment of diseases in humans caused by a cell injury. |
| 4842865 |
Use of glycofurol for the liquidization of pharmaceutical preparations to be filled into soft ge |
June 27, 1989 |
| Use of glycofurol for the liquidization of pharmaceutical preparations containing more than 50% phosphatidyl choline with a high content of unsaturated fatty acids, which preparations can contain another active ingredient as well as phosphatidyl choline, and in which the viscosity so |
| 4784994 |
Process for the treatment of inflammatory and allergic diseases |
November 15, 1988 |
| The invention relates to a process for the treatment of inflammatory and allergic skin diseases. |
| 4774252 |
Benzisoselenazolonyl derivatives and processes for the treatment of rheumatic disease |
September 27, 1988 |
| The present invention relates to new benzisoselenazolonyl derivatives of the general formula (I) ##STR1## and processes for the treatment of rheumatic diseases. |
| 4757063 |
Process for the treatment of diseases caused by oxidative stress |
July 12, 1988 |
| The invention is related to a process for the treatment of diseases caused by oxidative stress in human beings comprising administering to said human being a pharmaceutical preparation comprising 2-phenyl-1,2-benzisoselenazol-3(2H)-one as active agent in an amount of 10 to 2000 mg pe |
| 4730053 |
S-[2-phenyl (alkyl) carbamoyl]-phenylselenylmercapto derivatives |
March 8, 1988 |
| The present invention is related to new S-(Carbamoyl-phenylselenyl) derivatives of mercaptanes of the general formula (I) ##STR1## and to a process for the treatment of diseases caused by cell injury due to the increased formation of active oxygen metabolites. |
| 4720550 |
Process for producing imidazolylthiophenaldehydes |
January 19, 1988 |
| The invention is related to a new process for producing imidazolylthiophenaldehydes of the general formula I ##STR1## |
| 4711961 |
Benzisoselenazolethiones and process for the treatment of various diseases in humans |
December 8, 1987 |
| The invention relates to new benzisoselenazolethiones of the general formula I ##STR1## and to processes for the treatment of various diseases by administering them to such beings. |
| 4705802 |
Omega-aryl-alkylthienyl-compounds and process for the treatment of chronically inflammatory proc |
November 10, 1987 |
| The invention relates to new .omega.-aryl-alkylthienyl compounds having the Formula I ##STR1## i.e. omega-aryl-alkyl thienyl alkanoic acids and, respectively, omega-aryl-alkyl thienyl alkenoic acids, the alkali metal salts of such acids and certain esters thereof. The invention f |
| 4699914 |
Imidazole group containing 2(1H)-pyridones and method for treating heart insufficiencies in huma |
October 13, 1987 |
| The present invention is directed to new, an imidazole group containing 2(1H)-pyridones of formula I ##STR1## salts thereof and process for treating congestive heart failure in humans. |
| 4684632 |
Formulation with special 1,2-diacylglycero-3-phosphocholines for the treatment of gastrointestin |
August 4, 1987 |
| Pharmaceutical formulations for the treatment of gastrointestinal disorders, which contain as the active component an effective gastrointestinal disorder alleviating amount of a 1,2-diacylglycero-3-phosphocholine in which 75-86% by weight of the acyl radicals are unsaturated fatty ac |
| 4681617 |
Phospholipid compositions and their use in plant protection spray mixtures |
July 21, 1987 |
| Phospholipid concentrates from natural or synthetic phospholipids and physiologically acceptable organic solvents and further additives of the following composition:20-60 wght. % phospholipids0-23 wght. % glycerin5-62.5 wght. % organic solvent0-30 wght. % co-emulsifier0-35 wght. % dissolving |
| 4667033 |
Substituted 6-(thien-2-yl)-3(2H)-pyridazinones |
May 19, 1987 |
| The invention refers to substituted 6-(thien-2-yl)-3(2H)-pyridazinones of Formula I ##STR1## |
| 4661487 |
Process for reducing reflex tachycardia in the treatment of hypertension employing a combination |
April 28, 1987 |
| The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (.+-.)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl |
| 4654358 |
1,4,5-triphenylimidazol-2-yl mercapto alkanoic acids, useful against inflammation and diseases r |
March 31, 1987 |
| The invention is related to imidazol-2-yl mercapto alkanoic acids having the formula I ##STR1## process for the treatment of humans suffering from inflammatory diseases or diseases in relation with the lipid metabolism. |
| 4618669 |
S-(carbamoyl-phenylselenyl) derivatives of glutathione and of aminomercaptocarboxylic acids |
October 21, 1986 |
| The present invention relates to new S-(carbamoylphenylselenyl) derivatives of glutathione and of .alpha.-aminomercaptocarboxylic acids of the general formula (I) ##STR1## |
| 4610979 |
O-acyl-alkanediol-phospholipids and processes for the treatment of asthma |
September 9, 1986 |
| The invention relates to new O-acyl-alkanediol-phospholipids of the general formula I ##STR1## processes for their preparation and process for the treatment of certain diseases in humans. |
| 4600722 |
3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines and a process for the treatment of i |
July 15, 1986 |
| The invention relates to new 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines of the Formula I ##STR1## and acid addition salts thereof and a process for the treatment of inflammatory and allergic processes in humans. |
| 4599205 |
1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids |
July 8, 1986 |
| The invention is related to 1-O-alkyl-3-amino-propan-1.2-diol-2-O-phospholipids having the formula I ##STR1## |
| 4576626 |
Foliage fertilizers |
March 18, 1986 |
| New foliage fertilizers containing one or more macronutrients and/or one or more micronutrients as well as 10 to 50% by weight (referred to total nutrients) of one or more phospholipids. |
| 4565659 |
Substituted aminoalkanol phospholipids |
January 21, 1986 |
| The invention concerns new substituted aminoalkanol phospholipids of the general Formula I ##STR1## and methods for the treatment of humans suffering from high blood-pressure (hypertension), from inflammatory illnesses, from tumors and/or atherosclerosis by administering medicame |
| 4552869 |
O-Alkyl-O-carbamoylglycerophosphocholines and the use for treating hypertension |
November 12, 1985 |
| The present invention relates to new O-alkyl-O-carbamoylglycerophosphocholines of the general formulae I or II ##STR1## and processes for treating human beings suffering from diseases caused by hypertension by administering one or several of the above compounds. |
| 4551455 |
Method of treating high blood pressure using 6-[4-(1-imidazolyl)-phenyl]-5-methyl-3-oxo-tetrahyd |
November 5, 1985 |
| The present invention relates to new 6-[Imidazolyl-phenyl]-5-methyl-3-oxo-tetrahydropyridazines of the general formula I ##STR1## as well as their acid addition salts, methods for their use, and pharmaceutical preparations containing them. |
| 4550168 |
Benzisoselenazolones and a process for the treatment of inflammatory diseases |
October 29, 1985 |
| The invention relates to new benzisoselenazolones of the general formula I ##STR1## and a process for the treatment of humans suffering from inflammatory diseases of the rheumatic type. |
| 4518783 |
Process for producing (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene |
May 21, 1985 |
| This invention relates to processes for producing the (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for lowering the blood pressure in human beings suffering from increased blood pressure, |
| 4507298 |
6-{4-(.omega.-(1-imidazolyl)-alkyl-phenyl}-3-oxo-2,3,4,5-tetrahydro- pyridazines and acid additio |
March 26, 1985 |
| The invention relates to new 6-{4-(.omega.-(1-imidazolyl)-alkyl)-phenyl}-3-oxo-2,3,4,5-tetrahydro-pyrid azines having the general formula I ##STR1## and acid addition salts thereof, and to a process for the treatment of inflammatory, atherosclerotic and thromboembolic diseases esp |
| 4504479 |
6-{5-[.omega.-(1-Imidazolyl)-alkyl] -thien-2-yl}-3-oxo-2,3,4,5-tetrahydro-pyridazines and acid ad |
March 12, 1985 |
| The invention relates to new 6-{5-[.omega.-(1-imidazolyl)-alkyl]-thien-2-yl}-3-oxo-2,3,4,5-tetrahydro-p yridazines having the general formula I ##STR1## and acid addition salts thereof and to a process for the treatment of inflammatory, atherosclerotic and thrombo-embolic diseases |
| 4497157 |
Process for filling pharmaceutical products containing phospholipides and highly viscous at room |
February 5, 1985 |
| The present invention is related to a process for filling pharmaceutical products which contain 10 to 98% by weight of a phospholipide and which are highly viscous at room temperature, into hard capsules by admixing to such products a solvent or mixture of solvents in particular amounts, |
| 4496486 |
Method for the preparation of phosphatidyl choline of low oil content |
January 29, 1985 |
| An improved method is provided for the preparation of phosphatidyl choline having a low oil content. An alcohol and oil-containing phosphatide solution is admixed with an amount of water sufficient to cause oil present therein to separate from the solution. The oil is removed from the |
| 4482474 |
Phospholipid solutions |
November 13, 1984 |
| Aqueous phospholipid solutions and their preparations, consisting of phospholipids and a solution promoter of the general formula CH.sub.3 (CH.sub.2).sub.n CONHCH.sub.2 CH.sub.2 OH, in which n is 3, 4 or 5. |
| 4464379 |
Indol acetic acid derivatives and anti-inflamatory and related uses thereof |
August 7, 1984 |
| The present invention is related to new indol acetic acid derivatives having the general formula ##STR1## the salts thereof, processes for producing the same and pharmaceutical preparations comprising the same as well as their use as drugs having antithrombotic, antiarteriosclero |
| 4460598 |
Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of th |
July 17, 1984 |
| The invention relates to new triphenylimidazolyloxyalkanoic acids of the general formula I ##STR1## and a process for the treatment of thromboembolic, inflammatory and/or atherosclerotic diseases in humans by using the same. |
| 4454068 |
Cycloalkyl derivatives of benzisoselenazolones |
June 12, 1984 |
| The invention relates to new benzisoselenazolones of the general formula I ##STR1## and to the use thereof in the treatment of inflammatory diseases in humans. |
| 4452743 |
Process for the separation of oils and/or phosphatidylethanolamine from alcohol soluble phosphat |
June 5, 1984 |
| The present invention is related to a new process for the separation of oil and/or phosphatidylethanolamine from alcohol soluble phosphatidylcholine products containing the same thus producing, by chromatography on silicic acid gel in a lower alkanol containing 1 to 4 carbon atoms as sol |
